- A Case of Male Infertility with a Reciprocal Translocation t(X;14)(p11.4;p12)
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Hwang SH, Lee SM, Seo EJ, Choi KU, Park HJ, Park NC, Choi J, Lee EY
- KMID: 1781474
- Korean J Lab Med.
- 2007 Apr;27(2):139-142.
- doi: 10.3343/kjlm.2007.27.2.139
A chromosomal abnormality was found in about 3.6-7.6% of males presenting with azoospermia or oligospermia. Translocations between X chromosome and autosomes are rarely seen genetic disorders that cause male infertility.... -
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- Simultaneous Translocation of Both TCR Loci (14q11) with Rare Partner Loci (Xq22 and 12p13) in a Case of T-lymphoblastic Leukemia
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Kang DH, Kim SH, Jun JW, Lee YW, Shin HB, Ahn JY, Hong DS, Lee YK, Jeon BR
- KMID: 1381689
- Ann Lab Med.
- 2012 May;32(3):220-224.
- doi: 10.3343/alm.2012.32.3.220
The most common recurrent cytogenetic abnormalities in T-lymphoblastic leukemia (T-acute lymphoblastic leukemia [T-ALL]) involve T-cell receptor (TCR) loci and a variety of partner genes, including HOX11, HOX11L2, MYC, and TAL1.... -
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- A Novel Translocation t(1;5)(p32;q31) that Was Not Associated with the TAL1 Rearrangement in a Case of T Lymphoblastic Leukemia/Lymphoma
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Cho HS, Kim MK, Bae YK
- KMID: 1096970
- Korean J Lab Med.
- 2009 Jun;29(3):199-203.
- doi: 10.3343/kjlm.2009.29.3.199
Chromosome 1 band p32 (1p32) aberrations are common in T lymphoblastic leukemia/lymphoma (T-ALL/LBL). Two types of 1p32 aberrations include translocations with different partners and submicroscopic interstitial deletion. Both aberrations are... -
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- Three-way Translocation of MLL/MLLT3, t(1;9;11)(p34.2;p22;q23), in a Pediatric Case of Acute Myeloid Leukemia
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Jun KR, Lee JN, Park JA, Kim HR, Shin JH, Oh SH, Lee JY, Song SA
- KMID: 1094354
- Korean J Lab Med.
- 2011 Apr;31(2):127-129.
- doi: 10.3343/kjlm.2011.31.2.127
The chromosome band 11q23 is a common target region of chromosomal translocation in different types of leukemia, including infantile leukemia and therapy-related leukemia. The target gene at 11q23, MLL, is... -
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- B-cell Acute Lymphoblastic Leukemia With t(9;22)(q34;q11) Translocation and Clonal Divergence Through ider(22) Chromosome and t(13;17)(q14;q25) Translocation
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Meza-Espinoza JP, Romo Martinez EJ, Aguilar Lopez L, Picos Cardenas VJ, Magana Torres MT, Gonzalez Garcia JR
- KMID: 2373523
- Ann Lab Med.
- 2016 Mar;36(2):185-187.
- doi: 10.3343/alm.2016.36.2.185
No abstract available. -
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- A Rare Case of Acute Lymphoblastic Leukemia with t(12;17)(p13;q21)
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Kim JE, Woo KS, Kim KE, Kim SH, Park JI, Shaffer LG, Han JY
- KMID: 1781621
- Korean J Lab Med.
- 2010 Jun;30(3):239-243.
- doi: 10.3343/kjlm.2010.30.3.239
Patients with ALL rarely present with t(12;17)(p13;q21) as the primary clonal abnormality; this abnormality is associated with the expression of myeloid antigens. In this study, we have reported presumably the... -
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- A Case of Partial Trisomy 9pter --> q13 due to Paternal Balanced Translocation t (9;21) (q13;q21)
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Woo KS, Kim KE, Kwon EY, Kim JP, Han JY
- KMID: 854855
- Korean J Lab Med.
- 2008 Apr;28(2):155-159.
- doi: 10.3343/kjlm.2008.28.2.155
Trisomy 9p is one of the most frequent autosomal anomalies compatible with a long survival rate. Clinical characteristics are craniofacial dysmorphisms including hypertelorism, prominent nose, deepset eyes, and down-slanting palpebral... -
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- Prognostic Significance of TEL/AML1 Rearrangement and Its Additional Genetic Changes in Korean Childhood Precursor B-Acute Lymphoblastic Leukemia
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Chung HY, Kim KH, Jun KR, Jang S, Park CJ, Chi HS, Im HJ, Seo JJ, Seo EJ
- KMID: 1096811
- Korean J Lab Med.
- 2010 Feb;30(1):1-8.
- doi: 10.3343/kjlm.2010.30.1.1
BACKGROUND: TEL (ETV6)/AML1 (RUNX1) rearrangement is observed in approximately 20-25% of childhood precursor B-ALL and is associated with a favorable outcome. Additional genetic changes, associated with TEL/AML1, are frequently found.... -
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- A Rare Case of Microgranular Acute Promyelocytic Leukemia Associated with ider(17)(q10)t(15;17) in an Old-age Patient
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Kim MJ, Cho SY, Lim G, Yoon HS, Lee HJ, Suh JT, Lee J, Lee WI, Cho KS, Park TS
- KMID: 1094345
- Korean J Lab Med.
- 2011 Apr;31(2):86-90.
- doi: 10.3343/kjlm.2011.31.2.86
We present a rare case of microgranular variant acute promyelocytic leukemia (APL) associated with ider(17)(q10)t(15;17)(q22;q12) of an old-age patient. The initial chromosome study showed a 46,XX,del(6)(?q21q25),der(15)t(15;17)(q22;q12),ider(17)(q10)t(15;17)[10]/47,sl,+ider(17)(q10)t(15;17)[3]/46,XX[16]. FISH signals from a... -
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- t(12;17)(p13;q12)/TAF15-ZNF384 Rearrangement in Acute Lymphoblastic Leukemia
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Kim J, Kim HS, Shin S, Lee ST, Choi JR
- KMID: 2373567
- Ann Lab Med.
- 2016 Jul;36(4):396-398.
- doi: 10.3343/alm.2016.36.4.396
No abstract available. -
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- Four Cases of Chronic Myelogenous Leukemia in Mixed Phenotype Blast Phase at Initial Presentation Mimicking Mixed Phenotype Acute Leukemia with t(9;22)
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Choi W, Kim M, Lim J, Han K, Lee S, Lee JW, Chung NG, Kim Y
- KMID: 1781362
- Ann Lab Med.
- 2014 Jan;34(1):60-63.
- doi: 10.3343/alm.2014.34.1.60
No abstract available. -
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- A Novel KIT INDEL Mutation in Acute Myeloid Leukemia With t(8;21)(q22;q22); RUNX1-RUNX1T1
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Lee JH, Park C, Kim SH, Shin MG
- KMID: 2373559
- Ann Lab Med.
- 2016 Jul;36(4):371-374.
- doi: 10.3343/alm.2016.36.4.371
No abstract available. -
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- Prognostic Effect of cytoplasmic CD79a Expression in Acute Myeloid Leukemia with t(8;21)
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Chung HJ, Chi HS, Cho YU, Lee EH, Jang S, Park CJ, Seo EJ
- KMID: 1781541
- Korean J Lab Med.
- 2007 Dec;27(6):388-393.
- doi: 10.3343/kjlm.2007.27.6.388
BACKGROUND: Although cytoplasmic CD79a (cytCD79a) is a highly lineage-specific marker of B lymphoid cells and plays an important role in the diagnosis of acute leukemia, its clinical significance is... -
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- Detection of PML/RARA Rearrangement by Reverse Transcriptase-PCR and Sequencing in a Case of Microgranular Acute Promyelocytic Leukemia Lacking t(15;17) on Karyotype and FISH
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Kim KE, Woo KS, Kim SH, Han JY
- KMID: 1077411
- Korean J Lab Med.
- 2009 Oct;29(5):379-383.
- doi: 10.3343/kjlm.2009.29.5.379
We report a case of morphologically microgranular acute promyelocytic leukemia with PML/RARA fusion transcripts demonstrated by reverse transcriptase-PCR and cDNA sequencing, and no PML/RARA fusion detected by karyotype and FISH... -
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- A Case of t(3;3)(q21;q26.2) Associated with Severe Multilineage Dysplasia and Multi-drug Resistance in Blastic Crisis of Chronic Myelogenous Leukemia
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Lee SA, Lim J, Kim M, Kim Y, Han K
- KMID: 1781665
- Korean J Lab Med.
- 2010 Dec;30(6):595-599.
- doi: 10.3343/kjlm.2010.30.6.595
The t(3;3)(q21;q26.2) is known to be mainly observed in hematologic myeloid malignancies, as a form of 3q21q26 syndrome. Cytogenetic abnormalities of 3q21q26 syndrome result in RPN1-EVI1 fusion transcripts involving ecotropic... -
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- Detection of RUNX1-MECOM Fusion Gene and t(3;21) in a Very Elderly Patient Having Acute Myeloid Leukemia with Myelodysplasia-Related Changes
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Yang JJ, Cho SY, Suh JT, Lee HJ, Lee WI, Yoon HJ, Baek SK, Park TS
- KMID: 1387352
- Ann Lab Med.
- 2012 Sep;32(5):362-365.
- doi: 10.3343/alm.2012.32.5.362
An 87-yr-old woman was diagnosed with AML with myelodysplasia-related changes (AML-MRC). The initial complete blood count showed Hb level of 5.9 g/dL, platelet counts of 27x10(9)/L, and white blood cell... -
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- A Case of Adult B Lymphoblastic Leukemia with ider(9)(q10)t(9;22)(q34;q11.2) and der(19)t(1;19)(q23;p13.3)
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Jung SI, Cho HS, Lee CH, Jung BC
- KMID: 1781663
- Korean J Lab Med.
- 2010 Dec;30(6):585-590.
- doi: 10.3343/kjlm.2010.30.6.585
In B lymphoblastic leukemia/lymphoma (B-ALL/LBL), t(9;22)(q34;q11.2) and t(1;19)(q23;p13.3) are recurrent cytogenetic abnormalities. The concurrent occurrence of both abnormalities is very rare, and only 3 cases have been previously reported. Here,... -
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- A Case of Therapy-related Acute Lymphoblastic Leukemia with t(11;19)(q23;p13.3) and MLL/MLLT1 Gene Rearrangement
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Yoo BJ, Nam MH, Sung HJ, Lim CS, Lee CK, Cho YJ, Lee KN, Yoon SY
- KMID: 1096654
- Korean J Lab Med.
- 2011 Jan;31(1):13-17.
- doi: 10.3343/kjlm.2011.31.1.13
Therapy-related ALL (t-ALL) is a rare secondary leukemia that develops after chemotherapy and/or radiotherapy for primary malignancies. Chromosomal 11q23 abnormalities are the most common karyotypic alterations in t-ALL. The t(11;19)(q23;p13)... -
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- A Case of Central Nervous System Myelomatosis with Complex Chromosome Aberrations
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Bang HI, Yoo JY, Kim KH, Park R, Shin JW, Choi TY, Lee SC, Park HS, Won JH
- KMID: 1781637
- Korean J Lab Med.
- 2010 Aug;30(4):334-338.
- doi: 10.3343/kjlm.2010.30.4.334
Involvement of the central nervous system is very uncommon in multiple myeloma, observed in approximately 1% of the multiple myeloma patients. We report a case of central nervous system myelomatosis... -
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- A Case of Therapy-related ALL with MLL Gene Rearrangement Following Treatment of Breast Cancer
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Cho J, Hur M, Moon HW, Yun YM, Lee CH, Lee HG
- KMID: 1781624
- Korean J Lab Med.
- 2010 Jun;30(3):255-259.
- doi: 10.3343/kjlm.2010.30.3.255
ALL with MLL gene rearrangement secondary to chemotherapy has been rarely reported. We report a case of therapy-related ALL (t-ALL) with MLL gene rearrangement in a patient who had undergone... -
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