- Acidic Fibroblast Growth Factor in Spinal Cord Injury
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Ko CC, Tu TH, Wu JC, Huang WC, Cheng H
- KMID: 2469049
- Neurospine.
- 2019 Dec;16(4):728-738.
- doi: 10.14245/ns.1836216.108
Spinal cord injury (SCI), with an incidence rate of 246 per million person-years among adults in Taiwan, remains a devastating disease in the modern day. Elderly men with lower socioeconomic... -
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- Worsened survival in the head-up tilt position cardiopulmonary resuscitation in a porcine cardiac arrest model
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Park YJ, Hong KJ, Shin SD, Kim TY, Ro YS, Song KJ, Ryu HH
- KMID: 2459804
- Clin Exp Emerg Med.
- 2019 Sep;6(3):250-256.
- doi: 10.15441/ceem.18.060
OBJECTIVE: Head elevation at an angle of 30° during cardiopulmonary resuscitation (CPR) was hemodynamically beneficial compared to supine position in a previous porcine cardiac arrest experimental study. However, survival benefit... -
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- Proposal of conditional random inter-stimulus interval method for unconstrained enclosure based GPIAS measurement systems
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Choe Y, Park I
- KMID: 2470031
- Biomed Eng Lett.
- 2019 Aug;9(3):367-374.
- doi: 10.1007/s13534-019-00109-9
Gap prepulse inhibition of acoustic startle (GPIAS) method has been used effectively for the objective assessment of tinnitus in animals. Among two types of enclosures for the GPIAS, the unconstrained... -
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- Photobiomodulation as a treatment for neurodegenerative disorders: current and future trends
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Hong N
- KMID: 2470030
- Biomed Eng Lett.
- 2019 Aug;9(3):359-366.
- doi: 10.1007/s13534-019-00115-x
Photobiomodulation (PBM) is a rapidly growing as an innovative therapeutic modality for various types of diseases in recent years. Neuronal degeneration is irreversible process and it is proven to be... -
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- Optical coherence tomography angiography in preclinical neuroimaging
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Choi WJ
- KMID: 2470026
- Biomed Eng Lett.
- 2019 Aug;9(3):311-325.
- doi: 10.1007/s13534-019-00118-8
Preclinical neuroimaging allows for the assessment of brain anatomy, connectivity, and function in laboratory animals, such as mice and this imaging field has been a rapidly growing aimed at bridging... -
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- The Lymphatic Drainage Pattern of Internal Mammary Sentinel Lymph Node Identified by Small Particle Radiotracer ((99m)Tc-Dextran 40) in Breast
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Cao XS, Yang GR, Cong BB, Qiu PF, Wang YS
- KMID: 2464395
- Cancer Res Treat.
- 2019 Apr;51(2):483-492.
- doi: 10.4143/crt.2018.062
PURPOSE: The purpose of this study was to detect the lymphatic drainage pattern of internal mammary area and verify the concept of internal mammary sentinel lymph node (IM-SLN) in breast. MATERIALS... -
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- A comparison of metabolomic changes in type-1 diabetic C57BL/6N mice originating from different sources
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Lee S, Kwak JH, Kim SH, Yun J, Cho JY, Kim K, Hwang D, Jung YS
- KMID: 2459300
- Lab Anim Res.
- 2018 Dec;34(4):232-238.
- doi: 10.5625/lar.2018.34.4.232
Animal models have been used to elucidate the pathophysiology of varying diseases and to provide insight into potential targets for therapeutic intervention. Although alternatives to animal testing have been proposed... -
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- Effects of High Concentrations of Naftopidil on Dorsal Root-Evoked Excitatory Synaptic Transmissions in Substantia Gelatinosa Neurons In Vitro
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Uta D, Hattori T, Yoshimura
- KMID: 2431866
- Int Neurourol J.
- 2018 Dec;22(4):252-259.
- doi: 10.5213/inj.1836146.073
PURPOSE: Naftopidil ((±)-1-[4-(2-methoxyphenyl) piperazinyl]-3-(1-naphthyloxy) propan-2-ol) is prescribed in several Asian countries for lower urinary tract symptoms suggestive of benign prostatic hyperplasia. Previous animal experiments showed that intrathecal injection of naftopidil... -
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- A portable high-intensity focused ultrasound system for the pancreas with 3D electronic steering: a preclinical study in a swine model
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Chang W, Lee JY, Lee JH, Bae JS, Cho YJ, Kang KJ, Son K, Chung YR, Lee KB, Han JK
- KMID: 2422356
- Ultrasonography.
- 2018 Oct;37(4):298-306.
- doi: 10.14366/usg.17048
PURPOSE: The aim of this animal study was to evaluate the safety and feasibility of a portable, ultrasonography-guided, high-intensity focused ultrasound (USg-HIFU) system to treat the pancreas. METHODS: Eight swine were... -
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- Specification of Subject Sex in Oncology-Related Animal Studies
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Lee S, Kim WJ, Jeon Y, Lim CH, Sun K
- KMID: 2436330
- Acute Crit Care.
- 2018 Aug;33(3):178-184.
- doi: 10.4266/acc.2017.00444
BACKGROUND: Growing evidence for clinically significant differences between the sexes has attracted the attention of researchers. However, failures to report a test animal sex and balance the sex ratios of... -
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- Electrodeless conductivity tensor imaging (CTI) using MRI: basic theory and animal experiments
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Sajib SZ, Kwon OI, Kim HJ, Woo EJ
- KMID: 2434895
- Biomed Eng Lett.
- 2018 Aug;8(3):273-282.
- doi: 10.1007/s13534-018-0066-3
The electrical conductivity is a passive material property primarily determined by concentrations of charge carriers and their mobility. The macroscopic conductivity of a biological tissue at low frequency may exhibit... -
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- Does pediatric anesthesia cause brain damage? – Addressing parental and provider concerns in light of compelling animal studies and seemingly ambivalent human data
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Lee JR, Loepke AW
- KMID: 2418525
- Korean J Anesthesiol.
- 2018 Aug;71(4):255-273.
- doi: 10.4097/kja.d.18.00165
Anesthesia facilitates surgery in millions of young children every year. Structural brain abnormalities and functional impairment observed in animals have created substantial concerns among clinicians, parents, and government regulators. Clinical... -
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- Locacorten Vioform Ototoxicity Upon Guinea Pig Middle Ear Application
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Woods O, Saliba I
- KMID: 2415946
- J Audiol Otol.
- 2018 Apr;22(2):75-79.
- doi: 10.7874/jao.2017.00199
BACKGROUND AND OBJECTIVES: Locacorten Vioform (Novartis UK) is frequently prescribed for otomycosis. Its component, Clioquinol, also has anti-bacterial properties. Up to this point, its ototoxic potential has not been evaluated.... -
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- Evaluation of Lumbar Intervertebral Disc Degeneration Using T1Ï and T2 Magnetic Resonance Imaging in a Rabbit Disc Injury Model
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Ishikawa T, Watanabe A, Kamoda H, Miyagi M, Inoue G, Takahashi , Ohtori S
- KMID: 2410852
- Asian Spine J.
- 2018 Apr;12(2):317-324.
- doi: 10.4184/asj.2018.12.2.317
STUDY DESIGN: An in vivo histologic and magnetic resonance imaging (MRI) study of lumbar intervertebral disc (IVD) degeneration was conducted. PURPOSE: To clarify the sensitivity and efficacy of T1Ï/T2 mapping for... -
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- The Role of Beta-Tricalcium Phosphate-Hydrogel Scaffold and Mesenchymal Stem Cells on Neogenic Bone Formation
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Lee DR, Kang YK
- KMID: 2410062
- J Korean Orthop Assoc.
- 2018 Apr;53(2):143-151.
- doi: 10.4055/jkoa.2018.53.2.143
PURPOSE: The purpose of this paper was to determine the ability of a mixture consisting of mesenchymal stem cells, beta-tricalcium phosphate β-TCP), and hydrogel, to support cells and form new... -
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- Anti-coccidial activity of the ethanol extract of Tribulus terrestris fruits on Eimeria tenella
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Hong S, Moon MN, Im EK, Won JS, Yoo JH, Kim O
- KMID: 2430885
- Lab Anim Res.
- 2018 Mar;34(1):44-47.
- doi: 10.5625/lar.2018.34.1.44
Anti-coccidial effects of the fruits of Tribulus terrestris (Tribuli fructus) ethanol extract (TTE) were studied with animal experiment following per oral administration with Eimeria (E.) tenella. This experiment was performed... -
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- Ensuring reproducibility and ethics in animal experiments reporting in Korea using the ARRIVE guideline
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Nam MH, Chun MS, Seong JK, Kim HG
- KMID: 2430881
- Lab Anim Res.
- 2018 Mar;34(1):11-19.
- doi: 10.5625/lar.2018.34.1.11
The aim of this study is to evaluate the reporting quality of animal experiments in Korea using the Animals in Research: Reporting In Vivo Experiments (ARRIVE) guideline developed in 2010... -
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- The Efficacy and Underlying Mechanism of Moxibustion in Preventing Cognitive Impairment: A Systematic Review of Animal Studies
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Choe S, Cai M, Jerng UM, Lee JH
- KMID: 2405304
- Exp Neurobiol.
- 2018 Feb;27(1):1-15.
- doi: 10.5607/en.2018.27.1.1
Cognitive impairment is age-related and manageable only with early diagnosis and prevention. Moxibustion is widely accepted in East Asia as useful for preventing cognitive impairment. This systematic review of animal... -
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- Endoscopic Treatment for Pancreatic Cystic Lesions
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Lee SH
- KMID: 2402800
- Korean J Gastroenterol.
- 2018 Jan;71(1):10-17.
- doi: 10.4166/kjg.2018.71.1.10
The decision of the appropriate treatment for pancreatic cystic lesions (PCLs) is becoming increasingly important as the number of incidentally found PCLs increases. A range of modalities have been attempted... -
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- Animal Experimentation for Bariatric Surgery
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Ha TK
- KMID: 2397937
- J Metab Bariatr Surg.
- 2017 Dec;6(2):25-29.
- doi: 10.17476/jmbs.2017.6.2.25
Bariatric surgery is considered the most effective treatment for reducing and maintaining weight for morbid obesity. Moreover, this surgery not only reduces weight but also improves comorbidity. However, concern about... -
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