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Aldosterone Rapidly Enhances Levels of the Striatin and Caveolin-1 Proteins in Rat Kidney: The Role of the Mineralocorticoid Receptor

Inthachart K, Manotham K, Eiam-Ong S, Eiam-Ong S

BACKGROUND: Striatin and caveolin-1 (cav-1) are scaffolding/regulating proteins that are associated with salt-sensitive high blood pressure and promote renal sodium and water reabsorption, respectively. The mineralocorticoid receptor (MR) interacts with...
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Update on the Aldosterone Resolution Score and Lateralization in Patients with Primary Aldosteronism

Cho EH

No abstract available.
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Emerging Role of Aldosterone in Mediating the Vicious Cycle of Obesity, Insulin Resistance and Metabolic Syndrome

Park S

No abstract available.
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Independent Association of Serum Aldosterone Level with Metabolic Syndrome and Insulin Resistance in Korean Adults

Min SH, Kim SH, Jeong IK, Cho HC, Jeong JO, Lee JH, Kang HJ, Kim HS, Park KS, Lim S

BACKGROUND AND OBJECTIVES: A relationship between renin-angiotensin system (RAS) components and metabolic syndrome (MetS) has been suggested, but not elucidated clearly. We examined the levels of RAS components in patients...
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CTNNB1 Mutation in Aldosterone Producing Adenoma

Wang JJ, Peng KY, Wu VC, Tseng FY, Wu KD

Discoveries of somatic mutations permit the recognition of subtypes of aldosterone-producing adenomas (APAs) with distinct clinical presentations and pathological features. Catenin β1 (CTNNB1) mutation in APAs has been recently described...
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Implications of Plasma Renin Activity and Plasma Aldosterone Concentration in Critically Ill Patients with Septic Shock

Chung KS, Song JH, Jung WJ, Kim YS, Kim SK, Chang J, Park MS

BACKGROUND: The renin-angiotensin-aldosterone system is closely associated with volume status and vascular tone in septic shock. The present study aimed to assess whether plasma renin activity (PRA) and plasma aldosterone...
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Bilateral Adrenocortical Masses Producing Aldosterone and Cortisol Independently

Lee SE, Kim JH, Lee YB, Seok H, Shin IS, Eun YH, Kim JH, Oh YL

A 31-year-old woman was referred to our hospital with symptoms of hypertension and bilateral adrenocortical masses with no feature of Cushing syndrome. The serum aldosterone/renin ratio was elevated and the...
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Incidentally Discovered Aldosterone and Cortisol Cosecreting Adrenal Cortical Adenoma

Bae JY, Lee J, Han Y, Min SK, Cho MS, Sung YA

A substantial proportion of adrenal incidentalomas demonstrates subtle hormonal hypersecretion; however, adenomas that cosecrete aldosterone and cortisol are rare. We here report a case of an adrenal mass that was...
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Effect of aldosterone on epithelial-to-mesenchymal transition of human peritoneal mesothelial cells

Yu M, Shin HS, Lee HK, Ryu DR, Kim SJ, Choi KB, Kang DH

BACKGROUND: Peritoneal fibrosis is one of the major causes of technical failure in patients on peritoneal dialysis. Epithelial-to-mesenchymal transition (EMT) of the peritoneum is an early and reversible mechanism of...
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Management of a 25-day-old Male Presenting with a First Episode of Acute Pyelonephritis, and Persistent Hyperkalemia with Normal Serum Aldosterone

Kang YS, Choi JY, Lee JH

Hyperkalemia is often detected in young infants, particularly in association with acute pyelonephritis or a urinary tract anomaly. Cases of hyperkalemia in this population may also be due to transient...
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Regulation of AQP2 in Collecting Duct: An emphasis on the Effects of Angiotensin II or Aldosterone

Lee BH, Kwon TH

Vasopressin, angiotensin II (AngII), and aldosterone are essential hormones in the regulation of body fluid homeostatsis. We examined the effects of AngII or aldosterone on the regulation of body water...
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Aldosterone as a Cardiovascular Risk Factor

Yoo SJ

No abstract available.
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Aldosterone Receptor Blockade Prevents Inflammatory Reaction on Type 2 Diabetic Nephropathy

Han SY, Kim CH, Ji YH, Han KH, Kang YS, Cha DR, Kim HS

  • KMID: 2307229
  • Korean J Nephrol.
  • 2005 Sep;24(5):691-698.
BACKGROUND: Aldosterone induces renal injury independent of angiotensin II. This harmful effect might be mediated via inflammatory reaction. Aldosterone receptor blockade can retard renal damage in various renal diseases including...
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Interaction of Pituitary Adenylate Cyclase-Activating Polypeptide and Angiotensin II on Aldosterone Production in Human Adrenocortical H295R Cells

Kim SY, Kim SW, Cho YM, Park DJ, Shin CS, Park KS, Cho BY, Lee HK

  • KMID: 2200306
  • J Korean Soc Endocrinol.
  • 2003 Jun;18(3):272-282.
BACKGROUND: Evidence is accumulating that aldosterone secretion can be regulated in a paracrine and/or an autocrine manner by several neuropeptides locally released within the adrenal gland. Among neuropeptides, pituitary adenylate...
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The Relationship between the Upright Serum aldosterone Level and the Left Ventricular Geometry in Essentioal Hypertension

shin JH, Lee BH, Oh JK, Choi HJ, Lee S, kim MK, Jung KT, Park SC, Lee CK

  • KMID: 2026099
  • J Korean Soc Echocardiogr.
  • 2002 Jun;10(1):58-64.
BACKGROUND: Aldosterone acts as a non-hemodynamic factors on the hypertensive heart regarding sodium retension or myocardial fibrosis. To elucidate whether aldosterone is associated with the specific left ventricular geometry or...
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Enhanced Expression of Aldosterone Synthase and Adrenomedullin in Left and Right Ventricular Hypertrophy in Rats

Lee JU, Lee S, Kim S, Lee WJ

  • KMID: 1615003
  • Korean J Physiol Pharmacol.
  • 2002 Apr;6(2):121-126.
The pathophysiological implications of aldosterone and adrenomedullin in the cardiac ventricular hypertrophy were examined. Male Sprague-Dawley rats were treated with deoxycorticosterone acetate (DOCA)-salt and monocrotaline (MCT) to selectively elicit left...
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The Effects of an Aldosterone Synthase (CYP11B2) Gene Polymorphism on the Risk of Myocardial Infarction

Ryu SK, Park HY, Im EK, Yoon YW, Jang Y, Yoon YW, Shim WH, Cho SY

BACKGROUND AND OBJECTIVES: Several polymorphisms of the renin-angiotensin-aldosterone system have been found to have pleiotropic effects on cardiovascular diseases. Polymorphism of the aldosterone synthase gene (CYP11B2), which may influence plasma...
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The Role of Aldosterone on the Development of Renal Tubular Reabsorption in Low Birth Weight Infants

Choi BM, Koo HK, Yook JW, Kim KB, Jang GY, Kim MH, Yoo KH, Hong YS, Lee JW, Kim SK

  • KMID: 1829874
  • J Korean Pediatr Soc.
  • 2001 Nov;44(11):1233-1242.
PURPOSE: To determine the postnatal changes in aldosterone action on the renal tubular reabsorption in low birth weight(LBW) infants, we assessed the relation of the aldosterone concentrations to renal parameters...
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The Effects of Aldosterone and Cytokines IL-1beta, TNF-alpha on the Expression of Angiotensin Converting Enzyme Gene in Vascular Smooth Muscle Cells

Kim DK, Huh JE, Choe YH, Park SJ, Jung EA, Byun J, Gwon HC, Park SW, Kim JS, Lee SH, Hong KP, Park JE, Seo JD, Lee WR

BACKGROUND: It has been suggested that all components of the renin-angiotensin-aldosterone system (RAAS) are present in the vascular wall and that the vascular RAAS modulates vascular tone and vascular...
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Primary Aldosteronism Due to Aldosterone Producing Adenama in the Presence of Contralateral Nonfunctioning Adenama

Son HY, Kim EA, Kwon JI, Kim YJ, Chung WH, Choi KR, Choi SJ, Park HY, Kang MH

  • KMID: 2142209
  • J Korean Soc Endocrinol.
  • 1998 Jun;13(2):223-229.
Primary aldosteronism is in most cases due either to a unilateral adrenal adenama or to a bilateral hyperplasia of the adrenal cortex. But, a few of bilateral adrena1 tumors in...
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