- A Novel Immunomodulatory Mechanism Dependent on Acetylcholine Secreted by Human Bone Marrow-derived Mesenchymal Stem Cells
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Yi TG, Cho YK, Lee HJ, Kim J, Jeon MS, Ham DS, Kim WC, Song SU
- KMID: 2465901
- Int J Stem Cells.
- 2019 Jul;12(2):315-330.
- doi: 10.15283/ijsc18098
BACKGROUND AND OBJECTIVES: Mesenchymal stem cells (MSCs) are used to treat autoimmune or inflammatory diseases. Our aim was to determine the immunomodulatory mechanisms elicited by MSCs during inflammation. METHODS AND RESULTS:... -
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- Association between Ischemic Electrocardiographic Changes during Acetylcholine Provocation Test and Long-Term Clinical Outcomes in Patients with Vasospastic Angina
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Im SI, Rha SW, Choi BG, Na JO, Choi CU, Lim HE, Kim JW, Kim EJ, Park CG, Seo HS
- KMID: 2451770
- Kosin Med J.
- 2019 Jun;34(1):1-14.
- doi: 10.7180/kmj.2019.34.1.1
OBJECTIVES: Intracoronary injection of acetylcholine (Ach) has been shown to induce significant coronary artery spasm (CAS) in patients with vasospastic angina. Clinical significance and angiographic characteristics of patients with ischemic... -
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- Activation of acetylcholine receptor elicits intracellular Ca2+ mobilization, transient cytotoxicity, and induction of RANKL expression
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Heo SJ, Kim MS
- KMID: 2354199
- Int J Oral Biol.
- 2016 Sep;41(3):119-123.
- doi: 10.11620/IJOB.2016.41.3.119
Acetylcholine receptors (AChR) including muscarinic and nicotinic AChR are widely expressed and mediate a variety of physiological cellular responses in neuronal and non-neuronal cells. Notably, a functional cholinergic system exists... -
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- Differential Effects of Quercetin and Quercetin Glycosides on Human α7 Nicotinic Acetylcholine Receptor-Mediated Ion Currents
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Lee BH, Choi SH, Kim HJ, Jung SW, Hwang SH, Pyo MK, Rhim H, Kim HC, Kim HK, Lee SM, Nah SY
- KMID: 2351690
- Biomol Ther.
- 2016 Jul;24(4):410-417.
- doi: 10.4062/biomolther.2015.153
Quercetin is a flavonoid usually found in fruits and vegetables. Aside from its antioxidative effects, quercetin, like other flavonoids, has a various neuropharmacological actions. Quercetin-3-O-rhamnoside (Rham1), quercetin-3-O-rutinoside (Rutin), and quercetin-3-(2(G)-rhamnosylrutinoside... -
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- Inducibility of human atrial fibrillation in an in silico model reflecting local acetylcholine distribution and concentration
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Hwang M, Lee HS, Pak HN, Shim EB
- KMID: 2150480
- Korean J Physiol Pharmacol.
- 2016 Jan;20(1):111-117.
- doi: 10.4196/kjpp.2016.20.1.111
Vagal nerve activity has been known to play a crucial role in the induction and maintenance of atrial fibrillation (AF). However, it is unclear how the distribution and concentration of... -
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- Changes in Acetylcholine Receptors and Functional Characterization in Muscle by TOF Stimulation in Rat Experimental Autoimmune Myasthenia Gravis (EAMG) Model
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Chon JY, Lee HJ
- KMID: 1937596
- Korean J Anesthesiol.
- 2007 Mar;52(3):310-317.
- doi: 10.4097/kjae.2007.52.3.310
BACKGROUND: The aim of study is to investigate the initial functional changes of muscle in rats induced to have myasthenia gravis, experimental autoimmune myasthenia gravis (EAMG). The authors investigated the... -
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- Comparison of the Long-Term Prognosis between Coronary Vasospasm and Intermediate Vasoconstriction Induced by the Administration of Acetylcholine
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Shin DI, Seung KB, Kim DB, Her SH, Ham JH, Seo SM, Shin WS, Kim PJ, Chang K, Baek SH, Chung WS, Kim JH, Hong SJ, Choi KB
- KMID: 2227098
- Korean Circ J.
- 2006 Jul;36(7):503-509.
- doi: 10.4070/kcj.2006.36.7.503
BACKGROUND AND OBJECTIVES: The degree of coronary vasoconstriction induced by acetylcholine administeration can vary. We compared the prognosis between coronary vasospasm and intermediate vasoconstriction, which were both induced by acetylcholine... -
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- Acetylcholine Receptor Antibody and Clinical Features in Childhood Onset Myasthenia Gravis
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Lee KH, Kim SJ, Lee JH, Lee M, Kim HS, Kim JK
- KMID: 2329321
- J Korean Child Neurol Soc.
- 2005 Nov;13(2):210-219.
PURPOSE: We studied 32 children with myasthenia gravis to evaluate clinical features and outcomes. Also, we tried to compare between seropositive and seronegative juvenile myasthenia gravis, and validate the clinical... -
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- Acetylcholine Induces Hyperpolarization Mediated by Activation of K (Ca) Channels in Cultured Chick Myoblasts
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Lee D, Han J, Park JY
- KMID: 2285308
- Korean J Physiol Pharmacol.
- 2005 Feb;9(1):37-43.
Our previous report demonstrated that chick myoblasts are equipped with Ca2+-permeable stretch- activated channels and Ca2+-activated potassium channels (KCa), and that hyperpolarization-induced by KCa channels provides driving force for Ca2+... -
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- The Effect of Acetylcholine on the Potassium Currents and Length of Outer Hair Cell
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Cho HH, Lee JK, Lee JH, Jang MJ, Huang M, Jeong HS, Cho YB, Park JS
- KMID: 2037111
- Korean J Otolaryngol-Head Neck Surg.
- 2005 Feb;48(2):153-157.
BACKGROUND AND OBJECTIVES: Inner hair cells (IHCs) of the organ of Corti change the external sound stimulus into the electrical signal and transmit this signal to the auditory cortex through... -
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- Effects of NMDA, AMPA and Kainate on the Release of Acetylcholine in Rat Hippocampal and Striatal Slices
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Kim DK, Lee S, Jung KY, Kim JK, Choi BK
- KMID: 1611486
- Korean J Physiol Pharmacol.
- 2004 Dec;8(6):301-305.
This study examined the effects of N-methyl-D-aspartate (NMDA), alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) and kainate on basal and electrically-evoked release of acetylcholine (ACh) from the rat hippocampal and striatal slices which... -
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- Effects of Pine Needle Butanol Fraction on Acetylcholine (ACh) and Its Related Enzymes in Brain of Rats
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Choi JH, Kim DI, Park SH, Kim NJ, Baek SJ, Kim KJ, Kim HS
- KMID: 2269777
- Korean J Nutr.
- 2004 Apr;37(3):176-181.
This study was designed to investigate the effects of buthanol (BuOH) fraction of pine (Pinus densiflora Sieb et Zucc) needle on cholesterol and lipofuscin (LF) accumulations, acetylcholine (ACh) and its... -
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- The Role of 5-HT Receptors on the Acetylcholine Release from the Rat Striatum
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Joo YH, Jung KY, Choi BK
- KMID: 1607282
- Korean J Psychopharmacol.
- 2001 Jun;12(2):140-146.
The aim of this study was to investigate the role of the 5-HT receptors in acetylcholine (ACh) release from the striatum. Slices from the rat striatum and synaptosomes were incubated... -
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- Mechanism of L-NAME-resistant endothelium-dependent relaxation induced by acetylcholine in rabbit renal artery
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Yeon DS, Ahn DS, Lee YH, Kwon SC
- KMID: 1581025
- Korean J Physiol Pharmacol.
- 2000 Dec;4(6):471-477.
In the rabbit renal artery, acetylcholine (ACh, 1 nM ~ 10 micrometer) induced endothelium-dependent relaxation of arterial rings precontracted with norepinephrine (NE, 1 micrometer) in a dose-dependent manner. NG-nitro-L-arginine (L-NAME, 0.1 mM), an... -
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- Effects of Acetylcholine on the Renal Function in Renal Hypertensive Rabbits
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Noh SM, Kim SH, Cho KW
- KMID: 1989885
- Korean J Nephrol.
- 2000 Nov;19(6):1012-1023.
It has long been known that acetylcholine infusion resulted in increases in urine volume, urinary excretion of Na and renal plasma flow. Exact mechanism of renal effects of acetylcholine, however,... -
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- The Effects of Temperature Changes on the Acetylcholine and Neostigmine Induced Contraction of Rabbit Trcheal Smooth Muscle
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Kwon OK, Kim CS, Ryu KH
- KMID: 2239038
- Korean J Anesthesiol.
- 1999 Nov;37(5):913-917.
- doi: 10.4097/kjae.1999.37.5.913
BACKGROUND: The body temperature of a patient changes changes during general anesthesia and cholinesterase inhibitor is usually administered at the end of general anesthesia to reverse the neuromuscular blocker effect.... -
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- Effect of Tetrahydro-9-Aminoacridine on Acetylcholine Release in the Rat Hippocampus
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Joo YH, Kim SW, Rho SH, Choi BK
- KMID: 1554204
- Korean J Psychopharmacol.
- 1999 Oct;10(2):173-179.
It is well known that the cholinergic innervation of hippocampal formation plays an important role in the process of memory and learning, and the deficit of this system might be... -
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- Calcium Sources Mediating Human Gallbladder Contraction by Acetylcholine end Cholecystokinin
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Yoon YB, Rhee JC, Rhee PL, Lee JK, Kang TM, Uhm DY
- KMID: 2084833
- Korean J Gastroenterol.
- 1998 Jun;31(6):799-813.
BACKGROUND AND AIMS: Gallbladder contraction regulates the bile flow during digestive period and pevents stasis of the lithogenic bile. In addition, abnormal gallbladder motility may cause recurtent biliary pain or... -
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- Contractile Response of the Rat Vas Deferens to Electrical Field Stimulation, Phenylephrine and Acetylcholine under Hypoxia
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Suh HJ, Lee DH, Yoon JY, Park YH
- KMID: 2290248
- Korean J Urol.
- 1998 Apr;39(4):316-322.
PURPOSE: The proper functioning of all smooth muscle structures depends on the ability of normal blood to deliver oxygen and nutrients to the muscles. In addition, hypoxia has been... -
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- Depolarizing Mechanisms of Acetylcholine in Gastric Smooth Muscle
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Jun JY, Yeum CH, Moon SH, Oh HK, Park YW, Lee SJ, Yun PJ
- KMID: 2240620
- Korean J Gastroenterol.
- 1998 Apr;31(4):421-431.
BACKGROUND AND AIMS: Acetylcholine which is a major excitatory neurotransmitter, depolarizes gastric smooth muscle cells. The aim of this study was to investigate the ionic mechanisms of acetylcholine-induced depolarization in... -
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