J Korean Soc Ther Radiol.  1990 Jun;8(1):95-102.

The Role of Radiation Therapy in Adenocarcinoma of Endometrium

• Yun HG
• Ha SW
• Kang SB
• Lee HP

Abstract

From May, 1979 to October, 1987, 38 patients with endometrial carcinoma were treated with radiotherapy at Seoul National University Hospital. Of these, 32 patients received radiotherapy postoperatively, one received radiotherapy preoperatively, and five received radiotherapy only. Relative frequencies of obesity, nulliparity, late menopause, diabetes mellitus and hypertension were all higher than those reported in normal women in Korea, and those of obesity, diabetes mellitus, and nulliparity were significantly high. The overall actuarial five-year survival rate was 75.6%. The overall actuarial five year survival rates of stage I(22 cases), stage II(six cases), and stage III(10 cases) were 90.0%, 80.0%, and 44.4%, respectively, and were significantly different from each other. Among various factors, stage only proved to be prognostic by multivariate analysis. There were two local failures, three local failures combined with distant metastasis, and three distant metastasis. Stages Iand II could be adequately controlled by local modalities without severe complications, stage III endometrial carcinoma might need more aggressive treatment for better survival.

Keyword

Radiation therapy; Adenocarcinoma of endometrium

MeSH Terms

Adenocarcinoma*
Diabetes Mellitus
Endometrial Neoplasms
Endometrium*
Female
Humans
Hypertension
Korea
Menopause
Multivariate Analysis
Neoplasm Metastasis
Obesity
Parity
Radiotherapy
Seoul
Survival Rate