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Amyloid Precursor Protein Binding Protein-1 Is Up-regulated in Brains of Tg2576 Mice

Yang HJ, Joo Y, Hong BH, Ha SJ, Woo RS, Lee SH, Suh YH, Kim HS

Amyloid precursor protein binding protein-1 (APP-BP1) binds to the carboxyl terminus of amyloid precursor protein and serves as a bipartite activation enzyme for the ubiquitin-like protein, NEDD8. Previously, it has...
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The Efficacy of Shikonin on Cartilage Protection in a Mouse Model of Rheumatoid Arthritis

Kim YO, Hong SJ, Yim SV

The potential therapeutic action of shikonin in an experimental model of rheumatoid arthritis (RA) was investigated. As a RA animal model, DBA/1J mice were immunized two times with type II...
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Toll-like Receptor3-mediated Induction of Chemokines in Salivary Epithelial Cells

Li J, Jeong MY, Bae JH, Shin YH, Jin M, Hang SM, Lee JC, Lee SJ, Park K

Toll-like receptors (TLRs) functionally expressed in salivary epithelial cells, but their roles remain elusive. Among TLRs family, TLR3 is activated by dsRNA, a byproduct of viral infection. The aim of...
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Proteomic Analysis of Differentially Expressed Proteins in Bovine Endometrium with Endometritis

Choe C, Park JW, Kim ES, Lee SG, Park SY, Lee JS, Cho MJ, Kang KR, Han J, Kang D

Endometritis is one of the primary reasons for reproductive failure. In order to investigate endometritis-associated marker proteins, proteomic analysis was performed on bovine endometrium with endometritis. In bovine endometritis, desmin,...
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Changes in Endothelin Receptor Type B and Neuronal Nitric Oxide Synthase in Puromycin Aminonucleoside-Induced Nephrotic Syndrome

Bae EH, Kim SW

The collecting duct endothelin (ET) system, which involves ET-1 and its two receptors, may play a role in the regulation of renal sodium in association with the nitric oxide synthase...
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Chronic Administration of Monosodium Glutamate under Chronic Variable Stress Impaired Hypothalamic-Pituitary-Adrenal Axis Function in Rats

Seo HJ, Ham HD, Jin HY, Lee WH, Hwang HS, Park SA, Kim YS, Choi SC, Lee S, Oh KJ, Kim BS, Park BR, Lee MY

The hypothalamic-pituitary-adrenal (HPA) axis is the primary endocrine system to respond to stress. The HPA axis may be affected by increased level of corticotrophin-releasing factors under chronic stress and by...
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Inhibitory Effects of Olmesartan on Catecholamine Secretion from the Perfused Rat Adrenal Medulla

Lim HJ, Kim SY, Lim DY

The present sutdy aimed to determine whether olmesartan, an angiotensin II (Ang II) type 1 (AT1) receptor blocker, can influence the CA release from the isolated perfused model of the...
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