J Korean Ophthalmol Soc.  2011 Nov;52(11):1366-1369.

A Case of Fungal Keratitis Caused by Drechslera Species

• Kim CR
• Seo SW
• Park JM
• Yoo JM
• Han YS
• Kim S
• Kim SJ

Abstract

PURPOSE
To report a case of fungal keratitis caused by Drechslera species.
CASE SUMMARY
A 77-year-old man visited our clinic complaining of left ocular pain and decrease of visual acuity for 1 week On slit-lamp examination, epithelial defect and stromal infiltration on the corneal center with numerous inflammatory cells in the anterior chamber were found. There was no improvement after routine antibiotic treatment. A corneal biopsy and culture were performed on the corneal lesion. The KOH smear study reported hyphae, thus the patient was treated with 0.25% amphotericin B, 0.2% fluconazole and 5% natamycin eye drops. A clinical improvement was observed on the corneal lesion and Drechslera species was identified by the culture study.
CONCLUSIONS
The authors report an experience of fungal keratitis caused by Drechslera species.

Keyword

Drechslera; Fungal keratitis; Natamycin

MeSH Terms

Aged
Amphotericin B
Anterior Chamber
Biopsy
Fluconazole
Humans
Hyphae
Keratitis
Natamycin
Ophthalmic Solutions
Visual Acuity
Amphotericin B
Fluconazole
Natamycin
Ophthalmic Solutions

Figure

• 

  Figure 1. On the first day the patient visited our clinic epithelial defect and corneal stromal infiltration is located in the center of the cornea. There is no hypopyon.

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  Figure 2. Twenty days after first visit, epithelial defect, whitish elevated corneal lesion is detected. Stromal infiltration lesion has enlarged.

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  Figure 3. Photograph of corneal biopsy specimen shows abundant hyphae (H&E, ×200).

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  Figure 4. On the fifteenth hospital day, the lesion of the corneal stroma is clear. Hypopyon disappeared.

Reference

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