Korean J Nephrol.
2005 Jul;24(4):631-637.
A Case of Goodpasture's Syndrome
- Affiliations
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- 1Division of Nephrology and Hypertension, Department of Internal Medicine, Inha University College of Medicine, Incheon, Korea. nhkimj@inha.ac.kr
- 2Kidney Disease Research Group, Inha University College of Medicine, Incheon, Korea.
- 3Departement of Pathology, Inha University College of Medicine, Incheon, Korea.
Abstract
- Goodpasture's syndrome is an autoimmune disease characterized by rapid progressive glomerulonephritis, alveolar hemorrhage and autoantibody to the NC1 domain of the alpha 3 chain of type IV collagen (anti-glomerular basement membrane antibody). It was common in Europe with peak incidence at third decades. However, Goodpasture's syndrome was reported only three cases in Korea. We reported a case of Goodpasture's syndrome in a 34 year old male. He admitted our hospital due to dyspnea and hemoptysis. We made diagnosis by detection of Anti-GBM Ab and biopsy of kidney. He was treated with hemodialysis, plasma exchanges and immunosuppressive agents. However, his renal function was not recovered. Currently, he is receiving regular hemodialysis.
Keyword
MeSH Terms
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Acute Kidney Injury
Adult
Anti-Glomerular Basement Membrane Disease*
Autoimmune Diseases
Basement Membrane
Biopsy
Collagen Type IV
Diagnosis
Dyspnea
Europe
Glomerulonephritis
Hemoptysis
Hemorrhage
Humans
Immunosuppressive Agents
Incidence
Kidney
Korea
Male
Plasma Exchange
Renal Dialysis
Collagen Type IV
Immunosuppressive Agents
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