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Dynamics of Gut Microbiota According to the Delivery Mode in Healthy Korean Infants

Lee E, Kim BJ, Kang MJ, Choi KY, Cho HJ, Kim Y, Yang SI, Jung YH, Kim HY, Seo JH, Kwon JW, Kim HB, Lee SY, Hong SJ

Microbial colonization of the infant gut is unstable and shows a wide range of diversity between individuals. Gut microbiota play an important role in the development of the immune system,...
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Genes Involved in Interleukin-1 Receptor Type II Activities Are Associated With Asthmatic Phenotypes

Madore AM, Vaillancourt VT, Bouzigon E, Sarnowski , Monier F, Dizier MH, Demenais F, Laprise C

PURPOSE: Interleukin-1 (IL-1) plays a key role in inflammation and immunity and its decoy receptor, IL-1R2, has been implicated in transcriptomic and genetic studies of asthma. METHODS: Two large asthma family...
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Soluble CD93 as a Novel Biomarker in Asthma Exacerbation

Sigari N, Jalili A, Mahdawi L, Ghaderi E, Shilan M

Asthma research is shifting from studying symptoms and lung functions to the narrow-focus cellular profiles protein analysis, biomarkers, and genetic markers. The transmembrane glycoprotein CD93 is involved in endothelial cell...
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Periostin and Interleukin-13 Are Independently Related to Chronic Spontaneous Urticaria

Bae Y, Izuhara K, Ohta S, Ono J, Hong GU, Ro JY, Park GH, Choi JH

Chronic spontaneous urticaria (CSU) is a complex idiopathic disease of the skin with various cellular infiltrations. Although mast cells are key effector cells in the pathogenesis of CSU, CD4+ T...
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Synergistic Effect of Dermatophagoides farinae and Lipopolysaccharides in Human Middle ear Epithelial Cells

Lee JE, Kim YH, Rhee CS, Kim DY

PURPOSE: Although the concept of "one airway, one disease," which includes the middle ear space as part of the united airway is well recognized, the role of allergens in otitis...
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Vacuolar Serine Protease Is a Major Allergen of Fusarium proliferatum and an IgE-Cross Reactive Pan-Fungal Allergen

Yeh CC, Tai HY, Chou H, Wu KG, Shen HD

PURPOSE: Fusarium species are among prevalent airborne fungi and causative agents of human respiratory atopic disorders. We previously identified a 36.5-kDa F. proliferatum component recognized by IgE antibodies in 9...
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Orthologous Allergens and Diagnostic Utility of Major Allergen Alt a 1

Moreno A, Pineda F, Alcover J, Rodríguez D, Palacios R, Martínez-Naves E

PURPOSE: Hypersensitivity to fungi is associated with rhinoconjunctivitis and asthma. For some fungi, such as Alternaria alternata (A. alternata), the symptoms of asthma are persistent, increasing disease severity and the...
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Systemic Reactions to Dust Mite Subcutaneous Immunotherapy: A 3-Year Follow-up Study

Dong X, Huang N, Li W, Hu L, Wang X, Wang Y, Xiang N, Liu G, Zhu R

PURPOSE: The incidence of allergen specific immunotherapy-related systemic reactions (SRs) varies among different studies, and many factors are likely to contribute to SRs. This study aims to investigate the incidence,...
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Short-, Intermediate-, and Long-Term Changes in Basophil Reactivity Induced by Venom Immunotherapy

Rodríguez Trabado A, Cámara Hijón C, Ramos Cantariño A, Romero-Chala S, García-Trujillo JA, Fernández Pereira LM

PURPOSE: The basophil activation test (BAT) has been used to monitor venom immunotherapy (VIT) due to its high specificity. A previous study has reported a good correlation between a significant...
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Does Spore Count Matter in Fungal Allergy?: The Role of Allergenic Fungal Species

Lin WR, Chen YH, Lee MF, Hsu LY, Tien CJ, Shih FM, Hsiao SC, Wang PH

PURPOSE: Fungi have been known to be important aeroallergens for hundreds of years. Most studies have focused on total fungal concentration; however, the concentration of specific allergenic fungi may be...
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Guideline of Chronic Urticaria Beyond

Fine LM, Bernstein

Urticaria is a relatively common condition that if chronic can persist for weeks, months or years and affect quality of life significantly. The etiology is often difficult to determine, especially...
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Climate Change and Air Pollution: Effects on Respiratory Allergy

D'Amato G, Pawankar R, Vitale C, Lanza M, Molino A, Stanziola , Sanduzzi A, Vatrella A, D'Amato M

A body of evidence suggests that major changes involving the atmosphere and the climate, including global warming induced by anthropogenic factors, have impact on the biosphere and human environment. Studies...
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Does Specific Fungal Allergen Really Matter?

Yoo Y

No abstract available.
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