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Mild Traumatic Brain Injury and Subsequent Acute Pulmonary Inflammatory Response

Lim SH, Jung H, Youn DH, Kim TY, Han SW, Kim BJ, Lee JJ, Jeon JP

Objective : The influence of moderate-to-severe traumatic brain injury (TBI) on acute pulmonary injury is well established, but the association between acute pulmonary injury and mild TBI has not been...
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Prevalence and outcomes of acute respiratory distress syndrome in patients with aneurysmal subarachnoid hemorrhage: a systematic review and meta-analysis

Fan TH, Huang M, Price C, Premraj L, Kannapadi NV, Suarez JI, Cho SM

Background: In this study, we aimed to investigate the prevalence, timing, risk factors, and outcomes of acute respiratory distress syndrome (ARDS) in patients with aneurysmal subarachnoid hemorrhage (aSAH). Methods: PubMed...
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Ventilator-induced lung-injury in mouse models: Is there a trap?

Joelsson JP, Ingthorsson S, Kricker J, Gudjonsson T, Karason S

Ventilator-induced lung injury (VILI) is a serious acute injury to the lung tissue that can develop during mechanical ventilation of patients. Due to the mechanical strain of ventilation, damage can...
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Possible roles of platelets in liver transplantation: regeneration and cancer recurrence

Han S

When tissue injury results to breakage, platelets are not only involved in plug formation and wound sealing, but they also play an important role throughout the tissue recovery process. Specifically,...
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Improved Differentiation Ability and Therapeutic Effect of miR-23a-3p Expressing Bone Marrow-Derived Mesenchymal Stem Cells in Mice Model with Acute Lung Injury

Zhang P, Liu L, Yao L, Song X

Background and Objectives: Implantation of bone marrow-derived mesenchymal stem cells (BMSCs) has been recognized as an effective therapy for attenuating acute lung injury (ALI). This study aims to discover microRNA...
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Predictive Role of Lung Injury Prediction Score in the Development of Acute Respiratory Distress Syndrome in Korea

Kim BK, Kim S, Kim CY, Kim YJ, Lee SH, Cha JH, Kim JH

Purpose: Early recognition and therapeutic intervention are important in patients at high risk of acute respiratory distress syndrome (ARDS). The lung injury prediction score (LIPS) has been used to predict...
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The Spectrum of CT Findings of COVID-19 Pneumonia:Acute Alveolar Insult and Organizing Pneumonia as Different Phases of Lung Injury and Repair

Kim YS, Kang UR, Kim YH

Purpose To analyze the findings and serial changes in chest CT lesions in 123 symptomatic patients with coronavirus disease 2019 (COVID-19). Materials and Methods From February 19 to April 7, 2020,...
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Liver-lung axes in alcohol-related liver disease

Arteel GE

Alcohol-related liver disease (ALD) and alcohol-related susceptibility to acute lung injury are the leading causes of morbidity and mortality due to chronic alcohol abuse. Most commonly, alcohol-induced injury to both...
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Veno-Veno Extracorporeal Membrane Oxygenation in Post-Traumatic Acute Lung Injury

Kim SH, Sul YH, Lee JY, Ye JB, Lee JS, Yoon SY, Kim JS

Patients with severe lung injury and hemorrhagic shock, may develop acute respiratory failure syndrome during resuscitation, and may require extracorporeal membrane oxygenation (ECMO) support to ensure adequate oxygenation to sustain...
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Convalescent Plasma Therapy in Coronavirus Disease 2019: a Case Report and Suggestions to Overcome Obstacles

Im JH, Nahm CH, Baek JH, Kwon HY, Lee JS

Coronavirus disease 2019 (COVID-19) is rapidly spreading around the world, causing much morbidity and mortality everywhere. However, effective treatments or vaccines are still not available. Although convalescent plasma (CP) therapy...
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Lung injury associated with inhalation of effective microorganism blends

Kim Jm, Kwak YJ, Yoon HI

Since 2009, effective microorganisms (EMs) have been supplied by the local government to the citizens of Seongnam, Korea, for various environment-protective uses including manufacturing detergents, cosmetics and humidifier disinfectants. A...
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Pulmonary Disease Related to E-Cigarettes

Park SY

The potential role of E-cigarettes in smoking cessation is debatable, and whether they are harmful remains controversial worldwide. However, several cases of E-cigarette or vaping-associated lung injury (EVALI) have been...
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Case Series of Transfusion-Related Acute Lung Injury in a Tertiary Hospital and a Practical Comparison with the New Diagnostic Criteria

Lee KS, Kim S, Roh J, Choi SJ, Kim HO

BACKGROUND: Transfusion-related acute lung injury (TRALI) is defined as acute respiratory distress syndrome with non-cardiogenic pulmonary edema caused by transfusion. It occurs only rarely but could result in patient mortality....
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The effects of BMS-470539 on lipopolysaccharide-induced acute lung injury

Jang EA, Kim JY, Tin TD, Song JA, Lee SH, Kwak SH

BACKGROUND: Overactivation of inflammatory cells, including macrophages and neutrophils, is associated with acute lung injury. BMS-470539 is a selective agonist of melanocortin 1 receptor, which triggers the inhibition of proinflammatory...
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Transfusion-related acute lung injury in a parturient diagnosed with myelodysplastic syndrome: A case report

Sung TY, Jee YS, Lee SJ, You HJ, Jeong KS, Kang PS

Transfusion-related acute lung injury (TRALI) is defined as a new episode of acute lung injury that occurs during or within 6 hours of a completed transfusion, which is one of...
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Clinical application of the Pediatric Acute Lung Injury Consensus Conference definition of acute respiratory distress syndrome

Kim BR, Kim SY, Sol IS, Kim YH, Kim KW, Sohn MH, Kim KE

PURPOSE: Despite improved quality of intensive care, acute respiratory distress syndrome (ARDS) significantly contributes to mortality in critically ill children. As pre-existing definitions of ARDS were adult-oriented standards, the Pediatric...
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Anti-inflammatory Role of Mesenchymal Stem Cells in an Acute Lung Injury Mouse Model

Huh JW, Kim WY, Park YY, Lim CM, Koh Y, Kim MJ, Hong SB

BACKGROUND: Mesenchymal stem cells (MSCs) attenuate injury in various lung injury models through paracrine effects. We hypothesized that intratracheal transplantation of allogenic MSCs could attenuate lipopolysaccharide (LPS)-induced acute lung injury...
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Histopathologic heterogeneity of acute respiratory distress syndrome revealed by surgical lung biopsy and its clinical implications

Park J, Lee YJ, Lee J, Park SS, Cho YJ, Lee SM, Kim YW, Han SK, Yoo CG

BACKGROUND/AIMS: Diffuse alveolar damage (DAD) is the histopathologic hallmark of acute respiratory distress syndrome (ARDS). However, there are several non-DAD conditions mimicking ARDS. The purpose of this study was to...
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Diosmetin Alleviates Lipopolysaccharide-Induced Acute Lung Injury through Activating the Nrf2 Pathway and Inhibiting the NLRP3 Inflammasome

Liu Q, Ci X, Wen Z, Peng L

Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) is a common clinical syndrome of diffuse lung inflammation with high mortality rates and limited therapeutic methods. Diosmetin, an active component from...
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Snorkeling-Induced Pulmonary Hemorrhage: A Case Report

Choo DM, Kim SS, Chung CU, Park DI, Kim JH

Swimming induced pulmonary alveolar hemorrhage is a rare disease. Here, we report a case of alveolar hemorrhage after snorkeling.
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