Korean J Med Mycol.
2011 Dec;16(4):186-195.
Comparison of Therapeutic Efficacy between Lateral Type of Distal and Lateral Subungual Onychomycosis (DLSO) and Non-lateral Types of DLSO
- Affiliations
-
- 1Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea. bkcho@catholic.ac.kr
Abstract
- BACKGROUND
Onychomycosis is a common fungal infection accounting for 50% of all nail disorders. Above all the clinical types of onychomycosis, distal and lateral subungual onychomycosis (DLSO) is the most common clinical type seen up to 70~90% in onychomycosis patients. Even though the cure rate and recurrence rate of DLSO are considered to be different according to the clinical type of DLSO. Clinical experience, there is a few clinical study showing the difference.
OBJECTIVE
This is to investigate the therapeutic efficacy of lateral type of DLSO comparing with the other types of DLSO.
METHODS
We reviewed 81 DLSO cases who visited our clinic from June 1st, 2006 to June 31st, 2010, and classified them into 2 groups; lateral type and non-lateral types including edge, distal and linear type. We treated the patients with oral antifungal agent for 4 months, and followed them up in 2 months. Scoring clinical index for onychomycosis (SCIO) was checked and photography was taken before treatment and after treatment.
RESULTS
There are no significant differences in average age and male to female ratio between lateral DLSO and non-lateral DLSO. The comparison of SCIO score distribution before treatment between lateral DLSO and non-lateral DLSO showed no significant statistical difference. However, there was significant change in SCIO score distribution after the treatment. Decreased SCIO score in lateral DLSO was 6.99, while non-lateral DLSO was 11.1 (p=0.018). There was 2cases worsen cases in lateral DLSO, while there was no worsen case in non-lateral DLSO (p=0.019).
CONCLUSION
Lateral DLSO is more difficult to treat than non-lateral DLSO.
