Infect Chemother.  2016 Mar;48(1):61-69. 10.3947/ic.2016.48.1.61.

Guidelines for the Laboratory Diagnosis of Middle East Respiratory Syndrome Coronavirus in Korea

Affiliations
  • 1Department of Laboratory Medicine, Catholic Kwandong University College of Medicine, Incheon, Korea.
  • 2Department of Laboratory Medicine and Genetics, Sungkyunkwan University School of Medicine, Seoul, Korea.
  • 3Department of Laboratory Medicine, University of Ulsan College of Medicine, Seoul, Korea. mnkim@amc.seoul.kr
  • 4Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul, Korea.
  • 5Department of Laboratory Medicine, Seoul National University College of Medicine, Seoul, Korea.
  • 6Department of Laboratory Medicine, Hallym University College of Medicine, Seoul, Korea.
  • 7Department of Laboratory Medicine, Chung-Ang University College of Medicine, Seoul, Korea.

Abstract

The recent outbreak of Middle East respiratory syndrome (MERS) in Korea was unexpected that laboratory response had to be built up urgently during the outbreak. The outbreak was almost all healthcare-associated, which was aggravated by lack of availability in laboratory diagnosis of MERS-CoV on site. On behalf of the MERS joint public and private sector response committee (MERS Joint committee), the Korean Society for Laboratory Medicine (KSLM) launched a MERS response task force (MERS KSLM TF) to facilitate clinical laboratories set up MERS molecular diagnosis. MERS TF established guidelines for laboratory diagnosis of MERS-CoV and provided it to all participating laboratories as the official guidance of MERS Joint committee. This guideline was used for procedure manual of molecular diagnosis of MERS-CoV and laboratory safety manual.

Keyword

Middle East Respiratory Syndrome Coronavirus; The Korean Society for Laboratory Medicine; Task force; Molecular diagnosis; Guideline

MeSH Terms

Advisory Committees
Clinical Laboratory Techniques*
Coronavirus*
Diagnosis
Joints
Korea*
Middle East*
Private Sector

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Reference

1. Korea Centers for Disease Control and Prevention (KCDC). Guidelins for MERS-CoV control. 3-3ed. Osong: KCDC;2015.
2. World Health Organization (WHO). Laboratory testing for Middle East Respiratory Syndrome Coronavirus: Interim recommendations (revised). Acessed 12 October 2015. Available at: http://www.who.int/csr/disease/coronavirus_infections/WHO_interim_recommendations_lab_detection_MERSCoV_092014.pdf.
3. Centers for Disease Control and Prevention (CDC). Interim guidelines for collecting, handling, and testing clinical specimens from patients under investigation (PUIs) for Middle East Respiratory Syndrome Coronavirus (MERS-CoV) - Version 2.1. Accessed 12 October 2015. Available at: http://www.cdc.gov/coronavirus/mers/downloads/guidelines-clinical-specimens.pdf.
4. European Centre for Disease Prevention and Control (ECDC). Factsheet for health professionals. Accessed 12 October 2015. Available at: http://ecdc.europa.eu/en/healthtopics/coronavirus-infections/mers-factsheet/Pages/default.aspx.
5. Drosten C, Meyer B, Müller MA, Corman VM, Al-Masri M, Hossain R, Madani H, Sieberg A, Bosch BJ, Lattwein E, Alhakeem RF, Assiri AM, Hajomar W, Albarrak AM, Al-Tawfiq JA, Zumla AI, Memish ZA. Transmission of MERS-coronavirus in household contacts. N Engl J Med. 2014; 371:828–835.
Article
6. World Health Organization (WHO). Laboratory biosafety manual: Third edition. Accessed 12 October 2015. Available at: http://www.who.int/csr/resources/publications/biosafety/Biosafety7.pdf?ua=1.
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