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A Case of Type 2 Hereditary Angioedema With SERPING1 Mutation

Sim DW, Park KH, Lee JH, Park JW

Hereditary angioedema is a disease of congenital deficiency or functional defect in the C1 esterase inhibitor (C1-INH) consequent to mutation in the SERPING1 gene, which encodes C1-INH. This disease manifests...
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Palonosetron-Induced Anaphylaxis During General Anesthesia: A Case Report

Park H, Oh K, Lee H, Lee JH, Kang SM, Park SY, Kwon HS, Cho YS, Moon HB, Kim TB

Palonosetron is a 5-hydroxytryptamine-3 (5-HT-3) receptor antagonist used for preventing postoperative nausea and vomiting. Compared with ondansetron and granisetron, it is a better drug because of prolonged action and minimal...
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Association of MBL With Work-Related Respiratory Symptoms in Bakery Workers

Kim MA, Yoon MK, Kim SH, Park HS

Baker's asthma is the most prevalent occupational asthma, and IgE-mediated response is known as a major pathogenesis. However, recent studies have suggested the involvement of innate immune response because wheat...
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Validation of a Rapid, Robust, Inexpensive Screening Method for Detecting the HLA-B*58:01 Allele in the Prevention of Allopurinol-Induced Severe Cutaneous Adverse Reactions

Nguyen DV, Vida C, Chu HC, Fulton R, Li J, Fernando S

The HLA B*58:01 allele has been worldwide reported as a pharmacogenetic susceptibility to allopurinol-induced severe cutaneous adverse reactions (SCARs). To prevent these life-threatening conditions, the American College of Rheumatology hingly...
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Comorbidities and Phenotypes of Rhinitis in Korean Children and Adolescents: A Cross-sectional, Multicenter Study

Lee KS, Yum HY, Sheen YH, Park YM, Lee YJ, Choi BS, Jee HM, Choi SH, Kim HH, Park Y, Kim HB, Rha YH, Korean Academy of Pediatric Allergy and Respiratory Disease (KAPARD) Work Group on Rhinitis

PURPOSE: Rhinitis is a nasal inflammatory disease in children and adolescents. However, little is known about the phenotypes and characteristics of allergic rhinitis (AR) in Korean children and adolescents. The...
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Inhibition of Allergic Response by Intranasal Selective NF-κB Decoy Oligodeoxynucleotides in a Murine Model of Allergic Rhinitis

Wee JH, Zhang YL, Rhee CS, Kim DY

PURPOSE: It remains unknown whether local inhibition of Nuclear factor-kappa B (NF-κB) could have therapeutic value in the treatment of allergic rhinitis (AR). This study aimed to evaluate the effect...
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Asthma Severity and the Controller Prescription in Children at 12 Tertiary Hospitals

Suh DI, Yang HJ, Kim BS, Shin YH, Lee SY, Park G, Kim WK, Kim HB, Baek H, Kim JK, Kim JT, Lim DH, Asthma Study Group for Preschool Children

PURPOSE: Guidelines need to be tailored to where they are applied. We aimed to describe the distinctive asthma severity profile and the pattern of controller prescription in Korean children. METHODS: Twelve...
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Development and Validation of an Attitudinal-Profiling Tool for Patients With Asthma

David-Wang A, Price D, Cho SH, Ho JC, Liam CK, Neira G, Teh PL, REcognise Asthma and LInk to Symptoms and Experience (REALISE) Asia Working Group

PURPOSE: To develop a profiling tool which accurately assigns a patient to the appropriate attitudinal cluster for the management of asthma. METHODS: Attitudinal data from an online survey of 2,467 patients...
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Oral Food Desensitization in Children With IgE-Mediated Cow's Milk Allergy: Immunological Changes Underlying Desensitization

Perezábad L, Reche M, Valbuena T, López-Fandiño R, Molina E, López-Expósito I

PURPOSE: This study aimed to evaluate the safety and efficacy to induce clinical desensitization to cow's milk (CM) of an oral immunotherapy (OIT) protocol in a pediatric population with cow's...
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Inhibitory Effects of Resveratrol on Airway Remodeling by Transforming Growth Factor-β/Smad Signaling Pathway in Chronic Asthma Model

Lee HY, Kim IK, Yoon HK, Kwon SS, Rhee CK, Lee SY

PURPOSE: Asthma is a chronic airway disease characterized by airway remodeling, leading to a progressive decline in lung function. Therapeutic agents that attenuate airway remodeling can complement the limited effects...
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Personalized Medicine in Allergy

Ferrando M, Bagnasco D, Varricchi , Bernardi S, Bragantini A, Passalacqua G, Canonica G

Allergic disease is among the most common pathologies worldwide and its prevalence has constantly increased up to the present days, even if according to the most recent data it seems...
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Development of New Therapies for Severe Asthma

Fajt ML, Wenzel SE

Persistent asthma has long been treated with inhaled corticosteroids (CSs), as the mainstay of therapy. However, their efficacy in patients with more severe disease is limited, which led to the...
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Resveratrol in Asthma: A French Paradox?

Kim HY

No abstract available.
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