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14 results

The First Case Series of Cryopyrin-Associated Periodic Syndrome in Korea

Han JH, Je YJ, Yoon HJ, Ahn JG, Lee JS, Park JW, Park HJ

  • Allergy Asthma Immunol Res.
  • 2019 Jul;11(4):583-588.
  • doi: 10.4168/aair.2019.11.4.583
Cryopyrin-associated periodic syndrome (CAPS) is a hereditary autoinflammatory syndrome caused by mutations in NLRP3 (encoding cryopyrin), which presents with fever, fatigue and arthralgia. Thus far, however there have been no...
Association of Sensitization to Different Aeroallergens With Airway Function and Nasal Patency in Urban Children

Lee S, Koh HY, Yon DK, Lee SW, Ha EK, Sung M, Lee KS, Jee HM, Sheen YH, Han MY

  • Allergy Asthma Immunol Res.
  • 2019 Jul;11(4):572-582.
  • doi: 10.4168/aair.2019.11.4.572
PURPOSE: Children with sensitization to aeroallergens have decreased lung function and nasal patency. Our purpose was to determine the association of sensitization to different aeroallergens with airway function and nasal...
Protease-Activated Receptors 2-Antagonist Suppresses Asthma by Inhibiting Reactive Oxygen Species-Thymic Stromal Lymphopoietin Inflammation and Epithelial Tight Junction Degradation

Kim HJ, Lee SH, Jeong S, Hong SJ

  • Allergy Asthma Immunol Res.
  • 2019 Jul;11(4):560-571.
  • doi: 10.4168/aair.2019.11.4.560
PURPOSE: Protease-activated receptor 2 (PAR2) reportedly triggers the immune response in allergic asthma. We aimed to investigate the mechanism on allergic inflammation mediated by PAR2. METHODS: Human lung epithelial cells (A549...
Combination Effect of Titrated Extract of Centella asiatica and Astaxanthin in a Mouse Model of Phthalic Anhydride-Induced Atopic Dermatitis

Park JH, Yeo IJ, Jang JS, Kim KC, Park MH, Lee HP, Han SB, Hong JT

  • Allergy Asthma Immunol Res.
  • 2019 Jul;11(4):548-559.
  • doi: 10.4168/aair.2019.11.4.548
PURPOSE: In our previous study, we demonstrated that both titrated extract of Centella asiatica (TECA) and astaxanthin (AST) have anti-inflammatory effects in a 5% phthalic anhydride (PA) mouse model of...
Cold Urticaria: Clinical Features and Natural Course in a Tropical Country

Kulthanan , Tuchinda P, Chularojanamontri L, Kiratiwongwan R

  • Allergy Asthma Immunol Res.
  • 2019 Jul;11(4):538-547.
  • doi: 10.4168/aair.2019.11.4.538
PURPOSE: To review the clinical features and natural courses of cold urticaria (ColdU) in a tropical country. METHODS: A retrospective chart review was performed of patients who visited Siriraj Urticaria Clinic,...
Underuse of Epinephrine for Pediatric Anaphylaxis Victims in the Emergency Department: A Population-based Study

Choi YJ, Kim J, Jung JY, Kwon H, Park JW

  • Allergy Asthma Immunol Res.
  • 2019 Jul;11(4):529-537.
  • doi: 10.4168/aair.2019.11.4.529
PURPOSE: Epinephrine is a key drug for treating anaphylaxis; however, its underuse is still a significant issue worldwide. The objective of this study was to compare epinephrine use between pediatric...
Add-on Tiotropium in Chinese Patients With Moderate Asthma: A Pooled Subgroup Analysis of MezzoTinA-Asthma 1 and 2

Lin J, Wan H, Kang J, Ma Q, Chen P, Jin M, Wang H, Liu S, Hao Q, Lin Y, Su L, Hu N

  • Allergy Asthma Immunol Res.
  • 2019 Jul;11(4):519-528.
  • doi: 10.4168/aair.2019.11.4.519
PURPOSE: Asthma affects approximately 30 million patients in China; however, tiotropium data for Chinese patients is limited. This study aimed to assess the efficacy and safety of tiotropium in Chinese...
Efficacy and Safety of Benralizumab for Korean Patients With Severe, Uncontrolled Eosinophilic Asthma

Park HS, Lee SH, Lee SY, Kim MK, Lee BJ, Werkström V, Barker P, Zangrilli

  • Allergy Asthma Immunol Res.
  • 2019 Jul;11(4):508-518.
  • doi: 10.4168/aair.2019.11.4.508
PURPOSE: In the Phase III SIROCCO trial (NCT01928771), benralizumab significantly reduced asthma exacerbations and improved lung function and symptoms for patients with severe, uncontrolled eosinophilic asthma. The aim of this...
Reduction Rate of Specific IgE Level as a Predictor of Persistent Egg Allergy in Children

Kim JD, Kim SY, Kwak EJ, Sol IS, Kim MJ, Kim YH, Kim KW, Sohn MH

  • Allergy Asthma Immunol Res.
  • 2019 Jul;11(4):498-507.
  • doi: 10.4168/aair.2019.11.4.498
PURPOSE: Egg is the most common food allergen in infants. However, the natural course of egg allergy has not been fully elucidated. This study aimed to describe clinical characteristics and...
Comparison of Corticosteroids by 3 Approaches to the Treatment of Chronic Rhinosinusitis With Nasal Polyps

Zhang Y, Lou H, Wang Y, Li Y, Zhang L, Wang C

  • Allergy Asthma Immunol Res.
  • 2019 Jul;11(4):482-497.
  • doi: 10.4168/aair.2019.11.4.482
PURPOSE: Corticosteroids are regarded as the mainstay of medical treatment of eosinophilic chronic rhinosinusitis with nasal polyps (ECRSwNP). To date, a head-to-head comparison of the efficacy and safety of glucocorticoid...
Emerging Therapies in Chronic Spontaneous Urticaria

Min TK, Saini SS

  • Allergy Asthma Immunol Res.
  • 2019 Jul;11(4):470-481.
  • doi: 10.4168/aair.2019.11.4.470
Chronic spontaneous urticaria (CSU) is characterized by typically short-lived and fleeting wheals, angioedema or both, which occur spontaneously and persist for longer than 6 weeks. This term is applied to...
House Dust Mite Allergy Under Changing Environments

Acevedo N, Zakzuk J, Caraballo

  • Allergy Asthma Immunol Res.
  • 2019 Jul;11(4):450-469.
  • doi: 10.4168/aair.2019.11.4.450
Environmental variations induced by industrialization and climate change partially explain the increase in prevalence and severity of allergic disease. One possible mechanism is the increase in allergen production leading to...
Clinical and Laboratory Predictors of Egg Allergy Resolution in Children

Kim JH

  • Allergy Asthma Immunol Res.
  • 2019 Jul;11(4):446-449.
  • doi: 10.4168/aair.2019.11.4.446
No abstract available.
What is the Optimal Method for Steroid Delivery in the Treatment of Chronic Rhinosinusitis With Nasal Polyps?

Hong SN, Kim DY

  • Allergy Asthma Immunol Res.
  • 2019 Jul;11(4):443-445.
  • doi: 10.4168/aair.2019.11.4.443
No abstract available.

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