- MiR-494-3p Upregulation Exacerbates Cerebral Ischemia Injury by Targeting Bhlhe40
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Sun L, Ji D, Zhi F, Fang Y, Zhu Z, Ni T, Zhu Q, Bao J
- KMID: 2527521
- Yonsei Med J.
- 2022 Apr;63(4):389-398.
- doi: 10.3349/ymj.2022.63.4.389
Purpose: Cerebral ischemia is related to insufficient blood supply and is characterized by abnormal reactive oxygen species (ROS) production and cell apoptosis. Previous studies have revealed a key role for... -
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- Establishment and evaluation of a murine alphavbeta3-integrin-expressing cell line with increased susceptibility to Foot-and-mouth disease virus
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Zhang W, Lian K, Yang F, Yang Y, Zhu Z, Zhu Z, Cao W, Mao R, Jin Y, He J, Guo J, Liu X, Zheng H
- KMID: 2344298
- J Vet Sci.
- 2015 Sep;16(3):265-272.
- doi: 10.4142/jvs.2015.16.3.265
Integrin alphavbeta3 plays a major role in various signaling pathways, cell apoptosis, and tumor angiogenesis. To examine the functions and roles of alphavbeta3 integrin, a stable CHO-677 cell line expressing... -
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- Molecular phylogenetic studies on clinical bovine piroplasmosis caused by benign Theileria in Shaanxi Province, China
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Wang J, Zhang J, Zhu Z, Zhou X, Li B
- KMID: 2427034
- J Vet Sci.
- 2018 Nov;19(6):846-849.
- doi: 10.4142/jvs.2018.19.6.846
A group of benign Theileria species, which are often referred to as T. orientalis/T. buffeli/T. sergenti group, has low pathogenicity in cattle. Herein, we report on Theileria spp. in cattle... -
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- Transient Receptor Potential Vanilloid Type-1 Channel in Cardiometabolic Protection
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Wang P, Liu D, Zhu Z
- KMID: 2196452
- J Korean Soc Hypertens.
- 2011 Jun;17(2):37-47.
- doi: 10.5646/jksh.2011.17.2.37
Transient receptor potential vanilloid type-1 channel (TRPV1) is a non-selective cation channel with a preference for calcium ions that is able to sense a vast range of endogenous physical and... -
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- The Atopic March: Progression from Atopic Dermatitis to Allergic Rhinitis and Asthma
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Zheng T, Yu J, Oh MH, Zhu Z
- KMID: 2130356
- Allergy Asthma Immunol Res.
- 2011 Apr;3(2):67-73.
- doi: 10.4168/aair.2011.3.2.67
Atopic dermatitis (AD) is an inflammatory disease characterized by pruritic skin lesions. The pathogenesis of AD may include disrupted epidermal barrier function, immunodysregulation, and IgE-mediated sensitization to food and environmental... -
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- NUP210 and MicroRNA-22 Modulate Fasto Elicit HeLa Cell Cycle Arrest
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Gu Q, Hou W, Liu H, Shi L, Zhu Z, Ye W, Ni X
- KMID: 2500074
- Yonsei Med J.
- 2020 May;61(5):371-381.
- doi: 10.3349/ymj.2020.61.5.371
Purpose: Cervical cancer is one of the most fatal diseases among women in under-developed countries. To improve cervical cancer treatment, discovery of new targets is needed. In this study, we investigated... -
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- Non-invasive evaluation of testicular torsion using ultrasound shear wave elastography: an experimental study
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Lin Y, Lu W, Li G, Mao L, Ouyang L, Zhu Z, Chen S, Liang P, Jin H, Gao L, Liang J, Qiu S, Chen F
- KMID: 2552900
- Ultrasonography.
- 2024 Mar;43(2):98-109.
- doi: 10.14366/usg.23171
Purpose: The goal of this study was to examine changes in testicular stiffness at various intervals after the induction of testicular torsion, as well as to assess the predictive value... -
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- Excessive Startle with Novel GLRA1 Mutations in 4 Chinese Patients and a Literature Review of GLRA1-Related Hyperekplexia
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Zhan F, Zhang C, Wang S, Zhu Z, Chen G, Zhao M, Cao L
- KMID: 2506814
- J Clin Neurol.
- 2020 Apr;16(2):230-236.
- doi: 10.3988/jcn.2020.16.2.230
Background and Purpose Hyperekplexia (HPX), a rare neurogenetic disorder, is classically characterized by neonatal hypertonia, exaggerated startle response provoked by the sudden external stimuli and followed by a shortly general stiffness.... -
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- Atorvastatin regulates the migration and invasion of prostate cancer through the epithelial-mesenchymal transformation and matrix metalloproteinase pathways
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Zhu Z, Cao Y, Liu L, Zhao Z, Yin H, Wang H
- KMID: 2529362
- Investig Clin Urol.
- 2022 May;63(3):350-358.
- doi: 10.4111/icu.20210411
Purpose: Our purpose was to verify the effects of atorvastatin (ATO) on prostate cancer (PCa) proliferation, apoptosis, invasion, and metastasis and to further explore the drug’s mechanism of action. Materials and... -
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- Correlations of nasal responses to leukotriene D4 and histamine nasal provocation with quality of life in allergic rhinitis
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Zhu Z, Xie Y, Guan W, Gao Y, Xia S, Shi X, Zheng J
- KMID: 2397021
- Asia Pac Allergy.
- 2016 Oct;6(4):245-252.
- doi: 10.5415/apallergy.2016.6.4.245
BACKGROUND: The symptoms of allergic rhinitis (AR) greatly affect the quality of life (QoL) in the patients with AR. The correlations of nasal response to leukotriene D4 (LTD4) and histamine... -
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- Evaluation of Neck Lymph Node Metastasis on Contrast-Enhanced Ultrasound: An Animal Study
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Cui Z, Gao Y, Wang W, Zhu Z, Zhang Y, Ma Z
- KMID: 2376417
- Clin Exp Otorhinolaryngol.
- 2017 Mar;10(1):109-114.
- doi: 10.21053/ceo.2015.01284
OBJECTIVES: To assess the performance of contrast-enhanced ultrasound (CEUS) intended to differentiate hyperplastic from malignant neck lymph nodes in an animal model. METHODS: Twenty-four New Zealand rabbits were randomly divided into... -
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- Graded-Three-Dimensional Cell-Encapsulating Hydrogel as a Potential Biologic Scaffold for Disc Tissue Engineering
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Li Z, Zhang Y, Zhao Y, Gao X, Zhu Z, Mao Y, Qian T
- KMID: 2533930
- Tissue Eng Regen Med.
- 2022 Oct;19(5):1001-1012.
- doi: 10.1007/s13770-022-00480-2
BACKGROUND: Intervertebral disk (IVD) degeneration, which can cause lower back pain, is a major predisposing factor for disability and can be managed through multiple approaches. However, there is no satisfactory... -
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- Helmet CPAP versus Oxygen Therapy in Hypoxemic Acute Respiratory Failure: A Meta-Analysis of Randomized Controlled Trials
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Luo Y, Luo Y, Li Y, Zhou L, Zhu Z, Chen Y, Huang Y, Chen X
- KMID: 2374126
- Yonsei Med J.
- 2016 Jul;57(4):936-941.
- doi: 10.3349/ymj.2016.57.4.936
PURPOSE: The efficacy of helmet continuous positive airway pressure (CPAP) in hypoxemic acute respiratory failure (hARF) remains unclear. The aim of this meta-analysis was to critically review studies that investigated... -
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- Quantifying carotid stiffness in a pre-hypertensive population with ultrafast ultrasound imaging
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Ma X, Zhu Z, Wang Y, Shen B, Jiang X, Liu W, Wu Y, Zou C, Luan Y, Gao H, Huang H
- KMID: 2537424
- Ultrasonography.
- 2023 Jan;42(1):89-99.
- doi: 10.14366/usg.22039
Purpose: The aim of this study was to assess carotid stiffening in a pre-hypertensive (PHT) population using ultrafast pulse wave velocity (ufPWV). Methods: This study retrospectively enrolled 626 individuals who underwent... -
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- Carotid stiffening predicts cardiovascular risk stratification in mid-life: non-invasive quantification with ultrafast ultrasound imaging
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Zhu Z, Chen L, Liu W, Wu Y, Zou C, Zhang X, He S, Wang Y, Shen B, Ma X, Gao H, Luan Y, Huang H
- KMID: 2531434
- Ultrasonography.
- 2022 Jul;41(3):462-472.
- doi: 10.14366/usg.21197
Purpose: The present study investigated the association between Systematic COronary Risk Evaluation (SCORE)-estimated cardiovascular risk and carotid stiffening in a middle-aged population using ultrafast pulse wave velocity (ufPWV). Methods: This study... -
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- Melatonin Attenuates Mitochondrial Damage in Aristolochic AcidInduced Acute Kidney Injury
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Sun J, Pan J, Liu Q, Cheng J, Tang Q, Ji Y, Cheng K, wang R, Liu L, Wang D, Wu N, Zheng X, Li J, Zhang X, Zhu Z, Ding Y, Zheng F, Li J, Zhang Y, Yuan Y
- KMID: 2537586
- Biomol Ther.
- 2023 Jan;31(1):97-107.
- doi: 10.4062/biomolther.2022.054
Aristolochic acid (AA), extracted from Aristolochiaceae plants, plays an essential role in traditional herbal medicines and is used for different diseases. However, AA has been found to be nephrotoxic and... -
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- Protective effects of basic fibroblast growth factor in the development of emphysema induced by interferon-gamma
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Lee BJ, Moon HG, Shin TS, Jeon SG, Lee EY, Gho YS, Lee CG, Zhu Z, Elias JA, Kim YK
- KMID: 1104386
- Exp Mol Med.
- 2011 Apr;43(4):169-178.
- doi: 10.3858/emm.2011.43.4.018
Recent clinical evidence indicates that the non-eosinophilic subtype of severe asthma is characterized by fixed airway obstruction, which may be related to emphysema. Transgenic studies have demonstrated that high levels... -
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- IL-12-STAT4-IFN-gamma axis is a key downstream pathway in the development of IL-13-mediated asthma phenotypes in a Th2 type asthma model
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Kim YS, Choi SJ, Choi JP, Jeon SG, Oh SY, Lee BJ, Gho YS, Lee CG, Zhu Z, Elias JA, Kim YK
- KMID: 1104380
- Exp Mol Med.
- 2010 Aug;42(8):533-546.
- doi: 10.3858/emm.2010.42.8.054
IL-4 and IL-13 are closely related cytokines that are produced by Th2 cells. However, IL-4 and IL-13 have different effects on the development of asthma phenotypes. Here, we evaluated downstream... -
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