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Follicular Occlusion Triad: A Case Report

Yoon CM, Kwak JH, Han SH, Choi JA

Follicular occlusion triad (FOT) is a complex chronic inflammatory skin disease comprising hidradenitis suppurativa (HS), acne conglobata (AC), and dissecting cellulitis of the scalp (DCS; Hoffman’s disease or perifolliculitis capitis...
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Effect of Red Ginseng Oil on Cultured Sebocytes and Outer Root Sheath Cells after Treatment with Lipopolysaccharide

Jung HJ, Lee SH, Kwack MH, Lee WJ

Background: Ginseng has been known in Korea as a healthsupportive herbal medicine from time immemorial. Essential oil isolated from fresh ginseng has been shown to display antibacterial and anti-inflammatory activities....
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A Prospective Study about Application of Adapalene-benzoyl Peroxide-MLE Fixed Dose Combination Gel for the Treatment of Disease in Patients with Acne Vulgaris

Park SH, Park IH, Hwang SH, Jung SY, Wang HY, Kim H, Kim JU, Seol JE

  • KMID: 2504343
  • Korean J Dermatol.
  • 2020 Jul;58(6):382-388.
Background: Acne vulgaris is a chronic inflammatory disease of the pilosebaceous unit. Adapalene-benzoyl peroxide gel has been proven to be effective in the treatment of both inflammatory and comedonal acne....
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A Correlation between Serum Level of Alkaline Phosphatase and Acne Severity in Children and Adolescents: A Retrospective Cross-Sectional Study

Jue MS, Park E, Kang HS, Kim JS

Background: Acne is a chronic inflammatory disease of the pilosebaceous unit and usually affects adolescents when the peak concentrations of growth hormone, insulin-like growth factor 1, and androgen are demonstrated....
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Usage and Awareness of “Color Cosmetics” and Acne-targeting Cosmetics in Korean Middle School Students

Lee SH, Hong ES, Lee JD, Cho SH, Woo YR, Kim HS

  • KMID: 2502802
  • Korean J Dermatol.
  • 2020 Mar;58(3):174-178.
Background: The use of makeup is popular among Korean adolescents. With the increased use of color cosmetics, there are concerns that heavy application may cause skin problems or aggravate acne,...
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Minocycline and Its Impact on Microbial Dysbiosis in the Skin and Gastrointestinal Tract of Acne Patients

Thompson K, Rainer BM, Antonescu , Florea L, Mongodin E, Kang S, Chien AL

BACKGROUND: Associations between acne and gastrointestinal comorbidities suggest that microbial dysbiosis and intestinal permeability may promote inflammatory acne, a condition often managed with oral antibiotics. OBJECTIVE: We performed a case-control study...
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A Pilot Comparative Study of Alternating Blue and Red Light LED Phototherapy and Pulsed-dye Laser Therapy for Acne Vulgaris Treatment

Jeon JW, Bae JY, Jung HJ, Ahn J, Park MY

  • KMID: 2509671
  • Korean J Dermatol.
  • 2020 Dec;58(10):681-687.
Background: Light-based and laser therapy have emerged as alternative therapies for the treatment of acne. Blue and red light-emitting diode (LED) phototherapy and pulsed dye laser (PDL) therapy are recognized...
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Antimicrobial activity of Garcinia mangostana L. ethanol extract against Cutibacterium acnes and Staphylococcus aureus

Lim YK, Yoo SY, Park SN, Lee DS, Kook JK

The purpose of this study was to investigate the antimicrobial activity of the ethanol extract of Garcinia mangostana L. (mangosteen) against Cutibacterium acnes (6 strains) and Staphylococcus aureus (6 strains)....
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A Clinical Study on the Association between Sensitive Skin and Acne in Patients with Acne

Choi W, Myung KB, Hahn HJ, Cheong SH

  • KMID: 2457685
  • Korean J Dermatol.
  • 2019 Aug;57(7):355-362.
BACKGROUND: Acne is a common inflammatory skin disease that involves the seborrheic area, developing not only in adolescence but also in adulthood. Abnormal epidermal barrier function in acne is reported...
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The Difference in Sebum Secretion Affecting Development of Acne

Jung IS, Yun SJ, Lee JB

BACKGROUND: Although sebum secretion is crucial for acne development, acne lesion distribution is not always similar to the topographic differences of sebum secretion. OBJECTIVE: To analyze whether sebum secretion affects acne...
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Anxiety Sensitivity and Quality of Life in Patients with Acne

Acer E, Altınoz A, Erdogan HK, Agaoglu E, Yuksel Canakcı N, Saracoglu

BACKGROUND: Anxiety sensitivity (AS) is a continuous fundamental fear and defined as extreme fear of anxiety sensations and symptoms. High AS can cause tendency to anxiety disorders. There are many...
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Investigation on Acne Patients' Use and Awareness of Cosmetics for Acne

Lee JI, Jung HJ, Ahn JY, Park MY

  • KMID: 2454370
  • Korean J Dermatol.
  • 2019 Jul;57(6):307-313.
BACKGROUND: Some cosmetics used for treating acne are considered as cosmeceuticals. Consequently, patients with acne are now more likely to perceive such products as actual treatments. OBJECTIVE: We aimed to investigate...
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Inhibition of Insulin-Like Growth Factor-1–Induced Sebum Production by Bilobetin in Cultured Human Sebocytes

Wang C, Hwang YL, Li XM, Kim SJ, Zhu MJ, Lee JH, Jiang RH, Kim CD

BACKGROUND: Sebocytes are the major cells of sebaceous gland. The essential role of sebocytes is the production of sebum, a specific lipid mixture, that covers the body surface and provides...
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Successfully Treated Severe Acne Using Selective Electrothermolysis in a Patient with Nephrotic Syndrome

Ryu HJ, Park JH, Ryu SI, Kim BY, Chun SH

Acne is very common in adolescents and young adults. Although there are various conventional treatment modalities, some patients are prone to side effects and need alternative options. A 22-year-old male...
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Efficacy of Bacteriophages in Propionibacterium acnes-Induced Inflammation in Mice

Kim MJ, Eun DH, Kim SM, Kim J, Lee WJ

BACKGROUND: Bacteriophages have been introduced as living drugs for infectious diseases; thus, they may provide an alternative to conventional acne therapeutics in patients with non-responsive acne. OBJECTIVE: We investigated the effect...
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Comparison of the Efficacy of Azithromycin Versus Doxycycline in Acne Vulgaris: A Meta-Analysis of Randomized Controlled Trials

Kim JE, Park AY, Lee SY, Park YL, Whang KU, Kim HJ

BACKGROUND: Acne vulgaris is one of the most common disorders of the pilosebaceous unit. Although doxycycline is considered to be a first-line anti-acne antibiotic, various other antibiotics have been tried...
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Acne Severity Scoring Using Deep Learning

Lee SJ, Jeon JS, Ryu JY, Song HJ, Jo YJ, Bang CH, Park YM, Lee JH

  • KMID: 2436844
  • Korean J Dermatol.
  • 2018 Aug;56(7):421-425.
BACKGROUND: Acne is a chronic inflammatory disease of the pilosebaceous unit, mainly on the face. It can have various clinical manifestations and should be appropriately treated based on the severity....
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Adipose Stem Cells with Conditioned Media for Treatment of Acne Vulgaris Scar

Shan X, Choi JH, Kim KJ, Lee YJ, Ryu YH, Lee SJ, Moon SH, Rhie JW

This study was to investigate the effect of subcutaneous injection of the adipose stem cells (ASCs) with conditioned media (CM) in the treatment of acne vulgaris scar. We used Adult...
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Epidermal Growth Factor Attenuated the Expression of Inflammatory Cytokines in Human Epidermal Keratinocyte Exposed to Propionibacterium acnes

Kim JM, Choo JE, Lee HJ, Kim KN, Chang SE

BACKGROUND: While the beneficial effects of topical epidermal growth factor (EGF) on wound healing have been repeatedly reported, there are few reports about the effects of EGF on inflammatory skin...
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Study on the Usage of Acne Patches in Patients with Acne

Jung HJ, Jang DH, Lee JI, Bae JY, Ahn JY, Park MY

  • KMID: 2436994
  • Korean J Dermatol.
  • 2018 Nov;56(9):539-542.
BACKGROUND: Patients with acne are at risk of using various over-the-counter drugs (OTCs). In addition, several OTCs are introduced in pharmacies in Korea. However, only few drugs are supported by...
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