- Effect of phosphorus deficiency on erythrocytic morphology and function in cows
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Zhang Z, Bi M, Yang J, Yao H, Liu Z, Xu S
- KMID: 2412451
- J Vet Sci.
- 2017 Sep;18(3):333-340.
- doi: 10.4142/jvs.2017.18.3.333
The aim of this study was to evaluate the influence of phosphorus (P) deficiency on the morphological and functional characteristics of erythrocytes in cows. Forty Holstein-Friesian dairy cows in mid-lactation... -
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- Entecavir to Telbivudine Switch Therapy in Entecavir-Treated Patients with Undetectable Hepatitis B Viral DNA
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Kim DH, Choi JW, Seo JH, Cho YS, Won SY, Park BK, Jeon HH, Shin SY, Lee CK
- KMID: 2419112
- Yonsei Med J.
- 2017 May;58(3):552-556.
- doi: 10.3349/ymj.2017.58.3.552
PURPOSE: This study examined 2-year outcome of consecutive therapy using entecavir (ETV) followed by telbivudine (LdT) in subjects with undetectable hepatitis B virus (HBV) DNA level and normal alanine aminotransferase... -
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- Efficacy of switching from adefovir to tenofovir in chronic hepatitis B patients who exhibit suboptimal responses to adefovir-based combination rescue therapy due to resistance to nucleoside analogues (SATIS study)
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Lee HW, Park JY, Kim BK, Kim MY, Lee JI, Kim YS, Yoon KT, Han KH, Ahn SH
- KMID: 2373148
- Clin Mol Hepatol.
- 2016 Dec;22(4):443-449.
- doi: 10.3350/cmh.2016.0037
BACKGROUND/AIMS: It remains to be determined whether switching from adefovir (ADV) to tenofovir (TDF) provides better virological outcomes in patients exhibiting suboptimal responses to ADV plus nucleoside analogue (ADV+NA) therapy... -
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- A Korean patient with Guillain-Barré syndrome following acute hepatitis E whose cholestasis resolved with steroid therapy
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Ji SB, Lee SS, Jung HC, Kim HJ, Kim HJ, Kim TH, Jung WT, Lee OJ, Song DH
- KMID: 2373141
- Clin Mol Hepatol.
- 2016 Sep;22(3):396-399.
- doi: 10.3350/cmh.2015.0039
Autochthonous hepatitis E virus (HEV) is an emerging pathogen in developed countries, and several cases of acute HEV infection have been reported in South Korea. However, there have been no... -
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- Hepatitis B surface antigen titer is a good indicator of durable viral response after entecavir off-treatment for chronic hepatitis B
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Lee HA, Seo YS, Park SW, Park SJ, Kim TH, Suh SJ, Jung YK, Kim JH, An H, Yim HJ, Yeon JE, Byun KS, Um SH
- KMID: 2373139
- Clin Mol Hepatol.
- 2016 Sep;22(3):382-389.
- doi: 10.3350/cmh.2016.0047
BACKGROUND/AIMS: Clear indicators for stopping antiviral therapy in chronic hepatitis B (CHB) patients are not yet available. Since the level of hepatitis B surface antigen (HBsAg) is correlated with covalently... -
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- Comparison of the clinical outcomes between antiviral-naïve patients treated with entecavir and lamivudine-resistant patients receiving adefovir add-on lamivudine combination treatment
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Kim HJ, Park SK, Yang HJ, Jung YS, Park JH, Park DI, Cho YK, Sohn CI, Jeon WK, Kim BI, Choi KY
- KMID: 2373135
- Clin Mol Hepatol.
- 2016 Sep;22(3):350-358.
- doi: 10.3350/cmh.2016.0019
BACKGROUND/AIMS: To analyze the effects of preexisting lamivudine (LAM) resistance and applying antiviral treatment (adefovir [ADV] add-on LAM combination treatment) on long-term treatment outcomes, and comparing the clinical outcomes of... -
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- Efficacy and safety of daclatasvir and asunaprevir for hepatitis C virus genotype 1b infection
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Nam HC, Lee HL, Yang H, Song MJ
- KMID: 2373122
- Clin Mol Hepatol.
- 2016 Jun;22(2):259-266.
- doi: 10.3350/cmh.2016.0020
BACKGROUND/AIMS: The treatment strategy for hepatitis C virus (HCV) has been changing rapidly since the introduction of direct-acting antivirals such as daclatasvir (DCV) and asunaprevir (ASV). We evaluated the efficacy... -
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- Comparative Analysis of Liver Injury-Associated Cytokines in Acute Hepatitis A and B
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Shin SY, Jeong SH, Sung PS, Lee J, Kim HJ, Lee HW, Shin EC
- KMID: 2374085
- Yonsei Med J.
- 2016 May;57(3):652-657.
- doi: 10.3349/ymj.2016.57.3.652
PURPOSE: Acute hepatitis A (AHA) and acute hepatitis B (AHB) are caused by an acute infection of the hepatitis A virus and the hepatitis B virus, respectively. In both AHA... -
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- Prevalence and Factors Associated with Nonalcoholic Fatty Liver Disease in a Nonobese Korean Population
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Cho HC
- KMID: 2382352
- Gut Liver.
- 2016 Jan;10(1):117-125.
- doi: 10.5009/gnl14444
BACKGROUND/AIMS: Nonalcoholic fatty liver disease (NAFLD) is an emerging problem in Asia, but little is known about the disease in the nonobese population. The aims of this study were to... -
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- Doxazosin Treatment Attenuates Carbon Tetrachloride-Induced Liver Fibrosis in Hamsters through a Decrease in Transforming Growth Factor beta Secretion
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Munoz-Ortega MH, Llamas-Ramirez RW, Romero-Delgadillo NI, Elias-Flores TG, de Jesus Tavares-Rodriguez E, del Rosario Campos-Esparza M, Cervantes-Garcia D, Munoz-Fernandez L, Gerardo-Rodriguez M, Ventura-Juarez J
- KMID: 2382350
- Gut Liver.
- 2016 Jan;10(1):101-108.
- doi: 10.5009/gnl14459
BACKGROUND/AIMS: The development of therapeutic strategies for the treatment of cirrhosis has become an important focus for basic and clinical researchers. Adrenergic receptor antagonists have been evaluated as antifibrotic drugs... -
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- Early monitoring for detection of antituberculous drug-induced hepatotoxicity
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Lee CM, Lee SS, Lee JM, Cho HC, Kim WS, Kim HJ, Ha CY, Kim HJ, Kim TH, Jung WT, Lee OJ
- KMID: 2373774
- Korean J Intern Med.
- 2016 Jan;31(1):65-72.
- doi: 10.3904/kjim.2016.31.1.65
BACKGROUND/AIMS: We investigated the time of onset of antituberculous drug-induced hepatotoxicity (ADIH) and related characteristics. METHODS: Adult patients (n = 1,031) treated with first-line antituberculous drugs between February 2009 and January... -
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- Clinical Features of Drug-induced Liver Injury According to Etiology
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Lee BM, Lee WC, Jang JY, Ahn P, Kim JN, Jeong SW, Park EJ, Lee SH, Kim SG, Cha SW, Kim YS, Cho YD, Kim HS, Kim BS
- KMID: 2359966
- J Korean Med Sci.
- 2015 Dec;30(12):1815-1820.
- doi: 10.3346/jkms.2015.30.12.1815
Drug-induced liver injury (DILI) is an increasingly common cause of acute hepatitis. We examined clinical features and types of liver injury of 65 affected patients who underwent liver biopsy according... -
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- Effect of vitamin E in nonalcoholic fatty liver disease with metabolic syndrome: A propensity score-matched cohort study
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Kim GH, Chung JW, Lee JH, Ok KS, Jang ES, Kim J, Shin CM, Park YS, Hwang JH, Jeong SH, Kim N, Lee DH, Kim JW
- KMID: 2359820
- Clin Mol Hepatol.
- 2015 Dec;21(4):379-386.
- doi: 10.3350/cmh.2015.21.4.379
BACKGROUND/AIMS: Vitamin E improves the biochemical profiles and liver histology in nonalcoholic steatohepatitis, but the role of vitamin E is not clearly defined in the management of nonalcoholic fatty liver... -
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- Hepatitis B Surface Antigen Quantification across Different Phases of Chronic Hepatitis B Virus Infection Using an Immunoradiometric Assay
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Chung KH, Kim W, Kim BG, Lee HY, Jin E, Cho Y, Seo JY, Kim HY, Jung YJ, Kim JW, Jeong JB, Lee KL
- KMID: 2234073
- Gut Liver.
- 2015 Sep;9(5):657-664.
- doi: 10.5009/gnl14188
BACKGROUND/AIMS: Quantification of hepatitis B surface antigen (HBsAg) is an emerging serologic test and may be useful for identifying treatment strategies for chronic hepatitis B (CHB). This study aimed to... -
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- Liver dysfunction induced by systemic hypersensitivity reaction to lamotrigine: case report
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Im SG, Yoo SH, Park YM, Lee SJ, Jang SK, Jeon DO, Cho HJ, Oh MJ
- KMID: 2164369
- Clin Mol Hepatol.
- 2015 Jun;21(2):180-182.
- doi: 10.3350/cmh.2015.21.2.180
Lamotrigine is an anticonvulsant drug used to treat partial and generalized seizure disorders. Hypersensitivity to lamotrigine usually causes mild symptoms such as fever, rash, and slight invasion of internal organs.... -
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- IL28B Is Associated with Outcomes of Chronic HBV Infection
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Shi X, Chi X, Pan Y, Gao Y, Li W, Yang C, Zhong J, Xu D, Zhang M, Minuk G, Jiang J, Niu J
- KMID: 2450334
- Yonsei Med J.
- 2015 May;56(3):625-633.
- doi: 10.3349/ymj.2015.56.3.625
PURPOSE: The role of IL28B gene variants and expression in hepatitis B virus (HBV) infections are not well understood. Here, we evaluated whether IL28B gene expression and rs12979860 variations are... -
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- Physical Activity- and Alcohol-dependent Association Between Air Pollution Exposure and Elevated Liver Enzyme Levels: An Elderly Panel Study
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Kim KN, Lee H, Kim JH, Jung K, Lim YH, Hong YC
- KMID: 2381464
- J Prev Med Public Health.
- 2015 May;48(3):151-169.
- doi: 10.3961/jpmph.15.014
OBJECTIVES: The deleterious effects of air pollution on various health outcomes have been demonstrated. However, few studies have examined the effects of air pollution on liver enzyme levels. METHODS: Blood samples... -
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- Alteration of laboratory findings after radiofrequency ablation of hepatocellular carcinoma: relationship to severity of the underlying liver disease and the ablation volume
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Shin SW, Jeong WK, Lim S, Kim Y, Kim J
- KMID: 2155293
- Clin Mol Hepatol.
- 2015 Mar;21(1):71-79.
- doi: 10.3350/cmh.2015.21.1.71
BACKGROUND/AIMS: To investigate sequential changes in laboratory markers after radiofrequency ablation (RFA) of hepatocellular carcinoma (HCC) and the relationship of these changes to the severity of the underlying liver disease. METHODS:... -
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- The factors associated with longitudinal changes in liver stiffness in patients with chronic hepatitis B
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Yo IK, Kwon OS, Park JW, Lee JJ, Lee JH, Won IS, Na SY, Jang PK, Park PH, Choi DJ, Kim YS, Kim JH
- KMID: 2155289
- Clin Mol Hepatol.
- 2015 Mar;21(1):32-40.
- doi: 10.3350/cmh.2015.21.1.32
BACKGROUND/AIMS: Liver stiffness (LS) as assessed by transient elastography (TE) can change longitudinally in patients with chronic hepatitis B (CHB). The aim of this study was to identify the factors... -
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- Drug-induced Hepatotoxicity of Anti-tuberculosis Drugs and Their Serum Levels
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Jeong I, Park JS, Cho YJ, Yoon HI, Song J, Lee CT, Lee JH
- KMID: 2129647
- J Korean Med Sci.
- 2015 Feb;30(2):167-172.
- doi: 10.3346/jkms.2015.30.2.167
The correlation between serum anti-tuberculosis (TB) drug levels and the drug-induced hepatotoxicity (DIH) remains unclear. The purpose of this study was to investigate whether anti-TB DIH is associated with basal... -
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