Korean J Otorhinolaryngol-Head Neck Surg.  2008 Dec;51(12):1170-1173.

Sclerosing Mucoepidermoid Carcinoma of the Parotid Gland

• Hong SW
• Lee BC
• Lee JS
• Koh JS

Abstract

Sclerosing mucoepidermoid carcinoma of salivary gland is a rare variant of mucoepidermoid carcinoma and can be confused with benign condition on clinical, radiological, and pathologic examination. A 34-year old female was found to have a parotid mass with a long history. Preoperative evaluation including computed tomography and fine needle aspiration cytology were nondiagnostic. Intraoperatively, frozen section specimens showed only low grade tubular lesion with severe background inflammatory infiltration. Final pathological examination demonstrated multiple cystic nests composed of mucinous and squamoid intermediate cells within the background of central dense, sclerotic, collagenized stroma and peripheral inflammatory infiltrate, consistent with a low grade sclerosing mucoepidermoid carcinoma. Sclerosing mucoepidermoid carcinoma is a very rare salivary gland tumor with an uncertain clinical behavior. Complete surgical excision with tumor-free margins is recommended. Postoperative radiation therapy is suggested for positive or close margins, and close follow-up of the patients is mandatory.

Keyword

Mucoepidermoid carcinoma; Sclerosis; Parotid gland

MeSH Terms

Biopsy, Fine-Needle
Carcinoma, Mucoepidermoid
Collagen
Female
Follow-Up Studies
Frozen Sections
Humans
Mucins
Parotid Gland
Salivary Glands
Sclerosis
Collagen
Mucins