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Current Issues in Migraine Genetics

Lee JY, Kim M

Migraine often runs in families and is associated with both genetic and environmental factors. Clinical and genetic heterogeneity as well as the influence of environmental factors have hampered the identification...
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Embolic Infarction Associated with Cardiac Amyloidosis

Cho KH, Cho YM, Kim JS

Embolic cerebral infarction due to cardiac amyloidosis is rare. We report two patients with amyloidosis who developed cerebral infarcts. These embolic infarcts were probably related to cardiac involvement of amyloidosis,...
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Aseptic Meningitis in Kikuchi's Disease

Yang HD, Lee SI, Son IH, Suk SH

The involvement of the nervous system in Kikuchi's disease (KD) is rare. Although some reports of meningeal involvement in KD were described in the literature from Japan, it has rarely...
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Wall-Eyed Monocular Internuclear Ophthalmoplegia (WEMINO) with Contraversive Ocular Tilt Reaction

Jeon SB, Chung SJ, Ahn H, Lee JH, Jung JM, Lee MC

Wall-eyed monocular internuclear ophthalmoplegia (WEMINO) with contraversive ocular tilt reaction has not been previously reported. A 71-year-old woman suddenly developed blurred vision. Examination revealed left internuclear ophthalmoplegia, left exotropia, right...
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A Case of Biopsy-proven Early-onset Alzheimer's Disease with Hemiparkinsonism

Choi EJ, Bang H, Im JH, Chung SJ, Lee JH

Patients with dementia and concomitant parkinsonism are frequently encountered in the elderly population. When it comes to young adults, however, coexistence of Alzheimer's disease (AD) and Parkinson's disease (PD) is...
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Association of Metabolic Syndrome and C-reactive Protein Levels with Intracranial Atherosclerotic Stroke

Bang OY, Lee MA, Lee JH, Kim JW, Lee PH, Joo IS, Huh K

BACKGROUND: The risk factors for intracranial atherosclerosis are unclear but may differ from those for other stroke subtypes. Here, we investigated whether metabolic syndrome, an emerging risk factor for cardiovascular...
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Relationship Between Essential Tremor and Cerebellar Dysfunction According to Age

Lim ES, Seo MW, Woo SR, Jeong SY, Jeong SK

BACKGROUND: The cerebellum and its neural circuitry have been assumed to play a major role in the pathophysiology of essential tremor (ET). In this study, we sought to find associations...
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Non-cardioembolic Mechanisms in Cryptogenic Stroke: Clinical and Diffusion-weighted Imaging Features

Bang OY, Lee PH, Yeo SH, Kim JW, Joo IS, Huh K

BACKGROUND: The role of several cardiogenic risk factors, including patent foramen ovale, in patients with cryptogenic stroke has been extensively studied. However, little attention has been paid to the role...
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Intracranial Atherosclerosis: Incidence, Diagnosis and Treatment

Kim JS, Kang DW, Kwon SU

Intracranial atherosclerosis is considered a cause of approximately 8% of all strokes in the western society. However, its frequency is much higher in Asian countries. In our hospital-based study, among...
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Factors Affecting the Quality of Life After Ischemic Stroke: Young Versus Old Patients

Kim JS, Choi-Kwon , Kwon SU, Lee HJ, Park KA, Seo YS

BACKGROUND: Factors affecting the quality of life (QOL) may be different between young and old stroke patients. However, these issues have not yet been properly investigated. METHODS: We identified 170 young-onset...
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Comparison of the Protective Effect of Indole beta-carbolines and R-(-)-deprenyl Against Nitrogen Species-Induced Cell Death in Experimental Culture Model of Parkinson's Disease

Han YS, Kim JM, Cho JS, Lee CS, Kim DE

BACKGROUND: The membrane permeability transition of mitochondria has been suggested to be involved in toxic and oxidative forms of cell injury. Mitochondrial dysfunction is considered to play a critical role...
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New England Medical Center Posterior Circulation Stroke Registry: I. Methods, Data Base, Distribution of Brain Lesions, Stroke Mechanisms, and Outcomes

Caplan LR, Chung CS, Wityk RJ, Glass TA, Tapia J, Pazdera L, Chang HM, Dashe JF, Chaves CJ, Vemmos K, Leary M, Dewitt LD, Pessin MS

Among 407 New England Medical Center Posterior Circulation Registry (NEMC-PCR) patients, 59% had strokes without transient ischemic attacks (TIAs), 24% had TIAs before strokes, and 16% had only posterior circulation...
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New England Medical Center Posterior Circulation Stroke Registry II. Vascular Lesions

Caplan LR, Wityk RJ, Pazdera L, Chang HM, Pessin MS, DeWitt LD

Among 407 New England Medical Center Posterior Circulation Registry (NEMC-PCR) patients, the extracranial (ECVA) and intracranial vertebral arteries (ICVA) were the commonest sites of severe occlusive disease followed by the...
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