J Korean Ophthalmol Soc.
1990 Mar;31(3):297-301.
Extracellular Matrix in Human Trabecular Meshwork
- Affiliations
-
- 1Department of Ophthalmology, School of Medicine, Hanyang University, Seoul, Korea.
Abstract
- This study was performed to evaluate the distribution of extracellular matrix in the normal human trabecular meshwork. The trabecular meshworks obtained from 5 enucleated eyes due to traumatic eye-ball rupture were frozen processed, stained with monoclonal antibodies for fibronectin and type IV collagen, and observed by fluorescent microscopy. The indirect immunofluorescent study showed strong positive reactions in the subendothelial basement membrane for fibronectin and type IV collagen and negative reaction in the central core of trabecular beam. These results suggest that fibronectin and type IV collagen distribute predominantly in the basement membrane of the trabecular beam.
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Distribution of proteoglycans in the human trabecular meshwork: histochemical electron microscopic findings with cuprolinic blue
- The Effect of Accumulation of Mutant Myocilins in Human Trabecular Meshwork Cells
- Adenovirus Vector-mediated Gene Transfer into Human Trabecular Cell
- Age-related Changes of the Cellularity and Acid Mucopolysaccharides in the Trabecular Meshwork of the Normal Korean
- Fibronectin in the Trabecular Meshwork: Immunofluorescent and Immunoeledron Microscopic Findings
