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Current Status of Deceased Donor Liver Transplantation for Alcoholic Liver Disease in Korea in MELD Era

Joo DJ

The organ allocation system should be fair and efficient to predict the prognosis of patients with end-stage organ failure. The liver allocation system in Korea was changed to the model...
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Bone Marrow Chimerism Detection Using Next Generation Sequencing Based on Single Nucleotide Polymorphisms Following Liver Transplantation: Comparison With Short Tandem Repeat-PCR

Kim J, Hwang IS, Kim HS, Joo DJ, Hong KR, Choi JR

No abstract available.
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Verruca Eradication Following Conversion to Sirolimus in a Renal Transplant Recipient after Longstanding Cyclosporine A Treatment

Joo DJ, Kim SH, Huh KH, Kim YS

We present the case of a 50-year-old male kidney transplant recipient whose verruca skin warts completely disappeared after conversion of immunosuppressive treatment from cyclosporine A to sirolimus. Before conversion, the...
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Second hand allotransplantation experience after the revised transplantation law: 5-month follow-up

Kim Y, Hong JW, Lee SJ, Kim SH, Jwa SJ, Joo OY, Mo YW, Suh YC, Choi YR, Joo DJ

Background: Hand transplantation for upper extremity amputation provides a unique treatment that restores form and function. In January 2021, the first hand allotransplantation since legalization was successfully performed. Based on...
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Graft-versus-host disease after simultaneous pancreas-kidney transplantation

Lee J, Kim MS, Huh KH, Joo DJ, Lee JG, Kim SI

Graft-versus-host disease (GVHD) is rare complication after simultaneous pancreas-kidney transplantation (SPK). Here, we present a rare case of GVHD that developed in a SPK recipient. A 38-year-old female patient with...
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Antiplatelet drugs on the recurrence of hepatocellular carcinoma after liver transplantation

Kim DG, Choi MC, Min EK, Lee JG, Joo DJ, Kim MS

Background: Previous studies reported suppressive effects of antiplatelet agents on hepatocellular carcinoma (HCC); however, this has never been assessed in patients who underwent liver transplantation (LT). Methods: This retrospective observational study...
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Curative liver transplantation after lung resection for advanced hepatocellular carcinoma with lung metastasis and inferior vena cava tumor thrombosis: a case report

Joo DJ, Kim DY, Seong J, Kim HJ, Lee JG, Han DH, Choi GH, Kim MS, Choi JS, Kim SI

Hepatocellular carcinoma (HCC) with distant metastasis is an absolute contraindication for liver transplantation (LT). However, it is still unclear whether LT is feasible or acceptable in such patients, albeit after...
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Impact of everolimus on survival after liver transplantation for hepatocellular carcinoma

Kang I, Joo DJ

Background: The objective of this study was to investigate whether everolimus (EVR) use affects long-term survival after liver transplantation (LT) in patients with hepatocellular carcinoma (HCC). Methods: Data from 303 consecutive...
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Clinical association between tacrolimus intra-patient variability and liver transplantation outcomes in patients with and without hepatocellular carcinoma

Kim HJ, Lee JG, Joo DJ, Kim MS, Lee J

Tacrolimus is the mainstay of immunosuppression in liver transplantation to prevent rejection. However, the clinical use of tacrolimus is complicated by its narrow therapeutic window and significant intra-patient variability (IPV)....
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Clinical Characteristics of Focal Segmental Glomerulosclerosis Recurrence after Adult Renal Transplantation

Joo DJ, Lee JJ, Lee BM, Kim MS, Huh KH, Kim SJ, Kim SI, Kim YS

BACKGROUND: Recurrence of focal segmental glomerulosclerosis (FSGS) after kidney transplantation is a frequent and still unpredictable complication. Moreover, risk factors for recurrence have not yet been clearly identified. METHODS: We enrolled...
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Most Transmitted Glomerular Lesions in a Zero-Hour Biopsy of Allograft Kidney Have No Clinical Significance

Lim BJ, Joo DJ, Kim YS, Jeong HJ

BACKGROUND: The clinical significance of glomerular lesions detected in zero-hour renal allograft biopsies have yet to be fully examined. METHODS: We retrospectively reviewed 229 zero-hour renal allograft biopsies, and investigated the...
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Organ procurement in a deceased donor

Hwang HP, Kim JM, Shin S, Ahn HJ, Lee S, Joo DJ, Han SY, Haam SJ, Hwang JK, Yu HC

With the increasing demand for organ transplantation, organ procurement from a deceased donor is an essential step for deceased donor organ transplantation. A proper surgical technique for the procurement of...
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The feasibility of organ transplantation during the COVID-19 outbreak: experiences from South Korea

Lee J, Kim EJ, Ihn K, Lee JG, Joo DJ, Kim MS, Kim SI, Kim YS, Huh KH

Background: The coronavirus disease 2019 (COVID-19) has forced healthcare systems to reduce transplant activities in order to preserve resources and minimize the risk of nosocomial transmission. Although transplantation societies around...
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Differential impact of tacrolimus intra-patient variability on liver transplant outcomes in patients with and without hepatocellular carcinoma

Kim HJ, Lee JG, Joo DJ, Kim MS, Kim SI, Lee J

Background: The recurrence rate for hepatocellular carcinoma (HCC) after liver transplant is high as 15%–20% despite a careful selection of candidates. Although immunosuppression plays an important role in post-transplant HCC...
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Predicted Impact of the Model for End-Stage Liver Disease 3.0 in a Region Suffering Severe Organ Shortage

Kim DG, Yim SH, Min EK, Choi MC, Lee JG, Kim MS, Joo DJ

Background The model for end-stage liver disease 3.0 (MELD3.0) is expected to address the flaws of the current allocation system for deceased donor liver transplantation (DDLT). We aimed to validate MELD3.0...
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Effect of cumulative exposure to tacrolimus on the recurrence of hepatocellular carcinoma after liver transplantation

Kim DG, Lee JG, Joo DJ, Kim MS

Background: Previous studies reported that maintaining at lower trough level of tacrolimus could reduce the recurrence of hepatocellular carcinoma (HCC) after liver transplantation (LT); however, this has never been assessed...
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Clinical impact of myosteatosis in liver transplant recipients

Lee J, Koh HH, Min E, Yim SH, Choi M, Kim DG, Lee JG, Joo DJ

Background: Myosteatosis, excessive intramuscular fat disposition, is common in patients with chronic liver disease and is associated with increased morbidity and mortality. We investigated the effects of pretransplant myosteatosis on...
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Single Center Experience of Biliary Reconstruction in Living Donor Liver Transplantation: Duct-to-Duct Anastomosis

Nam JH, Yang SJ, Lee JG, Joo DJ, Han DH, Choi GH, Choi JS

BACKGROUND: Duct-to-duct anastomosis is the most common biliary reconstruction method in living donor liver transplantation. However, biliary complications can frequently occur. The objective of this study was to examine biliary...
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Antitumor Effect of Low-Dose of Rapamycin in a Transgenic Mouse Model of Liver Cancer

Lee HS, Kim JY, Ro SW, Kim MS, Kim H, Joo DJ

Purpose: We investigate whether low-dose rapamycin is effective in preventing hepatocellular carcinoma (HCC) growth and treating HCC after tumor development in transgenic mice. Materials and Methods: We established transgenic mice with...
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Impact of tacrolimus intra-patient variability on kidney transplant outcomes according to immunologic risk

Kim EJ, Lee J, Kim SJ, Lee JG, Kim BS, Joo DJ, Huh KH, Kim MS, Kim SI, Kim YS

Background: High intra-patient variability (IPV) of tacrolimus trough concentrations is increasingly recognized as a predictor of poor long-term outcomes in kidney transplant recipients. However, there is a lack of information...
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