J Korean Pediatr Cardiol Soc.  2005 Dec;9(2):342-349.

Assessment of Ventricular Function Using Tissue Doppler Imaging in Kawasaki Disease

• Jang MW
• Park JR
• Eun LY

Abstract

PURPOSE
The purpose of this study is to evaluate ventricular functional changes in Kawasaki disease using tissue Doppler echocardiographic measures with conventional echocardiographic measures.
METHODS
Tissue Doppler imaging and conventional Doppler echocardiography were performed in 69 patients with Kawasaki disease and 39 healthy children. Peak velocities of systolic(Sa) and early(Ea), late(Aa) diastolic motion of mitral annulus were obtained at the lateral and septal side from apical 4 chamber view.
RESULTS
Sa(7.7+/-1.8 cm/s vs 8.8+/-2.1 cm/s, P=0.01) and Ea(15.7+/-3.2 cm/s vs 17.2+/-3.3 cm/s, P=0.03) measured at lateral mitral annulus were significantly lower in patients with Kawasaki disease. Aa(7.0+/-2.0cm/s vs 6.2+/-1.3 cm/s, P=0.01) measured at septal mitral annulus were statistically higher in patients with Kawasaki disease. There was no significant difference in coronary arteriopathy patients compared with non-coronary arteriopathy patients in Kawasaki disease. In conventional mitral and pulmonary venous flow velocities, there was significant difference of E in Kawasaki disease patients. The ratio of E/Ea and flow propagation velocity(Vp) demonstrated difference in Kawasaki disease patients.
CONCLUSION
Peak mitral annular velocities obtained by tissue Doppler imaging were significantly altered in acute phase of Kawasaki disease. Tissue Doppler imaging with conventional Doppler echocardiography can be a promising method for evaluation of ventricular function in patients with Kawasaki disease.

Keyword

Tissue Doppler imaging; Kawasaki disease; Ventricular function

MeSH Terms

Child
Echocardiography
Echocardiography, Doppler
Humans
Mucocutaneous Lymph Node Syndrome*
Ventricular Function*