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Hypersensitivity Pneumonitis Caused by Cephalosporins With Identical R1 Side Chains

Lee SH, Kim MH, Lee K, Jo EJ, Park HK

Drug-induced hypersensitivity pneumonitis results from interactions between pharmacologic agents and the human immune system. We describe a 54-year-old man with hypersensitivity pneumonitis caused by cephalosporins with identical R1 side chains....
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Bee Pollen-Induced Anaphylaxis: A Case Report and Literature Review

Choi JH, Jang YS, Oh JW, Kim CH, Hyun IG

Bee pollen is pollen granules packed by honey bees and is widely consumed as natural healthy supplements. Bee pollen-induced anaphylaxis has rarely been reported, and its allergenic components have never...
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Progress and Prospect: A Bibliometric Analysis of Research Papers by Korean Allergists Over Recent Five Years (2009-2013)

Song WJ, Jee HM, Suh DI, Yang HJ, Yoon JS, Yu J, Kim SH, Ye YM, Kim TB, Shin SY, Li K, Kim CW, The KAAACI Scientific Program Committee

Since the establishment of the academic society in 1972, Korean allergists have made continuous efforts to elucidate pathogenic mechanisms and therapeutic advances for allergic diseases. The present study aimed to...
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Enhanced Allergic Inflammation of Der p 2 Affected by Polymorphisms of MD-2 Promoter

Liao EC, Hsieh CW, Chang CY, Yu SJ, Sheu ML, Wu SM, Tsai JJ

PURPOSE: Myeloid differentiation-2 (MD-2) has been associated with endotoxin and inflammatory disorders because it can recognize lipopolysaccharide (LPS) binding and attenuate Toll-like receptor 4 (TLR4)-mediated signaling. However, its role in...
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Human Rhinovirus-induced Proinflammatory Cytokine and Interferon-beta Responses in Nasal Epithelial Cells From Chronic Rhinosinusitis Patients

Kim JH, Kim YS, Cho GS, Kim NH, Gong CH, Lee BJ, Jang YJ

PURPOSE: Asthma exacerbation from human rhinovirus (HRV) infection is associated with deficient antiviral interferon (IFN) secretion. Although chronic rhinosinusitis (CRS), an inflammatory upper airway disease, is closely linked to asthma,...
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Profiles of IgE Sensitization to Der f 1, Der f 2, Der f 6, Der f 8, Der f 10, and Der f 20 in Korean House Dust Mite Allergy Patients

Jeong KY, Lee JY, Son M, Yi MH, Yong TS, Shin JU, Lee KH, Kim YJ, Park KH, Park HJ, Lee JH, Park JW

PURPOSE: Measurement of IgE specific to purified house dust mite (HDM) allergens may improve allergy diagnosis. This study aimed to investigate the sensitization profiles of Korean HDM allergic subjects suffering...
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Activation of the Intrinsic Coagulation Pathway in Patients With Chronic Urticaria

Kim JA, Kim S, Kim JE, Gu JY, Yoo HJ, Kang HR, Kim HK

PURPOSE: Although coagulation activation has been reported in chronic urticaria, data pertaining to detailed changes in coagulation factors and global coagulation status are lacking. The current study evaluated global coagulation...
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The Prevalence of Toxocariasis and Diagnostic Value of Serologic Tests in Asymptomatic Korean Adults

Lee JY, Yang MH, Hwang JH, Kang M, Paeng JW, Yune S, Lee BJ, Choi DC

PURPOSE: Toxocariasis is the most common cause of peripheral blood eosinophilia in Korea and produces eosinophilic infiltration in various organs, including the lung. However, the prevalence of toxocariasis in the...
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Expression and Regulation of Transcription Factor FoxA2 in Chronic Rhinosinusitis With and Without Nasal Polyps

Luo Q, Zhang J, Wang H, Chen F, Luo X, Miao B, Wu X, Ma R, Luo X, Xu G, Shi J, Li H

PURPOSE: Chronic rhinosinusitis (CRS) is characterized by the excessive production of mucus. However, the molecular mechanism underlying mucin overproduction in CRS with or without nasal polyps (CRSwNP and CRSsNP, respectively)...
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Altered microRNA Expression Profiles of Extracellular Vesicles in Nasal Mucus From Patients With Allergic Rhinitis

Wu G, Yang G, Zhang R, Xu G, Zhang L, Wen W, Lu J, Liu J, Yu Y

PURPOSE: Allergic rhinitis (AR) is an inflammatory disorder of the upper airway. Exosomes or extracellular vesicles are nanosized vesicles of endosomal origin released from inflammatory and epithelial cells that have...
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Addition of Montelukast to Low-Dose Inhaled Corticosteroid Leads to Fewer Exacerbations in Older Patients Than Medium-Dose Inhaled Corticosteroid Monotherapy

Ye YM, Kim SH, Hur GY, Kim JH, Park JW, Shim JJ, Jung KS, Lee HY, Park HS, PRANA Group

PURPOSE: There have been few reports regarding the efficacy of antiasthmatics in older patients. To compare the efficacy of the addition of montelukast to low-dose inhaled budesonide (MON-400BUD) versus increasing...
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Challenges in the Management of Asthma in the Elderly

Song WJ, Cho SH

Recent literature has emphasized the clinical and socio-epidemiological significance of asthma in the elderly. However, why the disease burden remains high in this group is unclear. Elderly subjects usually have...
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Chronic Rhinosinusitis and the Coagulation System

Kim DY, Cho SH, Takabayashi T, Schleimer

Chronic rhinosinusitis (CRS) is one of the most common chronic diseases in adults and severely affects quality of life in patients. Although various etiologic and pathogenic mechanisms of CRS have...
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More Effective Strategies are Needed for Elderly Asthmatics in Real-World Practice

Song WJ, Jee YK

No abstract available.
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