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Genomics and proteomics in stem cell research: the road ahead

Ahn SM, Simpson R, Lee B

Stem cell research has been widely studied over the last few years and has attracted increasing attention from researchers in all fields of medicine due to its potential to treat...
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TBR2-immunopsitive unipolar brush cells are associated with ectopic zebrin II-immunoreactive Purkinje cell clusters in the cerebellum of scrambler mice

Chung SH, Kim CT, Jeong YG, Lee NS

Unipolar brush cells (UBCs) are excitatory interneurons with their somata located in the granular layer. Recently, T-brain factor 2 (Tbr2) was shown to be expressed in a subset of UBCs...
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Early cerebellar granule cell migration in the mouse embryonic development

Chung SH, Kim CT, Jung YH, Lee NS, Jeong YG

Pax6, a paired homeobox DNA binding protein, has been found to be expressed in the cerebellum in both granule cells and their precursors in the external granular layer (EGL). In...
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Effects of repeated restraint stress on platelet endothelial cell adhesion molecule-1 immunoreactivity and protein levels in the gerbil hippocampus after transient cerebral ischemia

Park OK, Lee CH, Hwang IK, Yoo KY, Choi JH, Won MH

Stress has long been known to be a causative factor of various disease states. In this study, we investigated the effects of repeated restraint stress on platelet endothelial cell adhesion...
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Inhibitory effects of curcumin on passive cutaneous anaphylactoid response and compound 48/80-induced mast cell activation

Choi YH, Yan GH, Chai OH, Song CH

Mast cells participate in allergies and inflammation by secreting a variety of pro-inflammatory mediators. Curcumin, the active component of turmeric, is a polyphenolic phytochemical with anti-tumor, anti-inflammatory, anti-oxidative, and anti-allergic...
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Immunohistochemical study on the expression of calcium binding proteins (calbindin-D28k, calretinin, and parvalbumin) in the cerebellum of the nNOS knock-out(-/-) mice

Lee JC, Chung YH, Cho YJ, Kim J, Kim N, Cha CI, Joo KM

Nitric Oxide (NO) actively participates in the regulation of neuronal intracellular Ca2+ levels by modulating the activity of various channels and receptors. To test the possibility that modulation of Ca2+...
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Chromatin organization and transcriptional activation of Hox genes

Lee JY, Min H, Wang X, Khan AA, Kim MH

Spatially and temporally programmed expression of the Hox genes along the antero-posterior (A-P) axis is essential for correct pattern formation during embryonic development. An accumulating body of evidence indicates the...
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Vitamin C acts indirectly to modulate isotype switching in mouse B cells

Woo A, Kim JH, Jeong YJ, Maeng HG, Lee YT, Kang JS, Lee WJ, Hwang YI

Vitamin C, one of essential micronutrients, has been reported to modulate the humoral immune responses in some mammals. We investigated whether vitamin C might modulate this response in mice by...
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Surgical anatomy of the lower eyelid relating to lower blepharoplasty

Hwang K

The aim of this review is to familiarize the reader with the critical lower eyelid anatomy as is related to lower blepharoplasty or a midface lift. The contents include 1)...
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Recovered changes in the spleen by agmatine treatment after transient cerebral ischemia

Uranchimeg D, Kim JH, Kim JY, Lee WT, Park KA, Batbaatar , Tundevrentsen S, Amgalanbaatar D, Lee JE

Stroke or cerebrovascular injury is the leading cause of disability and the third leading cause of deaths worldwide. After the initial ischemic injury, sympathetic signals are transmitted to the spleen...
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