J Breast Dis.  2023 Dec;11(2):53-58. 10.14449/jbd.2023.11.2.53.

The Subcutaneous Variant Dermatofibrosarcoma Protuberans of the Breast With Nipple Areolar Complex Invasion Treated With Central Lumpectomy: A Case Report

Affiliations
  • 1Departments of Surgery, Chonnam National University Medical School and Chonnam National University Hwasun Hospital, Hwasun-gun, Korea
  • 2Departments of Radiology, Chonnam National University Medical School and Chonnam National University Hwasun Hospital, Hwasun-gun, Korea
  • 3Departments of Pathology, Chonnam National University Medical School and Chonnam National University Hwasun Hospital, Hwasun-gun, Korea
  • 4Department of Surgery, Chonnam National University Medical School and Chonnam National University Hospital, Gwangju, Korea

Abstract

Dermatofibrosarcoma protuberans (DFSP) is a rare low-grade soft tissue sarcoma and the breast is less commonly affected than the torso. DFSP can be misdiagnosed as neurofibroma, desmoid tumor, malignant melanoma, or Kaposi sarcoma. A variant of DFSP originates from the subcutaneous layer and is called subcutaneous variant dermatofibrosarcoma protuberans (SC-DFSP). It can be easily confused with breast phyllodes tumor, myofibroblastoma, myoepithelioma, or advanced breast cancer, such as fibromatosis-like metastatic carcinoma. Following punch biopsy, the treatment of choice for breast DFSP is complete excision with negative margins ≥ 2 cm. We present a case of breast SC-DFSP with nipple areolar complex invasion.

Keyword

Breast; Dermatofibrosarcoma protuberans; Nipple; Subcutaneous tissue
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