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A Compound Mutation (c.953C < G and c.49G < A) Aggravates Functional Impairments of C1-INH in Hep G2 Cells

Xu YY, Zhi YX

No abstract available.
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The Relevance of Nasal Cytology in the Workup of House Dust Mite-Induced Allergic Rhinitis

Gelardi M, Puccinelli P, Incorvaia , Passalacqua G, Ciprandi G, Italian Cometa Study Group

No abstract available.
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Chamber and Field Studies demonstrate Differential Amb a 1 Contents in Common Ragweed Depending on COâ‚‚ Levels

Choi YJ, Oh HR, Oh JW, Kim KR, Kim MJ, Kim BJ, Baek WG

Although atmospheric carbon dioxide (COâ‚‚) has no apparent direct effect on human health, it does have direct effects on plants. The present study evaluated the influence of increased COâ‚‚ levels...
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Immune Characterization of Bone Marrow-Derived Models of Mucosal and Connective Tissue Mast Cells

Benedé S, Cody E, Agashe C, Berin MC

PURPOSE: It is well appreciated that mast cells (MCs) demonstrate tissue-specific imprinting, with different biochemical and functional properties between connective tissue MCs (CTMCs) and mucosal MCs (MMCs). Although in vitro...
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Overexpression of miR-155-5p Inhibits the Proliferation and Migration of IL-13-Induced Human Bronchial Smooth Muscle Cells by Suppressing TGF-β-Activated Kinase 1/MAP3K7-Binding Protein 2

Shi Y, Fu X, Cao Q, Mao Z, Chen Y, Sun Y, Liu Z, Zhang Q

PURPOSE: Molecular mechanisms leading to asthma is still ill-defined. Though the function of microRNAs (miRNAs) in asthma was previously reported, the involvement of miR-155 in important features of this disease...
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Current Management of Moderate-to-Severe Atopic Dermatitis: A Survey of Allergists, Pediatric Allergists and Dermatologists in Korea

Yum HY, Kim HH, Kim HJ, Kim WK, Lee SY, Li K, Lee DH, The KAAACI Work Group on Severe/Recalcitrant Atopic Dermatitis

PURPOSE: There is an unmet need for the treatment of moderate-to-severe atopic dermatitis (AD), leading to variation in management strategies. To investigate distinct features and treatment modalities according to physicians'...
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Differences in Genetic Variations Between Treatable and Recalcitrant Atopic Dermatitis in Korean

Jun M, Wang HY, Lee S, Choi E, Lee H, Choi EH

PURPOSE: Variations in barrier- or immune response-related genes are closely related to the development of atopic dermatitis (AD). This study was designed to identify genetic variations and clinical features to...
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Analysis of Peripheral B Cell Subsets in Patients With Allergic Rhinitis

Luo J, Guo H, Liu Z, Peng T, Hu X, Han M, Yang X, Zhou X, Li H

PURPOSE: Recent evidence suggests that B cells can both promote and inhibit the development and progression of allergic disease. However, the characteristics of B cell subsets in patients with allergic...
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Perceptions of Severe Asthma and Asthma-COPD Overlap Syndrome Among Specialists: A Questionnaire Survey

Kim SH, Moon JY, Lee JH, Ban GY, Kim S, Kim MA, Kim JH, Kim MH, Park CS, Park SY, Kwon HS, Kwon JW, Jung JW, Kang HR, Park JS, Kim TB, Park HW, Cho YS, Yoo KH, Oh YM, Lee BJ, Jang AS, Cho SH, Park HS, Park CS, Yoon HJ, on behalf of the Severe Asthma Work Group, the Korean Academy of Asthma, Allergy and Clinical Immunology

PURPOSE: Severe asthma and asthma-chronic obstructive pulmonary disease (COPD) overlap syndrome (ACOS) are difficult to control and are often associated with poor clinical outcomes. However, much is not understood regarding...
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TRPV1 Blocking Alleviates Airway Inflammation and Remodeling in a Chronic Asthma Murine Model

Choi JY, Lee HY, Hur J, Kim KH, Kang JY, Rhee CK, Lee SY

PURPOSE: Asthma is a chronic inflammatory airway disease characterized by airway hyperresponsiveness (AHR), inflammation, and remodeling. There is emerging interest in the involvement of the transient receptor potential vanilloid 1...
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Significance of Skin Barrier Dysfunction in Atopic Dermatitis

Kim BE, Leung DY

The epidermis contains epithelial cells, immune cells, and microbes which provides a physical and functional barrier to the protection of human skin. It plays critical roles in preventing environmental allergen...
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Allergen-Specific Immunotherapies for Food Allergy

Feuille E, Nowak-Wegrzyn A

With rising prevalence of food allergy (FA), allergen-specific immunotherapy (AIT) for FA has become an active area of research in recent years. In AIT, incrementally increasing doses of inciting allergen...
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The Emerging Role of TRPV1 in Airway Inflammation

Kim JH

No abstract available.
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