- Serum osteocalcin levels in overweight children
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Oh SB, Lee WY, Nam HK, Rhie YJ, Lee KH
- KMID: 2452086
- Ann Pediatr Endocrinol Metab.
- 2019 Jun;24(2):104-107.
- doi: 10.6065/apem.2019.24.2.104
PURPOSE: Bone plays a role in glucose metabolism through the release of uncarboxylated osteocalcin into the systemic circulation. The identified novel roles for osteocalcin include increasing insulin secretion and sensitivity,... -
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- Acanthosis nigricans as a clinical marker of insulin resistance among overweight adolescents
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Videira-Silva A, Albuquerque C, Fonseca H
- KMID: 2452085
- Ann Pediatr Endocrinol Metab.
- 2019 Jun;24(2):99-103.
- doi: 10.6065/apem.2019.24.2.99
PURPOSE: Acanthosis nigricans (AN) is a hyperpigmented dermatosis associated with obesity and insulin resistance (IR). There is no consensus whether AN extension scoring offers added value to the clinical estimation... -
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- Risk of cancer in patients treated with recombinant human growth hormone in childhood
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Cianfarani S
- KMID: 2452084
- Ann Pediatr Endocrinol Metab.
- 2019 Jun;24(2):92-98.
- doi: 10.6065/apem.2019.24.2.92
Recombinant human growth hormone (GH) has been in use for over 30 years, and its indications have gradually expanded from the classical replacement therapy in GH deficiency (GHD) to pharmacological... -
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- Thyrotoxic hypokalemic periodic paralysis due to Graves' disease in 2 adolescents
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Roh JG, Park KJ, Lee HS, Hwang JS
- KMID: 2452091
- Ann Pediatr Endocrinol Metab.
- 2019 Jun;24(2):133-136.
- doi: 10.6065/apem.2019.24.2.133
Thyrotoxic periodic paralysis (TPP) is a notable and potentially lethal complication of thyrotoxicosis, and Graves' disease is the most common cause of TPP. TPP is commonly reported in Asian males... -
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- Update on the current modalities used to screen high risk youth for prediabetes and/or type 2 diabetes mellitus
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Brar PC
- KMID: 2452082
- Ann Pediatr Endocrinol Metab.
- 2019 Jun;24(2):71-77.
- doi: 10.6065/apem.2019.24.2.71
The modalities currently employed to screen for type 2 diabetes mellitus (T2DM)/prediabetes are HbA1(c), fasting plasma glucose (FPG), and 2-hour plasma glucose (PG) during an oral glucose tolerance test (OGTT).... -
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- Neonatal transient pseudohypoparathyroidism: could it be included among inactivating parathyroid hormone (PTH)/PTH-related protein signalling disorders?
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De Rose DU, Perri A, Gallini F, Priolo F, Tiberi E, Vento G, Zecca E
- KMID: 2452090
- Ann Pediatr Endocrinol Metab.
- 2019 Jun;24(2):129-132.
- doi: 10.6065/apem.2019.24.2.129
We report a case of transient pseudohypoparathyroidism in a full-term newborn that presented at 20 hours of life with hypocalcemic seizures, hyperphosphatemia and raised parathormone levels. The diagnosis of pseudohypoparathyroidism... -
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- Early-life exposure to endocrine-disrupting chemicals and pubertal development in girls
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Lee JE, Jung HW, Lee YJ, Lee YA
- KMID: 2452083
- Ann Pediatr Endocrinol Metab.
- 2019 Jun;24(2):78-91.
- doi: 10.6065/apem.2019.24.2.78
Over the last decades, the onset of puberty in girls has occurred earlier, but the tempo of pubertal progression has been relatively slower, resulting in a younger age at puberty... -
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- Iodine status and characteristics of Korean adolescents and their parents based on urinary iodine concentration: a nationwide cross-sectional study
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Choi YC, Cheong JI, Chueh HW, Yoo JH
- KMID: 2452087
- Ann Pediatr Endocrinol Metab.
- 2019 Jun;24(2):108-115.
- doi: 10.6065/apem.2019.24.2.108
PURPOSE: Iodine is a major component of thyroid hormones. Both deficiency and excess of iodine are major risk factors for thyroid disease, making it important to accurately assess iodine level... -
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- A case of vitamin D hydroxylation-deficient rickets type 1A caused by 2 novel pathogenic variants in CYP27B1 gene
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Kim YM, Jang YY, Jeong JE, Park HJ, Jang JH, Kim JK
- KMID: 2452092
- Ann Pediatr Endocrinol Metab.
- 2019 Jun;24(2):137-141.
- doi: 10.6065/apem.2019.24.2.137
Vitamin D hydroxylation-deficient rickets type 1A (VDDR1A, OMIM 264700) is a rare autosomal recessive inherited disorder. Pathogenic variants in the CYP27B1 gene lead to loss of 1α-hydroxylase activity. We report... -
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- Comparing adult height gain and menarcheal age between girls with central precocious puberty treated with gonadotropin-releasing hormone agonist alone and those treated with combined growth hormone therapy
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Kim MS, Koh HJ, Lee GY, Kang DH, Kim SY
- KMID: 2452088
- Ann Pediatr Endocrinol Metab.
- 2019 Jun;24(2):116-123.
- doi: 10.6065/apem.2019.24.2.116
PURPOSE: This study aimed to investigate the outcomes of gonadotropin-releasing hormone agonist (GnRHa) therapy with or without growth hormone (GH) therapy for girls with idiopathic central precocious puberty (CPP). METHODS: The... -
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- Thyroid function in girls with central precocious puberty
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Jung G, Oh SB, Lee WY, Kim HR, Nam HK, Kim JH, Rhie YJ, Lee KH
- KMID: 2452089
- Ann Pediatr Endocrinol Metab.
- 2019 Jun;24(2):124-128.
- doi: 10.6065/apem.2019.24.2.124
PURPOSE: Obesity is a well-known risk factor for central precocious puberty (CPP). Recently, elevated thyroid stimulating hormone (TSH) was reported in obese youth. However, few data regarding the relationship between... -
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