Ann Dermatol.  2015 Dec;27(6):780-781. 10.5021/ad.2015.27.6.780.

Diffuse Cutaneous Melanosis Associated with Malignant Melanoma

Affiliations
  • 1Department of Dermatology, University Hospital Zurich, Zurich, Switzerland. johanna.mangana@ usz.ch

Abstract

No abstract available.


MeSH Terms

Melanoma*
Melanosis*

Figure

  • Fig. 1 Sagittal magnetic resonance image showing diffuse bone metastases with pathological fractures, metastases in L5 with penetration of the rear edge and epidural fat tissue, and compression of the S1 nerve.

  • Fig. 2 Brown-gray hyperpigmentation of sun-exposed skin areas because of disease progression. (A) Before onset of diffuse cutaneous melanosis (DCM). (B) After onset of DCM.


Reference

1. Wagner E. Fall von combination eines pigmentkrebs mit einer reinen pigmentgewulst. Arch Heilkunde. 1864; 5:280–284.
2. Neuhaus I, Grekin R. Mammary and extramammary Paget disease. In : Goldsmith LA, Katz SI, Gilchrest BA, Paller AS, Leffell DJ, Wolff K, editors. Fitzpatrick's dermatology in general medicine. 7th ed. New York: McGraw-Hill;2008. p. 1094–1198.
3. Lerner AB, Moellmann G. Two rare manifestations of melanomas: generalized cutaneous melanosis and rapid solar induction of showers of small pigmented lesions. A critical review of the literature and presentation of two additional cases. Acta Derm Venereol. 1993; 73:241–250.
4. Sebaratnam DF, Venugopal SS, Frew JW, McMillan JR, Finkelstein ER, Martin LK, et al. Diffuse melanosis cutis: a systematic review of the literature. J Am Acad Dermatol. 2013; 68:482–488.
Article
5. Böhm M, Schiller M, Nashan D, Stadler R, Luger TA, Metze D. Diffuse melanosis arising from metastatic melanoma: pathogenetic function of elevated melanocyte peptide growth factors. J Am Acad Dermatol. 2001; 44:747–754.
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