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Cutaneous leukocytoclastic vasculitis due to anti-tuberculosis medications, rifampin and pyrazinamide

Kim JH, Moon JI, Kim JE, Choi GS, Park HS, Ye YM, Yim H

  • Allergy Asthma Immunol Res.
  • 2010 Jan;2(1):55-58.
  • doi: 10.4168/aair.2010.2.1.55
Anti-tuberculosis drugs frequently result in cutaneous adverse reactions, including pruritus, maculopapular exanthems, and urticaria. However, anti-tuberculosis drug-associated cutaneous leukocytoclastic vasculitis (CLV) has been rarely reported. We describe a case of...
Protection of leukotriene receptor antagonist against aspirin-induced bronchospasm in asthmatics

Park JS, Jang AS, Park SW, Lee YM, Uh ST, Kim YH, Cha JY, Park SM, Park CS

  • Allergy Asthma Immunol Res.
  • 2010 Jan;2(1):48-54.
  • doi: 10.4168/aair.2010.2.1.48
PURPOSE: Leukotriene receptor antagonists (LTRAs) are used to treat aspirin-intolerant asthma (AIA); however, the protective effects of long-term LTRA administration against aspirin-induced bronchospasm have not been evaluated. OBJECTIVES: We investigated the...
Chlamydophila pneumoniae enhances secretion of VEGF, TGF-beta and TIMP-1 from human bronchial epithelial cells under Th2 dominant microenvironment

Park CS, Kim TB, Moon KA, Bae YJ, Lee HR, Jang MK, Moon HB, Cho YS

  • Allergy Asthma Immunol Res.
  • 2010 Jan;2(1):41-47.
  • doi: 10.4168/aair.2010.2.1.41
PURPOSE: Chlamydophila pneumoniae infection in the airways is thought to be associated with the pathogenesis of asthma, especially in non-atopic severe asthma with irreversible airway obstruction that may be related...
Preventive effects of mycobacteria and their culture supernatants against asthma development in BALB/c mice

Han ER, Choi IS, Eom SH, Kim HJ

  • Allergy Asthma Immunol Res.
  • 2010 Jan;2(1):34-40.
  • doi: 10.4168/aair.2010.2.1.34
PURPOSE: Live Mycobacterium bovis Bacille Calmette-Guerin (BCG) has a suppressive effect on asthma, but its use in clinical practice may be limited due to adverse reactions. To develop a product...
Relationship between mode of delivery in childbirth and prevalence of allergic diseases in Korean children

Park YH, Kim KW, Choi BS, Jee HM, Sohn MH, Kim KE

  • Allergy Asthma Immunol Res.
  • 2010 Jan;2(1):28-33.
  • doi: 10.4168/aair.2010.2.1.28
PURPOSE: We tested the hypothesis that cesarean section might increase the risk for allergic diseases compared to vaginal delivery, by depriving the newborn of exposure to maternal microflora. METHODS: We evaluated...
Role of breast regression protein-39/YKL-40 in asthma and allergic responses

Lee CG, Elias JA

  • Allergy Asthma Immunol Res.
  • 2010 Jan;2(1):20-27.
  • doi: 10.4168/aair.2010.2.1.20
BRP-39 and its human homolog YKL-40 have been regarded as a prototype of chitinase-like proteins (CLP) in mammals. Exaggerated levels of YKL-40 protein and/or mRNA have been noted in a...
Pharmacogenetics of asthma in children

Kondo N, Matsui E, Nishimura , Kaneko H

  • Allergy Asthma Immunol Res.
  • 2010 Jan;2(1):14-19.
  • doi: 10.4168/aair.2010.2.1.14
Allergic diseases such as bronchial asthma and atopic dermatitis develop by a combination of genetic and environmental factors. Several candidate causative genes of asthma and atopy have been reported as...
Current guidelines for the management of asthma in young children

Potter PC

  • Allergy Asthma Immunol Res.
  • 2010 Jan;2(1):1-13.
  • doi: 10.4168/aair.2010.2.1.1
The diagnosis and management of asthma in young children is difficult, since there are many different wheezy phenotypes with varying underlying aetiologies and outcomes. This review discusses the different approaches...

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