Korean J Perinatol.  2013 Jun;24(2):89-94. 10.14734/kjp.2013.24.2.89.

Comparison of Clinical Findings of Gastric Perforation between Preterm and Term Neonates

• Kim EH
• Kang KJ
• Kim CS
• Lee SL
• Jung E
• Choi SO
• Park WH

• KMID: 2280925
• DOI: http://doi.org/10.14734/kjp.2013.24.2.89

Abstract

PURPOSE
The purpose of this study was to compare the clinical findings and mortality of gastric perforation between preterm and term infants.
METHODS
The medical records of neonates, admitted to the neonatal intensive care unit of Dongsan Medical Center for gastric perforation between July 1992 and June 2012, were reviewed retrospectively. The admission records of clinical findings and mortality were reviewed and statistically analyzed between preterm and term infants.
RESULTS
Nine infants were diagnosed with neonatal gastric perforation. Of the nine infants, the number of term infants was five and the number of male was eight. Of the four infants diagnosed with spontaneous gastric perforation, the number of preterm and term infants was three and one respectively. The anatomical location of perforation was greater curvature in all four preterm infants. However, various sites such as greater curvature (three infants) and antrum (two infants) were observed in five term infants. Mortality rate was tended to be lower in preterm infants compared to term infants, without statistical significance (25.0% vs. 40.0%, P>0.1). There was no mortality in four infants diagnosed with spontaneous gastric perforation. However, two infants diagnosed with necrotizing enterocolitis (NEC) all died.
CONCLUSION
There was no significant difference in clinical findings and mortality of gastric perforation between preterm and term infants. The prognosis of spontaneous gastric perforation was good, however, mortality rate was tended to be higher in NEC than other causes (P=0.083).

Keyword

Gastric Perforation; Neonate; Preterm infant; Term infant

MeSH Terms

Enterocolitis, Necrotizing
Humans
Infant
Infant, Newborn
Infant, Premature
Intensive Care, Neonatal
Male
Medical Records
Prognosis
Retrospective Studies

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