Ann Clin Microbiol.  2022 Sep;25(3):103-109. 10.5145/ACM.2022.25.3.5.

The First Case of Bacteremia Caused by Bordetella hinzii in Korea

• Yu J
• Kim S
• Hur KH
• Sung H
• Kim MN

• KMID: 2533948
• DOI: http://doi.org/10.5145/ACM.2022.25.3.5

Abstract

Bordetella hinzii is a nonfermenting, gram-negative rod and a rare opportunistic pathogen that can cause respiratory infections, bacteremia, and cholangitis. Here, we report the first case of bacteremia caused by B. hinzii in Korea. A 59-year-old man was admitted for the biopsy of a mass lesion in the left lower lobe, which was detected during a health screening. The blood cultures collected from the patient with high fever (> 39℃), which developed 4 hours after the biopsy, yielded gram-negative rods. The gram-negative bacilli were identified as B. hinzii using matrix-assisted laser desorption ionization time-of-flight mass spectrometry and PCR sequencing of the 16S rRNA gene. After 9 days of antimicrobial treatment with ampicillin/sulbactam, piperacillin/tazobactam, or meropenem, the patient improved and was discharged.

Keyword

Bacteremia; Biopsy; Bordetella hinzii; Bronchoscopy

Figure

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  Fig. 1. Flowchart determining convalescence and early infection in newly diagnosed SARS-CoV-2 cases by SARS-CoV-2 PCR and antibody tests. Ct, cycle of threshold; PCR, polymerase chain reaction.

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  Fig. 2. Trends of Ct values of 31 patients with follow-up SARS-CoV2-PCR tests (A) and comparison of the severity of COVID-19 between patients in convalescent period and patients in early infection period (B). The trend lines of the recovery period were indicated by solid lines, and the trend lines of the early infection period were indicated by dotted lines. Ct, cycle of threshold; PCR, polymerase chain reaction.

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