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Ca2+-dependent Long-term Inactivation of Cardiac Na+/Ca2+ Exchanger

Lee JE, Kang TM

  • KMID: 2285341
  • Korean J Physiol Pharmacol.
  • 2007 Oct;11(5):183-188.
Using BHK cells with stable expression of cardiac Na+/Ca2+ exchanger (BHK-NCX1), reverse mode (i.e. Ca2+ influx mode) of NCX1 current was recorded by whole-cell patch clamp. Repeated stimulation of reverse...
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Mechanical Hyperalgesia Induced by Blocking Calcium-activated Potassium Channels on Capsaicin-sensitive Afferent Fiber

Lee KH, Shin HK

  • KMID: 2285345
  • Korean J Physiol Pharmacol.
  • 2007 Oct;11(5):215-219.
Small and large conductance Ca2+-activated K+ (SKCa and BKCa) channels are implicated in the modulation of neuronal excitability. We investigated how changes in peripheral KCa channel activity affect mechanical sensitivity...
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Inhibition of the Desensitization of Canonical Transient Receptor Potential Channel 5 by Dimethyl Sulfoxide

Kim BJ, So I

  • KMID: 2285347
  • Korean J Physiol Pharmacol.
  • 2007 Oct;11(5):227-231.
The classic type of transient receptor potential channel (TRPC) is a molecular candidate for Ca2+-permeable cation channel in mammalian cells. TRPC5 is rapidly desensitized after activation by G protein-coupled receptor....
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Multiple 5-Hydroxytryptamine (5-HT) Receptors Are Involved in the Melittin-induced Nociceptive Responses in Rat I. Role of Peripheral 5-HT Receptor

Shin HK, Lee SE

  • KMID: 2285346
  • Korean J Physiol Pharmacol.
  • 2007 Oct;11(5):221-226.
Melittin-induced tonic pain model is characterized by local inflammation, edema, spontaneous flinchings, and sustained mechanical hypersensitivity. These nociceptive responses are mediated through selective activation of capsaicin-sensitive primary afferent fibers by...
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Neuroprotective Effects of Methanol Extracts of Jeju Native Plants on Hydrogen Peroxide-induced Cytotoxicity in SH-SY5Y Human Neuroblastoma Cells

Kong PJ, Kim YM, Lee HJ, Kim SS, Yoo ES, Chun W

  • KMID: 2285339
  • Korean J Physiol Pharmacol.
  • 2007 Oct;11(5):171-174.
Neuronal death is a common characteristic hallmark of a variety of neurodegenerative disorders including Alzheimer's disease and Parkinson's disease. However, there have been no effective drugs to successfully prevent neuronal...
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Regulation of Ba2+-Induced Contraction of Murine Ureteral Smooth Muscle

Kim YC, Lee MY, Kim WJ, Myung SC, Choi W, Kim CH, Xu WX, Kim SR, Lee SJ

  • KMID: 2285344
  • Korean J Physiol Pharmacol.
  • 2007 Oct;11(5):207-213.
This study was designed to characterize ureteral smooth muscle motility and also to study the effect of forskolin (FSK) and isoproterenol (ISO) on smooth muscle contractility in murine ureter. High...
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Effects of Antioxidants on the Gamma-Radiation Damage of the Cultured Vascular Smooth Mucle Cells of Rat Aorta

Lee JD, Choi HC, Kang YJ, Kim MS, Lee KY

  • KMID: 2285342
  • Korean J Physiol Pharmacol.
  • 2007 Oct;11(5):189-195.
To study the protective effects of antioxidants on the radiation damages of the cells, vascular smooth muscle cells (VSMC) from thoracic aorta of Sprague-Dawley rats were cultured and irradiated with...
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Protein Kinase C-mediated Neuroprotective Action of (-)-epigallocatechin-3-gallate against Abeta1-42-induced Apoptotic Cell Death in SH-SY5Y Neuroblastoma Cells

Jang S, You KW, Kim SH, Park SJ, Jeong HS, Park JS

  • KMID: 2285338
  • Korean J Physiol Pharmacol.
  • 2007 Oct;11(5):163-169.
The neurotoxicity of amyloid beta (Abeta) is associated with an increased production of reactive oxygen species and apoptosis, and it has been implicated in the development of Alzheimer's disease. While...
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Influence of SKF81297 on Catecholamine Release from the Perfused Rat Adrenal Medulla

Choi DH, Cha JH, Lim DY

  • KMID: 2285343
  • Korean J Physiol Pharmacol.
  • 2007 Oct;11(5):197-206.
The aim of the present study was to investigate the effects of 6-chloro-7,8-dihydroxy-1-phenyl-2,3, 4,5-tetrahydro-1H-3-benzazepine (SKF81297), a selective agonist of dopaminergic D1 receptor, on the secretion of catecholamines (CA) evoked by...
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Prostaglandin E1 Increases cGMP Levels in Beating Rabbit Atria: Lack of Effects of PGE1-induced Cyclic Nucleotides on Secretory and Contractile Functions

Jin XS, Quan HX, Kim SY, Park SH, Kim SZ, Lee HS, Cho KW

  • KMID: 2285340
  • Korean J Physiol Pharmacol.
  • 2007 Oct;11(5):175-182.
Members of prostaglandin (PG) E-series elicit cellular effects mainly through adenylyl cyclase-cAMP signaling. The role of PGE2-induced increase in cAMP has been shown to be compartmentalized in the cardiac myocytes:...
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