Korean J Dermatol.  1987 Jun;25(3):326-333.

Nonsurgical Nail Avulsion in treatment of Onychomycosis

Abstract

The important prerequisite for treatrnent of onychomycosis is the removal of as rnuch fungus-infected nail material as possible. Nincty-five patients with anychomycosis were treated with using urea preparations under occlusive dressings. The urea preparations were quite successful in maceraing the nail plate from the nail bed, allowing the easy removaI of diseased nails in all cases except one. The urea preparations removed only abnormal nail. Completely normal nail was unaffected. After nail avulsion, 95 patients were treated for 6 months with combination clotrimazole and ketoconazcile(group A), or with clotrimazole only(group B). Of the 38 patients in group A who complcted the treatment, 25(65.8%) were cured 6 months later by clinical and mycological criteria, compared to 20(47.6%) of 42 patieries in group B.

Keyword

Onychomycosis; Urea; Nail avulsion; Ketoconazole; Clotrimazole

MeSH Terms

Clotrimazole
Humans
Ketoconazole
Nails, Malformed
Occlusive Dressings
Onychomycosis*
Urea
Clotrimazole
Ketoconazole
Urea
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