Korean J Otolaryngol-Head Neck Surg.
2005 Jan;48(1):109-113.
A Case of Extramedullary Plasmacytoma of the Nasopharynx
- Affiliations
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- 1Department of Otolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea, Seoul, Korea. entckj@catholic.ac.kr
Abstract
- Multiple myeloma, solitary bone plasmacytoma, extramedullary plasmacytoma, plasmablastic sarcoma, and multifocal form of multiple myeloma belong to plasma cell tumors. Among them, extramedullary plasmacytoma consists of 4% of all plasma cell tumors and is found predominantly in the head and neck region. This tumor is a solitary tumor consisting of monoclonal plasma cell proliferation that occurs in soft tissues other than bone. The frequent sites in the upper aerodigestive tract are the paranasal sinus and the nasal cavity. Because the diagnosis is based on immunophenotypical finding of monoclonal plasma cells and there are many differential diagnoses, the exact diagnosis is difficult. To our knowledge, extramedullary plasmacytoma originating in the nasopharynx has rarely been reported. We experienced a case of nasopharyngeal extramedullary plasmacytoma which was treated with combined therapy. So we report this case with a review of literatures.
