Blood Res.  2018 Mar;53(1):83-87. 10.5045/br.2018.53.1.83.

A case of adult T-cell leukemia/lymphoma in Korea

• Lee YM
• Kim JM

• KMID: 2414371
• DOI: http://doi.org/10.5045/br.2018.53.1.83

Abstract

No abstract available.

MeSH Terms

Adult*
Humans
Korea*
T-Lymphocytes*

Figure

• 

  Fig. 1 Dermatic presentation and radiologic evaluations. The patient showed multiple erythematous patches on his back (A). CT scan revealed multiple enlarged cervical lymph nodes (B) with remarkable hepatosplenomegaly (C).

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  Fig. 2 Microscopic and immunohistochemical staining features. Medium-sized atypical lymphoid cells totally replaced a lymph node (A) (Haematoxylin-eosin stain, ×400) with strong positivity of CD3, CD4, and Ki-67 labeling index (B–D). On the skin biopsy, atypical lymphoid cells showed typical epidermotropism (E) (Haematoxylin-eosin stain, ×200), and massive perivascular infiltration (F) (Haematoxylin-eosin stain, ×200) resembling Mycosis fungoides. A strong positivity of CD4 and Ki-67 labeling index were shown (G, H). Atypical lymphoid cell infiltration was evident in his liver biopsy (I) (Haematoxylin-eosin stain, ×100) with strong CD4 reactivity (J). The same findings were noted in his bone marrow biopsy (K) (Haematoxylin-eosin stain, ×200) with CD4 immunohistochemical study (L). The HTLV-1 infected ‘flower cells’ were apparent in his peripheral blood smear (Wright-Giemsa ×1,000) (M–P).

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