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New Allergic and Hypersensitivity Conditions Section in the International Classification of Diseases-11

Tanno LK, Calderon M, Demoly P, Joint Allergy Academies

Allergy and hypersensitivity, originally perceived as rare and secondary disorders, are one of the fastest growing conditions worldwide, but not adequately tracked in international information systems, such as the International...
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Autologous Immunoglobulin Therapy in Patients With Severe Recalcitrant Atopic Dermatitis: Long-Term Changes of Clinical Severity and Laboratory Parameters

Nahm DH, Ahn A, Kim ME, Cho SM, Park MJ

This report evaluated long-term changes in clinical severity and laboratory parameters in 3 adult patients with severe recalcitrant atopic dermatitis (AD) who were treated with intramuscular injections of 50 mg...
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House Dust Mite-Derived Chitin Enhances Th2 Cell Response to Inhaled Allergens, Mainly via a TNF-α-Dependent Pathway

Choi JP, Lee SM, Choi HI, Kim MH, Jeon SG, Jang MH, Jee YK, Yang S, Cho YJ, Kim YK

PURPOSE: Chitin is a potent adjuvant in the development of immune response to inhaled allergens in the airways. According to other studies, chitin is known as multi-faced adjuvants which can...
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Characteristics of Anaphylaxis in 907 Chinese Patients Referred to a Tertiary Allergy Center: A Retrospective Study of 1,952 Episodes

Jiang N, Yin J, Wen L, Li H

PURPOSE: Comprehensive evaluation of anaphylaxis in China is currently lacking. In this study, we characterized the clinical profiles, anaphylactic triggers, and emergency treatment in pediatric and adult patients. METHODS: Outpatients diagnosed...
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Response to Nonallergenic Irritants in Children With Allergic and Nonallergic Rhinitis

Baek JH, Cho E, Kim MA, Lee SW, Kang YS, Sheen YH, Jee HM, Jung YH, Han MY

PURPOSE: Nonallergenic irritants can aggravate the symptoms of rhinitis. We investigated the clinical responses of children with allergic rhinitis (AR) and nonallergic rhinitis (NAR) to nonallergenic irritants, and identified factors...
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Age-Related Changes in Immunological Factors and Their Relevance in Allergic Disease Development During Childhood

Chang WS, Kim EJ, Lim YM, Yoon D, Son JY, Park JW, Hong SJ, Cho SH, Lee JS

PURPOSE: Allergic diseases are triggered by Th2-mediated immune reactions to allergens and orchestrated by various immunological factors, including immune cells and cytokines. Although many reports have suggested that childhood is...
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Detection of Allergen Specific Antibodies From Nasal Secretion of Allergic Rhinitis Patients

Kim JH, Yoon MG, Seo DH, Kim BS, Ban GY, Ye YM, Shin YS, Park HS

PURPOSE: Allergic rhinitis (AR) is a common and increasing disease in which Dermatophagoides (D.) farinae is one of the most common causative allergens. The aims of this study were to...
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Omalizumab Improves Quality of Life and Asthma Control in Chinese Patients With Moderate to Severe Asthma: A Randomized Phase III Study

Li J, Kang J, Wang C, Yang J, Wang L, Kottakis I, Humphries , Zhong N, China Omalizumab Study Group

PURPOSE: Omalizumab is the preferred add-on therapy for patients with moderate-to-severe persistent allergic asthma and has demonstrated efficacy and safety in various ethnicities. This study evaluated the efficacy and safety...
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No Concentration Decrease of House Dust Mite Allergens With Rising Altitude in Alpine Regions

Grafetstätter C, Prossegger J, Braunschmid H, Sanovic R, Hahne P, Pichler C, Thalhamer , Hartl A

PURPOSE: Several studies over the past 4 decades have indicated a significant reduction in house dust mite (HDM) and HDM allergen concentration in areas higher than 1,500 m above sea...
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A Double-Blind, Randomized, Crossover Study to Compare the Effectiveness of Montelukast on Atopic Dermatitis in Korean Children

Jeon YH, Min TK, Yang HJ, Pyun BY

PURPOSE: Some studies report a role of leukotrienes in the pathogenesis of atopic dermatitis and suggest a rationale for the use of leukotriene receptor antagonist (LTRA) in the treatment of...
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Update on the Management of Aspirin-Exacerbated Respiratory Disease

Buchheit K, Laidlaw TM

Aspirin-exacerbated respiratory disease (AERD) is an adult-onset upper and lower airway disease consisting of eosinophilic nasal polyps, asthma, and respiratory reactions to cyclooxygenase 1 (COX-1) inhibitors. Management includes guideline-based treatment...
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Allergic Bronchopulmonary Aspergillosis: A Perplexing Clinical Entity

Shah A, Panjabi C

In susceptible individuals, inhalation of Aspergillus spores can affect the respiratory tract in many ways. These spores get trapped in the viscid sputum of asthmatic subjects which triggers a cascade...
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Is Montelukast Benefical in Children With Atopic Dermatitis?

Lee AY

No abstract available.
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