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Insulin Resistance of Skeletal Muscle was Recovered by Leptin Injection in vivo, but not in vitro, in High-fat Diet Fed Rats

Doh KO, Park JO, Jeon JR, Kim JY

  • KMID: 2285319
  • Korean J Physiol Pharmacol.
  • 2005 Apr;9(2):125-130.
We examined the effect of leptin on the insulin resistance in skeletal muscles by measuring the glucose transport. Male Wistar rats were fed with chow or high-fat diets for 30...
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Morphine-induced Modulation of Nociceptive Spinal Dorsal Horn Neuronal Activities after Formalin-induced Inflammatory Pain

Park JM, Li KW, Jung SJ, Kim J, Kim SJ

  • KMID: 2285313
  • Korean J Physiol Pharmacol.
  • 2005 Apr;9(2):77-86.
In this study, we examined the morphine-induced modulation of the nociceptive spinal dorsal horn neuronal activities before and after formalin-induced inflammatory pain. Intradermal injection of formalin induced time-dependent changes in...
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Enhanced Expression of Cell Adhesion Molecules in the Aorta of Diabetic Mice is Mediated by gp91phox-derived Superoxide

Yun MR, Kim JJ, Lee SM, Heo HJ, Bae SS, Kim CD

  • KMID: 2285317
  • Korean J Physiol Pharmacol.
  • 2005 Apr;9(2):109-115.
Endothelial activation and subsequent recruitment of inflammatory cells are important steps in atherogenesis. The increased levels of cell adhesion molecules (CAM) have been identified in diabetic vasculatures, but the underlying...
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Regulation of L-type Calcium Channel Current by Somatostatin in Guinea-Pig Gastric Myocytes

Kim YC, Sim JH, Lee SJ, Kang TM, Kim SJ, Kim SR, Youn SJ, Lee SJ, Xu WX, So I, Kim KW

  • KMID: 2285316
  • Korean J Physiol Pharmacol.
  • 2005 Apr;9(2):103-108.
To study the direct effect of somatostatin (SS) on calcium channel current (IBa) in guinea-pig gastric myocytes, IBa was recorded by using whole-cell patch clamp technique in single smooth muscle...
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Modulation of Large Conductance Ca2+-activated K+ Channel of Skin Fibroblast (CRL-1474) by Cyclic Nucleotides

Yun J, Kim S, Bang H

  • KMID: 2285320
  • Korean J Physiol Pharmacol.
  • 2005 Apr;9(2):131-135.
Potassium channels in human skin fibroblast have been studied as a possible site of Alzheimer disease pathogenesis. Fibroblasts in Alzheimer disease show alterations in signal transduction pathway such as changes...
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Higher Expression of TRPM7 Channels in Murine Mature B Lymphocytes than Immature Cells

Kim JK, Ko JH, Nam JH, Woo JE, Min KM, Earm YE, Kim SJ

  • KMID: 2285312
  • Korean J Physiol Pharmacol.
  • 2005 Apr;9(2):69-75.
TRPM7, a cation channel protein permeable to various metal ions such as Mg2+, is ubiquitously expressed in variety of cells including lymphocytes. The activity of TRPM7 is tightly regulated by...
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Inhibition of Angiotensin II-Induced Vascular Smooth Muscle Cell Hypertrophy by Different Catechins

Zheng Y, Song HJ, Yun SH, Chae YJ, Jia H, Kim CH, Ha TS, Sachinidis A, Ahn HY, Davidge ST

  • KMID: 2285318
  • Korean J Physiol Pharmacol.
  • 2005 Apr;9(2):117-123.
A cumulative evidence indicates that consumption of tea catechin, flavan-3-ol derived from green tea leaves, lowers the risk of cardiovascular diseases. However, a precise mechanism for this cardiovascular action has...
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Na+-Ca2+ Exchange Curtails Ca2+ before Its Diffusion to Global Ca2+i in the Rat Ventricular Myocyte

Ahn SW, Ko CM

  • KMID: 2285315
  • Korean J Physiol Pharmacol.
  • 2005 Apr;9(2):95-101.
In the heart, Na+-Ca2+ exchange (NCX) is the major Ca2+ extrusion mechanism. NCX has been considered as a relaxation mechanism, as it reduces global [Ca2+]i raised during activation. However, if...
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Ca2+-induced Ca2+ Release from Sarcoplasmic Reticulum Negatively Regulates Myocytic ANP Release in Beating Rabbit Atria

Li D, Quan HX, Wen JF, Jin JY, Park SH, Kim SY, Kim SZ, Cho KW

  • KMID: 2285314
  • Korean J Physiol Pharmacol.
  • 2005 Apr;9(2):87-94.
It is not clear whether Ca2+-induced Ca2+ release from the sarcoplasmic reticulum (SR) is involved in the regulation of atrial natriuretic peptide (ANP) release. Previously, we have shown that nifedipine...
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