Korean J Dermatol.  2007 Nov;45(11):1202-1205.

A Case of Linear IgA Bullous Dermatosis Probably Caused by Captopril

• Kwon YS
• Oh SH
• Jung JY
• Ryu DJ
• Lee JH

Abstract

Linear IgA bullous dermatosis (LABD) is a rare autoimmune subepidermal bullous disease characterized by a linear pattern of IgA deposition along the basement membrane zone. The etiology of LABD is unknown but a minority of cases are drug-induced. Although vancomycin is the agent most commonly implicated in the pathogenesis of drug-induced LABD, association with other agents including phenytoin, piroxicam, captopril, diclofenac sodium and cyclosporine have also been reported. We describe a case of linear IgA bullous dermatosis which probably developed after captopril treatment in a 51-year-old male patient with infective endocarditis.

Keyword

Captopril; Linear IgA bullous dermatosis (LABD)

MeSH Terms

Basement Membrane
Captopril*
Cyclosporine
Diclofenac
Endocarditis
Humans
Immunoglobulin A
Linear IgA Bullous Dermatosis*
Male
Middle Aged
Phenytoin
Piroxicam
Vancomycin
Captopril
Cyclosporine
Diclofenac
Immunoglobulin A
Phenytoin
Piroxicam
Vancomycin