Korean J Dermatol.  1988 Jun;26(3):330-337.

Histopathologic Study of Erythema Nodosum: Licke Lesions in Behcet's Disease

Abstract

A histopathological study of erythema nodosum-like lesions in Behcet's disease was performed on 55 patients with incomplete and suspect types of Behcet's disease. Relatively common characteristics in histopathology of erythema nodosum-like lesions could be found in the patients with incomplete type of Behcet's disease. The histopathologic findings of erythema nodosum-like lesions in 21 patients with incomplete type of Behcet's disease were as follows : l. A moderate lymphocytic infiltration was found around the blood vessels and the sweat glands in the dermis. In the subcutaneous tissue, besides lymphohistiocytic infiltration, neutrophils were present in significant number in 9 cases (42.9%) 2. Vasculitis of small vessels was found within the periphery of fat lobules in 7 cases (81.0%), Five cases (23.8%) also showed thrombophlebitis. Seven cases (33.3%) showed histiocytic granuloma formation within the fat lobules. Microabscess formation in the subcutaneous tissue was seen in 5 cases (23.8 %), but it was not certain whether this was the charateristic feature.


MeSH Terms

Blood Vessels
Dermis
Erythema Nodosum*
Erythema*
Granuloma
Humans
Neutrophil Infiltration
Subcutaneous Tissue
Sweat Glands
Thrombophlebitis
Vasculitis
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