J Korean Ophthalmol Soc.  1987 Feb;28(1):31-36.

Pathogens of Corneal Ulcer (II)

• Lee JH
• Jung YC

Abstract

One hundred and thirty-two cases(132 eyes) of corneal ulcer were analysed on the clinical and etiologic basis. The history of evident ocular trauma was found in 28.8% of the cases and ocular disease was found in 7.6% of the cases. Positive results were 16/55 in smear and 33/61 in culture, and the most common isolate was coagulase negative staphylococcus in bacteriologic studies. In fungal studies, positive results were 1/42 in smear and 5/42 in culture, and Aspergillus was the most common isolate. Cephalexin was the most sensitive antibiotics for Gram positive organism and carbenicillin and gentamicin were the most sensitive antibiotics for Gram negative orgamsm. These results indicate that gentamicin and cephalexin in combination would be recommended as the initial treatment of wide-spectrum antibiotics coverage for bacterial corneal ulcer until the final culture results and senitivity are available.

MeSH Terms

Anti-Bacterial Agents
Aspergillus
Carbenicillin
Cephalexin
Coagulase
Corneal Ulcer*
Gentamicins
Staphylococcus
Anti-Bacterial Agents
Carbenicillin
Cephalexin
Coagulase
Gentamicins