Endocrinol Metab.  2024 Feb;39(1):90-91. 10.3803/EnM.2024.102.

Younger-Onset Diabetes: Is the Age of Onset More Important than the Duration of Diabetes?

Affiliations
  • 1Division of Endocrinology and Metabolism, Department of Internal Medicine, Yeouido St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea


Figure

  • Fig. 1. Estimates of reduced life expectancy by age at diagnosis of type 2 diabetes compared with people without diabetes. Schematic illustration showing that at the age of 50 years, individuals who were diagnosed with diabetes when they were 30 years old died about 14 years earlier than individuals without diabetes; those diagnosed at the age of 40 years died around 10 years earlier, and those diagnosed at the age of 50 years died around 6 years earlier [1].


Reference

1. Emerging Risk Factors Collaboration. Life expectancy associated with different ages at diagnosis of type 2 diabetes in high-income countries: 23 million person-years of observation. Lancet Diabetes Endocrinol. 2023; 11:731–42.
2. TODAY Study Group; Bjornstad P, Drews KL, Caprio S, Gubitosi-Klug R, Nathan DM, et al. Long-term complications in youth-onset type 2 diabetes. N Engl J Med. 2021; 385:416–26.
3. Trief PM, Kalichman SC, Wang D, Drews KL, Anderson BJ, Bulger JD, et al. Medication adherence in young adults with youth-onset type 2 diabetes: iCount, an observational study. Diabetes Res Clin Pract. 2022; 184:109216.
4. Weinstock RS, Trief PM, Burke BK, Wen H, Liu X, Kalichman S, et al. Antihypertensive and lipid-lowering medication adherence in young adults with youth-onset type 2 diabetes. JAMA Netw Open. 2023; 6:e2336964.
5. Cho Y, Park HS, Huh BW, Seo SH, Seo DH, Ahn SH, et al. Prevalence and risk of diabetic complications in young-onset versus late-onset type 2 diabetes mellitus. Diabetes Metab. 2022; 48:101389.
6. Chan JC, Lau ES, Luk AO, Cheung KK, Kong AP, Yu LW, et al. Premature mortality and comorbidities in young-onset diabetes: a 7-year prospective analysis. Am J Med. 2014; 127:616–24.
7. Baek HS, Park JY, Yu J, Lee J, Yang Y, Ha J, et al. Characteristics of glycemic control and long-term complications in patients with young-onset type 2 diabetes. Endocrinol Metab (Seoul). 2022; 37:641–51.
8. Cosentino F, Grant PJ, Aboyans V, Bailey CJ, Ceriello A, Delgado V, et al. 2019 ESC guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD. Eur Heart J. 2020; 41:255–323.
9. Choi JH, Lee KA, Moon JH, Chon S, Kim DJ, Kim HJ, et al. 2023 Clinical practice guidelines for diabetes mellitus of the Korean Diabetes Association. Diabetes Metab J. 2023; 47:575–94.
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