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Juvenile Patient with LEOPARD Syndrome: Clinical Profile of a Genetically Confirmed Case

Wan P, Cheng Y, Chen Z, Chen J

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Coactosin-like protein 1 inhibits neuronal migration during mouse corticogenesis

Li G, Yin Y, Chen J, Fan Y, Ma J, Huang Y, Chen C, Dai P, Chen S, Zhao S

Coactosin-like protein 1 (Cotl1), a member of the actin-depolymerizing factor (ADF)/cofilin family, was first purified from a soluble fraction of Dictyostelium discoideum cells. Neuronal migration requires cytoskeletal remodeling and actin...
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ERRATUM: Comparison between Craniospinal Irradiation and Limited-Field Radiation in Patients with Non-metastatic Bifocal Germinoma

Li B, Lv W, Li C, Yang J, Chen J, Feng J, Chen L, Ma Z, Li Y, Wang J, Liu Y, Li Y, Liu S, Luo S, Qiu X

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Coexistence of Subcutaneous Panniculitis-Like T-Cell Lymphoma and Dermatomyositis in a 12-Year-Old Boy

Wei R, Liu H, Zhang Z, Chen F, Chen J, Xu Q, Yu H, Liang J, Yao Z

Subcutaneous panniculitis-like T-cell lymphoma (SPTL) is an extremely rare, indolent skin malignancy that can be difficult to distinguish from autoimmune disease-associated panniculitides. Here, we describe a 12-year-old boy who was...
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Rehmannioside D mitigates disease progression in rats with experimental-induced diminished ovarian reserve via Forkhead Box O1/KLOTHO axis

Liang Y, Wang H, Chen J, Chen L, Chen X

This study aims to explore the impact of Rehmannioside D (RD) on ovarian functions of rats with diminished ovarian reserve (DOR) and its underlying mechanisms of action. A single injection...
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Expression and Clinicopathological Significance of CD9 in Gastrointestinal Stromal Tumor

Yang H, Shen C, Zhang B, Chen H, Chen Z, Chen J

This study investigated the expression and clinicopathological significance of CD9 in gastrointestinal stromal tumor (GIST). Immunohistochemistry staining for CD9 was performed on tumor tissues from 74 GIST patients. The correlation...
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Calcium/Calmodulin-dependent Serine Protein Kinase-associated Neuro-gastrointestinal Disorder: First Report of a Patient With Hirschsprung‘s Disease

Tian M, Pan H, Lei W, Chen J, Li J, Lang C, Shu X

  • KMID: 2507124
  • J Neurogastroenterol Motil.
  • 2020 Oct;26(4):556-558.
  • doi: 10.5056/jnm20059
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Intra-Articular Injection of miR-29a-3p of BMSCs Promotes Cartilage Self-Repairing and Alleviates Pain in the Rat Osteoarthritis

Wang Q, Chen Y, Shen X, Chen J, Li Y

BACKGROUND: Stem cells intra-articular injection stagey indicated a potential therapeutic effect on improving the pathological progress of osteoarthritis (OA). However, the long-term effect of stem cells intra-articular injection on the...
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Male hypogonadism caused by a homozygous missense mutation of the LHB gene

Chen J, Yi Wt, Cui YQ, Wang Wt, Wang X

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Cerebellar Structural Abnormality in Autism Spectrum Disorder: A Magnetic Resonance Imaging Study

Lu Q, Chen J, Wang Y, Huang L, Jiang Z, Nguchu BA, Chen S, Qiu B, Wang X

Objective This study uses structural magnetic resonance imaging to explore changes in the cerebellar lobules in patients with autism spectrum disorder (ASD) and further analyze the correlation between cerebellar structural...
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Breviscapine Ameliorates Fear Extinction and Anxiety in BALB/cJ Mice

Liang W, Huang J, Yang S, Huang P, Chen J, Chen C, Yang Q, Li F

Objective In this research, the influence of breviscapine on anxiety, fear elimination, and aggression and the potential mechanism was investigated. Methods Anxiety and locomotion were analyzed by elevated plus maze and...
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Electroacupuncture-Modulated MiR-106b-5p Expression Enhances Autophagy by Targeting Beclin-1 to Promote Motor Function Recovery After Spinal Cord Injury in Rats

Guo S, Chen J, Yang Y, Li X, Tang Y, Gui Y, Chen J, Xu j

Objective: Electroacupuncture (EA) has a definite effect on the treatment of spinal cord injuries (SCIs), but its underlying molecular mechanism remains unclear. Meanwhile, MiR106b-5p is an autophagy- and apoptosis-related microribonucleic...
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Effects of a Death Education Intervention for Older People with Chronic Disease and Family Caregivers: A Quasi-Experimental Study

Chen W, Ma H, Wang X, Chen J

Purpose To investigate the effectiveness of a structured death education program for older adults with chronic illness and their family caregivers. Methods This study adopted two-group, nonrandomized quasi-experimental design. Patient–caregiver dyads in the...
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Spine Fractures of Patients with Ankylosing Spondylitis and Diffuse Idiopathic Skeletal Hyperostosis: Fracture Severity and Injury-Related Mortality at a Level I Trauma Center

Chen SR, Munsch MA, Chen J, Couch BK, Wawrose RA, Oyekan AA, Adjei J, Donaldson WF, Lee JY, Shaw JD

Study Design: Retrospective review of prospectively collected cohort. Purpose: To identify differences in treatment and mortality of spine fractures in patients with ankylosing conditions of the spine. Overview of Literature: Ankylosing...
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Family History, Tobacco Smoking, and Risk of Ischemic Stroke

Fan M, Lv J, Yu C, Guo Y, Bian Z, Yang S, Yang L, Chen Y, Li F, Zhai Y, Wang P, Chen J, Chen Z, Qi L, Li L, on behalf of the China Kadoorie Biobank Collaborative Group

BACKGROUND AND PURPOSE: Both genetic factors and smoking are associated with ischemic stroke (IS) risk. However, little is known about the potential interaction of these factors. We aimed to assess...
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Effects of echinomycin on endothelin-2 expression and ovulation in immature rats primed with gonadotropins

Wang Z, Zhang Z, Wu Y, Chen L, Luo Q, Zhang J, Chen J, Luo Z, Huang X, Cheng Y

  • KMID: 1506225
  • Exp Mol Med.
  • 2012 Oct;44(10):615-621.
Echinomycin is a small-molecule inhibitor of hypoxia-inducible factor-1 DNA-binding activity, which plays a crucial role in ovarian ovulation in mammalians. The present study was designed to test the hypothesis that...
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A New Examination Method for Anatomical Variations of the Flexor Digitorum Superficialis in the Little Finger

Tan J, Kim CH, Lee HJ, Chen J, Chen QZ, Jeon IH

BACKGROUND: Current examination methods to assess the anatomical variations of flexor digitorum superficialis (FDS) tendon in the little finger necessitate a strong external force applied by the examiner and cause...
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Effectiveness of alendronate as an adjunct to scaling and root planing in the treatment of periodontitis: a meta-analysis of randomized controlled clinical trials

Chen J, Chen Q, Hu B, Wang Y, Song J

PURPOSE: Alendronate has been proposed as a local and systemic drug treatment used as an adjunct to scaling and root planing (SRP) for the treatment of periodontitis. However, its effectiveness...
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Comparison between Craniospinal Irradiation and Limited-Field Radiation in Patients with Non-metastatic Bifocal Germinoma

Li B, Lv W, Li C, Yang J, Chen J, Feng J, Chen L, Ma Z, Li Y, Wang J, Liu Y, Li Y, Liu S, Luo S, Qiu X

Purpose Whether craniospinal irradiation (CSI) could be replaced by limited-field radiation in non-metastatic bifocal germinoma remains controversial. We addressed the issue based on the data from our series and the literature....
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The Role and Specific Mechanism of OCT4 in Cancer Stem Cells: A Review

Zhang Q, Han Z, Zhu Y, Chen J, Li W

Recently, evidences show that cancer stem cells (CSCs) are a type of cancer cell group with self-renewal and play a huge role in tumor recurrence, metastasis, and drug resistance. Finding...
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