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The role of soluble common gamma chain in autoimmune disease

Lee B, Hong C

The common gamma chain (gammac) is the central signaling unit for a number of cytokine receptors collectively known as the gammac cytokine receptor family. gammac is critical for ligand binding...
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Mechanistic insights into pancreatic beta-cell mass regulation by glucose and free fatty acids

Oh YS

Pancreatic islets are responsible for blood glucose homeostasis. Reduced numbers of functional (insulin-secreting) beta-cells in pancreatic islets underlies diabetes. Restoration of the secretion of the proper amount of insulin is...
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Glioblastoma specific antigens, GD2 and CD90, are not involved in cancer stemness

Woo SR, Oh YT, An JY, Kang BG, Nam DH, Joo KM

Glioblastoma multiforme (GBM) is the most malignant World Health Organization grade IV brain tumor. GBM patients have a poor prognosis because of its resistance to standard therapies, such as chemotherapy...
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Unduly extensive uncinate process of pancreas in conjunction with pancreatico-duodenal fold

Gandhi S, Sharma M, Pakhiddey , Thakur A, Mehta V, Suri RK, Rath G

Anatomical variations of pancreatic head and uncinate process are rarely encountered in clinical practice. These variations are primarily attributed to the complex development of the pancreas. An unduly enlarged uncinate...
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Expression of SIRT1 and SIRT3 varies according to age in mice

Kwon Y, Kim J, Lee CY, Kim H

Sirtuins (SIRTs) are involved in multiple cellular processes including those related to aging, cancer, and a variety of cellular functions including cell cycle progression, DNA repair, and cellular proliferation. SIRTs...
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When morphogenetic proteins encounter special extracellular matrix and cell-cell connections at the interface of the renal stem/progenitor cell niche

Minuth WW, Denk L

Reciprocal exchange of morphogenetic proteins between epithelial and mesenchymal cells in a stem/progenitor cell niche results in formation of a nephron. To maintain diffusion of morphogenetic proteins, it is assumed...
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Morphological assessment of the anterior loop of the mandibular canal in Koreans

Yu SK, Kim S, Kang SG, Kim JH, Lim KO, Hwang SI, Kim HJ

The mandibular canal divides into the mental and incisive canals at the premolar region, forms the anterior loop which crosses anterior to the mental foramen, and turns back to reach...
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Cisplatin induces primary necrosis through poly(ADP-ribose) polymerase 1 activation in kidney proximal tubular cells

Park S, Yoon SP, Kim J

Treatment with cisplatin for cancer therapy has a major side effect such as nephrotoxicity; however, the role of poly (ADP-ribose) polymerase 1 (PARP1) in necrosis in response to cisplatin nephrotoxicity...
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Variations of the cubital superficial vein investigated by using the intravenous illuminator

Lee H, Lee SH, Kim SJ, Choi WI, Lee JH, Choi IJ

The purpose of this study was to report variations of the cubital superficial vein patterns in the Korean subjects, which was investigated by using venous illuminator, AccuVein. The 200 Korean...
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Innervation of submandibular and sublingual glands in elderly donated cadavers: a preliminary histological study of differences in nerve morphology between mucous and serous acini

Asakawa S, Yamamoto M, Katori Y, Murakami G, Kasahara M, Matsunaga , Abe SI

We examined morphological differences between the sublingual and submandibular glands with special reference to their innervation. The sublingual gland contained abundant periodic acid Schiff-positive mucous acini: some lobules were composed...
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Neurosphere and adherent culture conditions are equivalent for malignant glioma stem cell lines

Rahman M, Reyner K, Deleyrolle L, Millette S, Azari H, Day BW, Stringer B, Boyd AW, Johns TG, Blot V, Duggal R, Reynolds B

Certain limitations of the neurosphere assay (NSA) have resulted in a search for alternative culture techniques for brain tumor-initiating cells (TICs). Recently, reports have described growing glioblastoma (GBM) TICs as...
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