Ann Dermatol.  2013 Nov;25(4):522-523. 10.5021/ad.2013.25.4.522.

Activation Markers CD63 and CD203c Are Upregulated in Chronic Urticaria

• Christensen CU
• Vestergaard C
• Hoffmann H

• KMID: 2265083
• DOI: http://doi.org/10.5021/ad.2013.25.4.522

Abstract

No abstract available.

MeSH Terms

Urticaria*

Figure

• 

  Fig. 1 Changes in marker expression between patients and controls. MFI: median fluorescence intensity, C: controls, P: patients.

Reference

1. Zuberbier T, Asero R, Bindslev-Jensen C, Walter Canonica G, Church MK, Giménez-Arnau A, et al. Dermatology Section of the European Academy of Allergology and Clinical Immunology. Global Allergy and Asthma European Network. European Dermatology Forum. World Allergy Organization. EAACI/GA(2)LEN/EDF/WAO guideline: definition, classification and diagnosis of urticaria. Allergy. 2009; 64:1417–1426.

2. Konstantinou GN, Asero R, Maurer M, Sabroe RA, Schmid-Grendelmeier P, Grattan CE. EAACI/GA(2)LEN task force consensus report: the autologous serum skin test in urticaria. Allergy. 2009; 64:1256–1268.

3. Gentinetta T, Pecaric-Petkovic T, Wan D, Falcone FH, Dahinden CA, Pichler WJ, et al. Individual IL-3 priming is crucial for consistent in vitro activation of donor basophils in patients with chronic urticaria. J Allergy Clin Immunol. 2011; 128:1227–1234.

4. Lourenço FD, Azor MH, Santos JC, Prearo E, Maruta CW, Rivitti EA, et al. Activated status of basophils in chronic urticaria leads to interleukin-3 hyper-responsiveness and enhancement of histamine release induced by anti-IgE stimulus. Br J Dermatol. 2008; 158:979–986.

5. Hansen S, Dahl R, Hoffmann HJ. Determination of blood leukocyte concentration with constant volume acquisition on a flow cytometer is comparable to individualized single platform testing with beads as internal reference standard. J Immunol Methods. 2008; 338:58–62.

6. Grattan CE, Dawn G, Gibbs S, Francis DM. Blood basophil numbers in chronic ordinary urticaria and healthy controls: diurnal variation, influence of loratadine and prednisolone and relationship to disease activity. Clin Exp Allergy. 2003; 33:337–341.

7. Vasagar K, Vonakis BM, Gober LM, Viksman A, Gibbons SP Jr, Saini SS. Evidence of in vivo basophil activation in chronic idiopathic urticaria. Clin Exp Allergy. 2006; 36:770–776.

8. Gibbs BF, Papenfuss K, Falcone FH. A comparison of procedures for purifying human basophils to near homogeneity. Inflamm Res. 2008; 57:Suppl 1. S11–S12.