Korean J Dermatol.
2010 Mar;48(3):240-242.
A Case of Primary Syphilis on Both Oral Angles
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- 1Department of Dermatology, College of Medicine, Korea University, Seoul, Korea. gold2000@nate.com
Abstract
- Primary syphilis affects the genital and, less frequently, the extragenital regions. Approximately two-thirds of extragenital chancres occur above the neck, and about one-half of these are seen on the lips, the perioral region, or in the oral cavity. We present a case of a 32-year-old woman with a 2-month history of discharging ulcers on both oral angles. She had a history of orogenital sexual contact. Serologic tests for syphilis was positive, particularly the VDRL (1:128), confirmed by TPHA. The biopsy specimen showed a predominant infiltration of plasma cells in the dermis. The skin lesions improved after 4 weeks treatment with doxycycline.
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