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Induced pluripotent stem cells and personalized medicine: current progress and future perspectives

Chun YS, Byun K, Lee B

Generation of induced pluripotent stem cells (iPSCs) has revolutionized the field of regenerative medicine by providing researchers with a unique tool to derive disease-specific stem cells for study. iPSCs can...
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Prospect of cell therapy for Parkinson's disease

Pawitan JA

The hallmark of Parkinson's disease is on-going degeneration of dopaminergic neurons in the substantia nigra, which may be due to various etiologies. Various approaches to alleviate symptoms are available, such...
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Laminar flow activation of ERK5 leads to cytoprotective effect via CHIP-mediated p53 ubiquitination in endothelial cells

Lim JH, Woo CH

Atherosclerosis is readily observed in areas where disturbed flow is formed, while the atheroprotective region is found in areas with steady laminar flow (L-flow). It has been established that L-flow...
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Increase in concentration of soluble HLA-G in high-quality embryos after intracytoplasmic sperm injection

Heidari MH, Novin MG, Ahmadi F, Khorshid M, Najafi T, Molouki A, Salehpour , Bandehpour M, Heidari M, Sato E

Non-invasive methods are normally preferred to conventional invasive methods when selecting suitable embryos to improve pregnancy rates after assisted reproduction techniques. One of the most recognized non-invasive methods is to...
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The use of Stronger Neo-Minophagen C, a glycyrrhizin-containing preparation, in robust neuroprotection in the postischemic brain

Kim SW, Lim CM, Lee HK, Lee JK

Stronger Neo-Minophagen C (SNMC) is a glycyrrhizin-containing preparation that is approved in Japan for the treatment of chronic hepatic diseases and is marketed in Japan, China, Korea, Taiwan, and India....
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A simple technique for morphological measurement of cerebral arterial circle variations using public domain software (Osiris)

Ansari S, Dadmehr M, Eftekhar B, McConnell , Ganji S, Azari H, Kamali-Ardakani S, Hoh BL, Mocco J

This article describes a straightforward method to measure the dimensions and identify morphological variations in the cerebral arterial circle using the general-purpose software program Osiris. This user-friendly and portable program...
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Histological and immunohistochemical studies on the epididymal duct in the dromedary camel (Camelus dromedarius)

Alkafafy M, Rashed R, Emara S, Nada M, Helal A

This study was conducted to underscore the spatial distribution of some biologically active proteins within the epididymal duct in the dromedary camel. Paraffin-embedded sections from different regions of epididymis were...
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Morphological and functional evaluation of an animal model for the retinal degeneration induced by N-methyl-N-nitrosourea

Jeong E, Paik SS, Jung SW, Chun MH, Kim IB

The retinal degeneration (RD) is a general cause of blindness. To study its pathophysiology and evaluate the effects of new therapeutic agents before clinical trials, it is essential to establish...
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Morphological evidences in circumvallate papilla and von Ebners' gland development in mice

Sohn WJ, Gwon GJ, An CH, Moon C, Bae YC, Yamamoto H, Lee S, Kim JY

In rodents, the circumvallate papilla (CVP), with its underlying minor salivary gland, the von Ebners' gland (VEG), is located on the dorsal surface of the posterior tongue. Detailed morphological processes...
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Different expressions of AQP1, AQP4, eNOS, and VEGF proteins in ischemic versus non-ischemic cerebropathy in rats: potential roles of AQP1 and eNOS in hydrocephalic and vasogenic edema formation

Kim J, Jung Y

In this study, expressions of aquaporin (AQP) 1, AQP4, endothelial nitric oxide synthase (eNOS), and vascular endothelial growth factor in blood-cerebrospinal fluid (CSF) barrier and blood-brain barrier (BBB) are examined...
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