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Real-Life Clinical Use of Symbicort® Maintenance and Reliever Therapy for Asthmatic Patients in Korea

Kim SH, Kim TB, Kim SH, Park HW, Song SH, Jeong JW, Jee YK, Park SW, Kim MS, Yoon HJ

The aim of this study was to examine the daily practice patterns of Symbicort® Maintenance and Reliever Therapy (SMART) in Korean asthmatic patients and to analyze clinical signs related to...
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Clinical Course of Chronic Spontaneous Urticaria in the Korean Adult Population

Kim YS, Park SH, Han K, Lee JH, Kim NI, Roh JY, Seo SJ, Song HJ, Lee MG, Choi JH, Park YM

Knowledge of the clinical course of chronic spontaneous urticaria (CSU) remains unclear. The purpose of our study was to investigate the clinical course of CSU in the Korean adult population....
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T-Helper Type 2 Cells Direct Antigen-Induced Eosinophilic Skin Inflammation in Mice

Kaminuma O, Nishimura , Kitamura N, Saeki M, Hiroi T, Mori A

Eosinophilic inflammation in combination with immunoglobulin E (IgE) production is a characteristic feature of atopic dermatitis. Although activated T-helper type (Th) 2 cells play critical roles in the local accumulation...
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Detecting Allergens From Black Tiger Shrimp Penaeus monodon That Can Bind and Cross-link IgE by ELISA, Western Blot, and a Humanized Rat Basophilic Leukemia Reporter Cell Line RS-ATL8

Jarupalee , Chatchatee P, Komolpis K, Suratannon N, Roytrakul , Yingchutrakul Y, Yimchuen W, Butta P, Jacquet A, Palaga T

BACKGROUND: Black tiger shrimp Penaeus monodon is one of the common causes of shellfish allergy that is increasing worldwide. One of the important problems in the management of shellfish allergy...
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β₂-Adrenoceptor Blockade Deteriorates Systemic Anaphylaxis by Enhancing Hyperpermeability in Anesthetized Mice

Yang W, Shibamoto , Kuda Y, Zhang T, Tanida M, Kurata Y

PURPOSE: Patients treated with propranolol, a nonselective β-adrenoceptor antagonist, develop severe anaphylaxis, but the mechanism remains unknown. We determined effects of β₁- and β₂-adrenoceptor antagonists on the anaphylaxis-induced increase in...
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Respiratory Function and Symptoms Post Cold Air Exercise in Female High and Low Ventilation Sport Athletes

Kennedy MD, Faulhaber

PURPOSE: Cold weather exercise is common in many regions of the world; however, it is unclear whether respiratory function and symptom worsen progressively with colder air temperatures. Furthermore, it is...
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Chinese Herbal Medicine to Treat Allergic Rhinitis: Evidence From a Meta-Analysis

Zhang X, Lan F, Zhang Y, Zhang L

PURPOSE: Chinese herbal medicine (CHM) has been widely used in China to treat allergic rhinitis (AR). However, several studies have produced conflicting data with regard to the efficacy of the...
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Alteration in Claudin-4 Contributes to Airway Inflammation and Responsiveness in Asthma

Lee PH, Kim BG, Lee SH, Lee JH, Park SW, Kim DJ, Park CS, Leikauf GD, Jang AS

PURPOSE: Claudin-4 has been reported to function as a paracellular sodium barrier and is one of the 3 major claudins expressed in lung alveolar epithelial cells. However, the possible role...
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A Retrospective Study of Clinical Response Predictors in Subcutaneous Allergen Immunotherapy With House Dust Mites for Allergic Rhinitis

Lee JH, Kim SC, Choi H, Jung CG, Ban GY, Shin YS, Nahm DH, Park HS, Ye YM

PURPOSE: House dust mites (HDM) are major allergens that cause allergic rhinitis (AR). Allergen-specific subcutaneous immunotherapy (SCIT) has been shown to be clinically beneficial in many clinical trials. Such trials,...
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Viral Infections and Associated Factors That Promote Acute Exacerbations of Asthma

Kim CK, Callaway Z, Gern JE

Despite asthma being the most common chronic childhood ailment, there is still much to learn about the disease. Early childhood infections with well-known or emerging viruses can lay the pathophysiologic...
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Glycolysis and the Hexosamine Biosynthetic Pathway as Novel Targets for Upper and Lower Airway Inflammation

Kim YH, Nakayama T, Nayak J

Glycolysis is a process that rapidly converts glucose to lactate to produce adenosine triphosphate (ATP) under anaerobic conditions and occurs in all eukaryotic and prokaryotic cells. On the other hand,...
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Claudin may be a Potential Biomarker for Epithelial Barrier Dysfunction in Asthma

Jin HJ, Park HS

No abstract available.
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Efficacy and Safety of Subcutaneous Allergen Immunotherapy for Allergic Rhinitis

Sohn MH

No abstract available.
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