- The Mechanism of White and Brown Adipocyte Differentiation
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Nakagami H
- KMID: 2280709
- Diabetes Metab J.
- 2013 Apr;37(2):85-90.
- doi: 10.4093/dmj.2013.37.2.85
Obesity gives vent to many diseases such as type 2 diabetes, hypertension, and hyperlipidemia, being considered as the main causes of mortality and morbidity worldwide. The pathogenesis and pathophysiology of... -
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- Food Intake and Thermogenesis in Adipose Tissue
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Goto T, Kim M, Takahashi , Takahashi , Kawada T
- KMID: 2357088
- Korean J Obes.
- 2016 Sep;25(3):109-114.
- doi: 10.7570/kjo.2016.25.3.109
Brown adipose tissue (BAT) is regarded as a key target for developing interventions to prevent and treat obesity and age-related diseases. In addition, uncoupling pro tein 1 (UCP1) - expressing... -
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- Brown Fat and Browning for the Treatment of Obesity and Related Metabolic Disorders
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Kim SH, Plutzky J
- KMID: 2383310
- Diabetes Metab J.
- 2016 Feb;40(1):12-21.
- doi: 10.4093/dmj.2016.40.1.12
Brown fat is a specialized fat depot that can increase energy expenditure and produce heat. After the recent discovery of the presence of active brown fat in human adults and... -
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- Eosinophils and Type 2 Cytokine Signaling in Macrophages Support the Biogenesis of Cold-induced Beige Fat
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Jung Y
- KMID: 2168742
- J Bacteriol Virol.
- 2016 Mar;46(1):44-46.
- doi: 10.4167/jbv.2016.46.1.44
Brown adipose generates heat via oxidation of fatty acids by a mitochondrial uncoupling protein 1 (UCP1)-dependent process. In addition, a subpopulation of cells within subcutaneous white adipose tissue, known as... -
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- Brown Adipose Tissue as a Therapeutic Target for Obesity: From Mice to Humans
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Saito M
- KMID: 2271146
- Korean J Obes.
- 2015 Mar;24(1):1-8.
- doi: 10.7570/kjo.2015.24.1.1
Brown adipose tissue (BAT) is a site of sympathetically activated non-shivering thermognenesis during cold exposure and after spontaneous hyperphagia, thereby involving in the autonomic regulation of energy balance and body... -
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- HOXC10 suppresses browning of white adipose tissues
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Ng Y, Tan SX, Chia SY, Tan HY, Gun SY, Sun L, Hong W, Han W
- KMID: 2375022
- Exp Mol Med.
- 2017 Feb;49(2):e292.
- doi: 10.1038/emm.2016.144
Given that increased thermogenesis in white adipose tissue, also known as browning, promotes energy expenditure, significant efforts have been invested to determine the molecular factors involved in this process. Here... -
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- Brown Adipose Tissue as a Regulator of Energy Expenditure and Body Fat in Humans
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Saito M
- KMID: 2280738
- Diabetes Metab J.
- 2013 Feb;37(1):22-29.
- doi: 10.4093/dmj.2013.37.1.22
Brown adipose tissue (BAT) is recognized as the major site of sympathetically activated nonshivering thermogenesis during cold exposure and after spontaneous hyperphagia, thereby controling whole-body energy expenditure and body fat.... -
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- Recent advance in brown adipose physiology and its therapeutic potential
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Lee YH, Jung YS, Choi D
- KMID: 2155343
- Exp Mol Med.
- 2014 Feb;46(2):e78.
- doi: 10.1038/emm.2013.163
Brown adipose tissue (BAT) is a specialized thermoregulatory organ that has a critical role in the regulation of energy metabolism. Specifically, energy expenditure can be enhanced by the activation of... -
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- Hibernoma of Right Shoulder :A Case Report
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Kang HJ, Hwang BH, Jung M, Koo JS, Shin KH, Hahn SB, Kim SJ
- KMID: 2101897
- J Korean Shoulder Elbow Soc.
- 2009 Jun;12(1):94-97.
PURPOSE: Hibernoma is a very rare benign soft tissue tumor of the hypervascularized brown fat tissue with no malignant potential. MATERIALS AND METHODS: However, it is difficult to differentiate a hibernoma... -
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- (99m)Tc-MIBI Uptake in a Thyroid Adenoma with Diffuse Adipose Metaplasia
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Paone G, Mazzucchelli L, Peloni G, Fasolini F, Giovanella L
- KMID: 2386162
- Nucl Med Mol Imaging.
- 2016 Dec;50(4):362-364.
- doi: 10.1007/s13139-015-0383-8
A 71-year-old female underwent a (99m)Tc- MIBI scan to characterize a cold nodule (30 mm) of the left thyroid lobe. The nodule showed diffuse uptake and retention of the radiotracer.... -
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- Quantification of Fat Concentration and Vascular Response in Brown and White Adipose Tissue of Rats by Spectral CT Imaging
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Peng XG, Zhao Z, Chang D, Bai Y, Xu Q, Ju S
- KMID: 2471642
- Korean J Radiol.
- 2020 Feb;21(2):248-256.
- doi: 10.3348/kjr.2019.0111
OBJECTIVE: The purpose of the study was to non-invasively characterize and discriminate brown adipose tissue (BAT) from white adipose tissue (WAT) in rats using spectral computed tomography (CT) with histological... -
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- Induction of thermogenic adipocytes: molecular targets and thermogenic small molecules
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Song NJ, Chang SH, Li DY, Villanueva CJ, Park KW
- KMID: 2388351
- Exp Mol Med.
- 2017 Jul;49(7):e353.
- doi: 10.1038/emm.2017.70
Adipose tissue is a central metabolic organ that controls energy homeostasis of the whole body. White adipose tissue (WAT) stores excess energy in the form of triglycerides, whereas brown adipose... -
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- Changes of Lipogenic and Lipolytic Activities Following Repeated Fasting and Refeeding in Rat
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Lee CK, Kim YW
- KMID: 2078200
- Korean J Obes.
- 2005 Mar;14(1):16-21.
BACKGROUND: It is known that repeated fasting and refeeding increase capacity of fat storage in adipose tissue as an adaptive response to fasting. However, the amount of weight gain in... -
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- A case of hibernoma arising in the scalp
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Kim HY, Kim HU, Ihm CW
- KMID: 1693131
- Korean J Dermatol.
- 1992 Apr;30(2):258-261.
Hibernoma is a rare subcutaneous neoplasm resembling the brown fat of the hibernating animal. It is usually found in the interscapular, cervical or axillary regions. We report a case of... -
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- Effects of Caspsaicin on Thermoregulation of Interscapular Brown Adipose Tissue in Rats
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Lee TH, Chang HJ, Park BJ, Osaka T, Inoue S
- KMID: 2275033
- Chonnam Med J.
- 1997 Dec;33(2):265-270.
This Studied included observation of effects of capsaicin on thermogenesis of interscapular bwown adipose tissue of male Wistar rats. And the results were as follows. 1. Capsaicin(5mg/kg, S.C.) increased temperature... -
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- The Impact of Childhood Obesity on Skeletal Health and Development
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Dimitri P
- KMID: 2452622
- J Obes Metab Syndr.
- 2019 Mar;28(1):4-17.
- doi: 10.7570/jomes.2019.28.1.4
Increased risk of fracture identified in obese children has led to a focus on the relationship between fat, bone, and the impact of obesity during skeletal development. Early studies have... -
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- New Therapeutic Targets for Obesity Treatment in Basic Medical Science
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Lee SK
- KMID: 1437229
- Korean J Obes.
- 2012 Sep;21(3):125-131.
- doi: 10.7570/kjo.2012.21.3.125
Change in either energy intake or energy expenditure alone will meet resistance as compensatory adjustments occur, because body fat seems to be regulated homeostatically. Therefore, combined therapy targeting the multiple... -
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- Skeletal Muscle Thermogenesis and Its Role in Whole Body Energy Metabolism
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Periasamy , Herrera JL, Reis FC
- KMID: 2392475
- Diabetes Metab J.
- 2017 Oct;41(5):327-336.
- doi: 10.4093/dmj.2017.41.5.327
Obesity and diabetes has become a major epidemic across the globe. Controlling obesity has been a challenge since this would require either increased physical activity or reduced caloric intake; both... -
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- The Prevalence and Characteristics of Brown Adipose Tissue in an (18)F-FDG PET Study of Koreans
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Park JY, Lim JS, Park EY, Cho AR, Kim BI, Cheon GJ, Choi CW, Lim SM
- KMID: 1455397
- Nucl Med Mol Imaging.
- 2010 Sep;44(3):207-212.
PURPOSE: The object of this study was to evaluate the prevalence and characteristics of brown adipose tissue (BAT) in Korean subjects using (18)F-fluorodeoxyglucose positron emission tomography ((18)F-FDG PET). METHODS: Six thousand... -
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- Effects of caloric restriction on the expression of lipocalin-2 and its receptor in the brown adipose tissue of high-fat diet-fed mice
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Park KA, Jin Z, An HS, Lee JY, Jeong EA, Choi EB, Kim KE, Shin HJ, Lee JE, Roh GS
- KMID: 2455810
- Korean J Physiol Pharmacol.
- 2019 Sep;23(5):335-344.
- doi: 10.4196/kjpp.2019.23.5.335
Obesity causes inflammation and impairs thermogenic functions in brown adipose tissue (BAT). The adipokine lipocalin 2 (LCN2) has been implicated in inflammation and obesity. Herein, we investigated the protective effects... -
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