Diagnostic and Therapeutic Significance of Conization of the Cervix in Patients with Cervical Intraepithelial Neoplasm

Oh, H Y; Park, C H

Abstract

OBJECTIVE
The objective of this study was to evaluate the diagnostic and therapeutic significance of conization of the cervix in patients with cervical intraepithelial neoplasm. Study design: Cold-Knife conization was performed in total 34 patients from August 1994 to April 1997 using "Traditional broad deep cone method". The results of cervical cytology, cervical histology and colposcopic examination were studied in comparison with the pathologic diagnosis of conization specimens and follow-up check examinations of the patients.
RESULTS
Followings are the results summarized. 1. The rate of agreement and underdiagnosis between cervical cytology and conization were 52.9% and 23.5% respectively. 2. The rate of agreement and underdiagnosis between cervical histology and conization were 47.4% and 26.3% respectively. 3. Subsequent hysterectomy was done in 32.4% and the rate of residual disease was 17.6%. 4. The rate of clear resection margin was 88.2% and the rate of positive resection margin and positive endocervical margin were 5.9% and 5.9% respectively. 5. Overall complications of conization were 8.8% : bleeding, infection, and cervical stenosis. 6. Follow-up cervical cytology after conization were within normal limits in 88.2% and ASCUS (atypical squamous cells of undetermined significance) in 11.8%. 7. The mean size and volume of conization specimen were 3.0x2.4x1.4 cm and 11.5 cm3.
CONCLUSION
We conclude that there are diagnosic and therapeutic significance of conization of the cervix in patients with cervical intraepithelial neoplasm.