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Disulfram Treatment of NUP98-PHF23 AML Is Not Effective In Vivo: Potential Role for Hematopoietic Stem Cells Niche

Park ES, Chung YJ, Aplan PD

BACKGROUND: NUP98 has numerous partner genes of which plant homeodomain (PHD) finger protein 23 (PHF23) fusion with NUP98 (NP23) can be detected by RT-PCR in patients with cytogenetically normal acute...
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Brachial Plexopathy due to Myeloid Sarcoma in a Patient With Acute Myeloid Leukemia After Allogenic Peripheral Blood Stem Cell Transplantation

Ha Y, Sung DH, Park Y, Kim DH

Myeloid sarcoma is a solid, extramedullary tumor comprising of immature myeloid cells. It may occur in any organ; however, the invasion of peripheral nervous system is rare. Herein, we report...
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Second Primary Glioblastoma Multiforme Following Autologous Hematopoietic Stem Cell Transplantation in a Patient with Acute Myelogenous Leukemia

Kim EO, Kim HJ, Eom KS, Cho BS, Lee SE, Yahng SA, Lee JW, Min WS

  • KMID: 2167558
  • Cancer Res Treat.
  • 2011 Sep;43(3):195-198.
Glioblastoma multiforme (GM) is one of the most aggressive primary brain tumors, and has a poor prognosis despite intensive treatment. GM is also the most malignant astrocytoma, with histopathological features...
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The Effectiveness of Once-daily Intravenous Busulfan as a Conditioning Regime for Hematopoietic Stem Cell Transplantation in Children with Acute Myelogenous Leukemia

Park SS, Kwak JW, Lim YT

BACKGROUND: There have recently been some reports suggesting that once-daily intravenous busulfan (IV Bu) as a conditioning regime for hematopoietic stem cell transplantation (HSCT) possibly reduces the toxicities without influencing...
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Tetrasomy 8 in a Patient with Acute Monoblastic Leukemia

Kim J, Park TS, Song J, Lee KA, Lee SG, Cheong JW, Choi JR

Trisomy 8 is one of the most frequent numerical chromosomal abnormalities observed in hematological malignancies, whereas tetrasomy 8 is a clonal aberration seen mainly in myeloid disorders such as acute...
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A Case of Reversible Posterior Leukoencephalopathy Syndrome associated with Low dose Intravenous Immunoglobulin Therapy after Induction Chemotherapy in Acute Myeloid Leukemia

Lee KO, Na SJ, Lee JY, Yum KS

  • KMID: 2343316
  • J Korean Neurol Assoc.
  • 2008 Feb;26(1):78-80.
No abstract available.
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Clinical Significance of Quantitation of WT1 Gene Expression for Minimal Residual Disease Monitoring of Acute Myelogenous Leukemia

Kim HR, Shin JH, Lee JN, Lee EY

BACKGROUND: Following induction chemotherapy for AML, a sensitive determination of minimal residual disease (MRD) in patients achieving complete remission (CR) should enable the detection of early relapse. This study...
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Multiple Intracranial Tuberculomas Mimicking Granulocytic Sarcomas in Acute Myeloid Leukemia

Ahn JS, Yang DH, Kim YK, Cho SH, Kim IY, Lee JJ, Chung IJ, Kim HJ

The diagnosis of incracranial tuberculoma in immune-compromised hosts is often difficult because conventional magnetic resonance (MR) imaging of tuberculoma reveals various findings and neurologic symptoms are not typical. Here, we...
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Prevalence of FLT3 Internal Tandem Duplication in Adult Acute Myelogenous Leukemia

Lee JN, Kim HR, Shin JH, Joo YD

BACKGROUND: fms-like tyrosine kinase (FLT3), a member of the class III receptor tyrosine kinases, regulates the proliferation and differentiation of hematopoietic stem cells. An internal tandem duplication of the...
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Three cases of Philadelphia (Ph) chromosome positive acute myeloid leukemia (AML) treated with imatinib mesylate (Glivec, STI571) and allogeneic hematopoietic stem cell transplantation after induction chemotherapy

Yoon JH, Kim HJ, Nam HS, Park YJ, Eom KS, Min WS, Kim CC

  • KMID: 2256446
  • Korean J Med.
  • 2007 Mar;72(3):326-330.
The Ph-chromosome is the hallmark of chronic myelogenous leukemia (CML), but it has also been reported infrequently for de novo AML. This cytogenetic variant of AML is characterized by a...
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A Case of Leukemia Cutis Presenting with Extensive Nodular Lesions

Kang BS, Choi HJ, Park HJ, Lee JY, Cho BK

  • KMID: 2248909
  • Korean J Dermatol.
  • 2006 Dec;44(12):1448-1450.
Leukemia cutis, the specific infiltration of leukemic cells, can be seen in any leukemia, but are especially common in the acute myelogenous leukemia M4 and M5 variants. We herein report...
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Tuberculous Lymphadenitis in Patients with Myelogenous Leukemia

Lee CS, Song JS, Choe PG, Cho JH, Bang JW, Park KH, Park WB, Kim HB, Kim NJ, Yoon SS, Park S, Kim BK, Oh MD, Choe KW

  • KMID: 2054318
  • Infect Chemother.
  • 2006 Oct;38(5):266-270.
During the neutropenic phase, leukemia patients receiving chemotherapy are prone to bacterial and, fungal infections; occasionally mycobacterial, viral and protozoal organisms may also cause infections. Mycobacterium tuberculosis infection was reported...
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Reduced-intensity Umbilical Cord Blood Transplantation in Adult Acute Myeloid Leukemia: Report of Four Cases

Chong SY, Jang MJ, Kang MS, Baek JY, Chang SK, Choi YK, Oh D

The outcome after unrelated cord blood transplantation (CBT) is similar to that of matched unrelated bone marrow transplantation in children, and the results of CBT in adult patients has recently...
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A Case of Concurrent Acute Myelogenous Leukemia and Retroperitoneal Teratoma in an Infant

Park SS, Park HS, Lee CH, Lee EY, Lim YT

  • KMID: 2049212
  • Clin Pediatr Hematol Oncol.
  • 2006 Apr;13(1):55-59.
Most hematologic malignancies occurring in a patient with a malignant solid tumor are secondary leukemia developing as complications after chemotherapy or radiotherapy. On the other hand, it is very rare...
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Acute myelogenous leukemia in the elderly (>or=60): retrospective study of 115 patients

Shin HC, Na II, Yun T, Lee KW, Song EG, Choi IS, Oh DY, Kim JH, Lee JS, Yoon SS, Park S, Kim BK, Kim NK

  • KMID: 2081194
  • Korean J Med.
  • 2006 Feb;70(2):196-206.
BACKGROUND: Acute myelogenous leukemia (AML) is frequently encountered in elderly patients whereas intensive chemotherapy yield lower rate of complete remission (CR) and survival than young patients. This study was aimed...
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A Case of Acute Erythroleukemia in a Human Immunodeficiency Virus-Infected Patient

Yi J, Lee DS, Park MH, Cho HI

  • KMID: 2305419
  • Korean J Lab Med.
  • 2005 Dec;25(6):385-388.
We report a case of acute myelogenous leukemia (AML) developed in a human immunodeficiency virus-infected patient, which is a very rare event. The subtype of AML was initially determined as...
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Hematopoietic Stem Cell Transplantation in Pediatric Acute Myelogenous Leukemia: Relevance of the Stem Cell Source to the Transplant Outcome

Yi HR, Han DK, Baek HJ, Kim YO, Kim SJ, Song ES, Kook H, Hwang TJ

BACKGROUND: Postremission therapy is critical for achieving long-term survival in the patients with acute myelogenous leukemia (AML). Allogeneic bone marrow transplantation during the first complete remission (CR) with using a...
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A Case of Granulocytic Sarcoma Relapsed in Both Breasts After Complete Remission of Acute Myelogeous Leukemia

Park SK, Suh SH, Nam HK, Kang AY, Kim DC, Han JY, Kim SH, Kwon HC, Kim JS, Kim HJ

  • KMID: 2038253
  • Korean J Lab Med.
  • 2005 Aug;25(4):223-226.
Granulocytic sarcoma (GS) is a localized tumor composed of immature granulocytic cells. GS can involve any site in the body. The common sites are periosteum, bone, soft tissue, lymph node,...
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Neutropenic Enterocolitis in Acute Myelogenous Leukemia

Oh SJ, Kim NK, Baik SH, Lee KY, Sohn SK, Maeng HY, Min YH

  • KMID: 2325057
  • J Korean Surg Soc.
  • 2005 Feb;68(2):149-152.
Neutropenic enterocolitis is an acute life-threatening, necrotizing inflammation of cecum and terminal ileum often seen in leukemia and lymphoma during periods of prolonged or severe neutropenia. It has been also...
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A Case of Trichosporon beigelii Fungemia Treated with Amphotericin B and Fluconazole in a Patient with Acute Myelogenous Leukemia

Jang MJ, Lee YK, Han KC, Hong SG, Kang MS, Oh D, Chong SY

  • KMID: 2252538
  • Korean J Hematol.
  • 2004 Jun;39(2):109-112.
Trichosporon beigelii is a causative agent of white piedra, an superficial hair shaft infection in immunocompetent individuals, and rarely of disseminated trichosporonosis in immunocompromised patients especially in neutropenic patients with...
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